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Full-Text Articles in Biology
The Role Of Diet In Inflammatory Bowel Diseases, Aviva Smilow
The Role Of Diet In Inflammatory Bowel Diseases, Aviva Smilow
The Science Journal of the Lander College of Arts and Sciences
Inflammatory Bowel Disease encompasses two diseases, Crohn’s Disease and Ulcerative Colitis. During the last 70 years the evolving of diet in the industrialized countries has led to the utilization of foods that have been processed rather than those in their more natural original state. This increase in the processing of foods has been correlated with the more recent occurrence of metabolic diseases such as Inflammatory Bowel Disease. Patients suffering from this problem exhibit lesser amounts of anti-inflammatory bacteria such as Roseburia and Faecalibacterium and increased amounts of pro-inflammatory bacteria Escheria and Fusobacterium. Since diet directly alters the composition of the …
The Biophysical Study Of The Efficacy Of Various Phospholipid Membranes On Daptomycin, Chaya Shor, Tamar Itzkowitz
The Biophysical Study Of The Efficacy Of Various Phospholipid Membranes On Daptomycin, Chaya Shor, Tamar Itzkowitz
The Science Journal of the Lander College of Arts and Sciences
Daptomycin is an important lipopeptide antibiotic used in the treatment of systematic and life-threatening infections of the skin and underlying tissue caused by Gram-positive bacteria. Calcium and phosphatidylglycerol (PG) must be present on the target cell membrane for daptomycin’s mechanism of action to proceed. Calcium and PG also promote oligomerization, a formation that has been assumed to aid in the bactericidal process. The purpose of the experiments conducted was to understand the basic biophysical properties of membrane phospholipids as they exist in their pure and mixed monolayer forms. Furthermore, the experiments conducted attempted to discern how daptomycin penetrates the different …