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The Association Between Herpes Simplex Virus Type 1 Reactivation And Alzheimer’S Disease, Andrew Allee
The Association Between Herpes Simplex Virus Type 1 Reactivation And Alzheimer’S Disease, Andrew Allee
BIO 410 Spring 2019 Research Papers
This review will focus on the interaction of herpes simplex virus type 1 (HSV-1) and its causative role in pathogenesis of Alzheimer’s disease (AD) noting specifically, the epidemiological relevance of addressing this problem, as well as the molecular pathways associated. HSV-1 reactivation tends to be one of the primary causative events that is responsible for many of the pathologies associated with AD, such as: amyloid beta (Aβ) accumulation caused by malfunctioning cleavage of amyloid precursor protein (APP) as well as tau hyperphosphorylation. HSV-1 reactivation is a primary causative event in downstream dysfunction and is also shown to be directed by …
Tissue-Engineered Grafts: The Future Of Anterior Cruciate Ligament Reconstructive Surgery, Amber Braxton
Tissue-Engineered Grafts: The Future Of Anterior Cruciate Ligament Reconstructive Surgery, Amber Braxton
BIO 410 Spring 2019 Research Papers
Anterior cruciate ligament (ACL) ruptures are common injuries, specifically for young athletes, and in order to repair this injury, the patients must undergo ACL reconstructive surgery. This surgery commissions the use of autografts and allografts in order rebuild the torn ligament. Traditional autografts are the patellar tendon autograft, which is the most common, and the hamstring autograft. These grafts are made by transplanting tissue from the patellar tendon or the hamstring to the ruptured ACL. Allografts are another type of graft that involves transplanting tissue from a donor cadaver to the patient. Traditional autografts and allografts have been used for …