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Engaging Students In A Genetics Course-Based Undergraduate Research Experience Utilizing Caenorhabditis Elegans In Hybrid Learning To Explore Human Disease Gene Variants, Natalie Forte, Virginia Veasey, Bethany Christie, Amira Carter, Marli Hanks, Alan Holderfield, Taylor Houston, Anil Challa, Ashley Turner
Engaging Students In A Genetics Course-Based Undergraduate Research Experience Utilizing Caenorhabditis Elegans In Hybrid Learning To Explore Human Disease Gene Variants, Natalie Forte, Virginia Veasey, Bethany Christie, Amira Carter, Marli Hanks, Alan Holderfield, Taylor Houston, Anil Challa, Ashley Turner
Research, Publications & Creative Work
Genetic analysis in model systems using bioinformatic approaches provides a rich context for a concrete and conceptual understanding of gene structure and function. With the intent to engage students in research and explore disease biology utilizing the nematode Caenorhabditis elegans model, we developed a semester-long course-based undergraduate research experience (CURE) in a hybrid (online/in-person) learning environment—the gene-editing and evolutionary nematode exploration CURE (GENE-CURE). Using a combination of bioinformatic and molecular genetic tools, students performed structure-function analysis of disease-associated variants of uncertain significance (VUS) in human orthologs. With the aid of a series of workshop-style research sessions, students worked in teams …
Marine Parasites And Fish: How To Sample And Analyze. Subjects: Life Science / Biology, Environmental Science, Marine / Ocean Science Grades: 6-8, Zoemma Warshafsky
Marine Parasites And Fish: How To Sample And Analyze. Subjects: Life Science / Biology, Environmental Science, Marine / Ocean Science Grades: 6-8, Zoemma Warshafsky
Reports
This lesson plan provides a hands-on way for students to investigate the impacts of an invasive parasitic nematode which has been targeting the American eel. Students will first “infect” pipe cleaner eels with parasitic nematodes (beads), which will then be used to simulate real-life research efforts through collecting multiple random samples of “eels” and counting the amount of parasites. They will then use this data to calculate prevalence, mean intensity, and mean abundance.