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Full-Text Articles in Bioinformatics
Assessing Population Level Genetic Instability Via Moving Average, Samuel Mcdaniel, Rebecca Betensky, Tianxi Cai
Assessing Population Level Genetic Instability Via Moving Average, Samuel Mcdaniel, Rebecca Betensky, Tianxi Cai
Harvard University Biostatistics Working Paper Series
No abstract provided.
Assessment Of A Cgh-Based Genetic Instability, David A. Engler, Yiping Shen, J F. Gusella, Rebecca A. Betensky
Assessment Of A Cgh-Based Genetic Instability, David A. Engler, Yiping Shen, J F. Gusella, Rebecca A. Betensky
Harvard University Biostatistics Working Paper Series
No abstract provided.
Survival Analysis With Large Dimensional Covariates: An Application In Microarray Studies, David A. Engler, Yi Li
Survival Analysis With Large Dimensional Covariates: An Application In Microarray Studies, David A. Engler, Yi Li
Harvard University Biostatistics Working Paper Series
Use of microarray technology often leads to high-dimensional and low- sample size data settings. Over the past several years, a variety of novel approaches have been proposed for variable selection in this context. However, only a small number of these have been adapted for time-to-event data where censoring is present. Among standard variable selection methods shown both to have good predictive accuracy and to be computationally efficient is the elastic net penalization approach. In this paper, adaptation of the elastic net approach is presented for variable selection both under the Cox proportional hazards model and under an accelerated failure time …
Conservative Estimation Of Optimal Multiple Testing Procedures, James E. Signorovitch
Conservative Estimation Of Optimal Multiple Testing Procedures, James E. Signorovitch
Harvard University Biostatistics Working Paper Series
No abstract provided.