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Full-Text Articles in Bioinformatics
Proceedings Of The 2014 Midsouth Computational Biology And Bioinformatics Society (Mcbios) Conference, Jonathan D. Wren, Mikhail G. Dozmorov, Dennis Burian, Andy Perkins, Chaoyang Zhang, Peter Hoyt, Rakesh Kaundal
Proceedings Of The 2014 Midsouth Computational Biology And Bioinformatics Society (Mcbios) Conference, Jonathan D. Wren, Mikhail G. Dozmorov, Dennis Burian, Andy Perkins, Chaoyang Zhang, Peter Hoyt, Rakesh Kaundal
Faculty Publications
No abstract provided.
Smoq: A Tool For Predicting The Absolute Residue-Specific Quality Of A Single Protein Model With Support Vector Machine, Renzhi Cao, Zheng Wang, Yiheng Wang, Jianlin Cheng
Smoq: A Tool For Predicting The Absolute Residue-Specific Quality Of A Single Protein Model With Support Vector Machine, Renzhi Cao, Zheng Wang, Yiheng Wang, Jianlin Cheng
Faculty Publications
Background: It is important to predict the quality of a protein structural model before its native structure is known. The method that can predict the absolute local quality of individual residues in a single protein model is rare, yet particularly needed for using, ranking and refining protein models.
Results: We developed a machine learning tool (SMOQ) that can predict the distance deviation of each residue in a single protein model. SMOQ uses support vector machines (SVM) with protein sequence and structural features (i.e. basic feature set), including amino acid sequence, secondary structures, solvent accessibilities, and residue-residue contacts to …