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Articles 1 - 3 of 3
Full-Text Articles in Biochemistry, Biophysics, and Structural Biology
Snow Buntings Maintain Winter-Level Cold Endurance While Migrating To The High Arctic, Audrey Le Pogam, Ryan S. O’Connor, Oliver P. Love, Justine Drolet, Lyette Régimbald, Gabrielle Roy, Marie Pier Laplante, Dominique Berteaux, Andrew Tam, François Vézina
Snow Buntings Maintain Winter-Level Cold Endurance While Migrating To The High Arctic, Audrey Le Pogam, Ryan S. O’Connor, Oliver P. Love, Justine Drolet, Lyette Régimbald, Gabrielle Roy, Marie Pier Laplante, Dominique Berteaux, Andrew Tam, François Vézina
Great Lakes Institute for Environmental Research Publications
Arctic breeding songbirds migrate early in the spring and can face winter environments requiring cold endurance throughout their journey. One such species, the snow bunting (Plectrophenax nivalis), is known for its significant thermogenic capacity. Empirical studies suggest that buntings can indeed maintain winter cold acclimatization into the migratory and breeding phenotypes when kept captive on their wintering grounds. This capacity could be advantageous not only for migrating in a cold environment, but also for facing unpredictable Arctic weather on arrival and during preparation for breeding. However, migration also typically leads to declines in the sizes of several body components linked …
Investigating A Novel Function For Phosphoserine Aminotransferase 1 (Psat1) In Epidermal Growth Factor Receptor (Egfr)-Mediated Lung Tumorigenesis., Rumeysa Biyik-Sit
Investigating A Novel Function For Phosphoserine Aminotransferase 1 (Psat1) In Epidermal Growth Factor Receptor (Egfr)-Mediated Lung Tumorigenesis., Rumeysa Biyik-Sit
Electronic Theses and Dissertations
Phosphoserine aminotransferase 1 (PSAT1) catalyzes the second enzymatic step within the serine synthetic pathway (SSP) and its expression is elevated in numerous human cancers, including non-small cell lung cancer (NSCLC). Epidermal growth factor receptor (EGFR) mutant NSCLC is characterized by activating mutations within its tyrosine kinase domain and accounts for 17% of lung adenocarcinomas. Although elevated SSP activity has been observed in EGFR-mutant lung cancer cells, the involvement of PSAT1 in EGFR-mediated oncogenesis is still unclear. Here, we explore a putative non-canonical function for PSAT1 using biochemical approaches to elucidate unknown interacting proteins and genomic RNA-seq profiling to identify cellular …
Habitat Loss On The Breeding Grounds Is A Major Contributor To Population Declines In A Long-Distance Migratory Songbird, Michael T. Hallworth, Erin Bayne, Emily Mckinnon, Oliver Love, Junior A. Tremblay, Bruno Drolet, Jacques Ibarzabal, Steven Van Wilgenburg, Peter P. Marra
Habitat Loss On The Breeding Grounds Is A Major Contributor To Population Declines In A Long-Distance Migratory Songbird, Michael T. Hallworth, Erin Bayne, Emily Mckinnon, Oliver Love, Junior A. Tremblay, Bruno Drolet, Jacques Ibarzabal, Steven Van Wilgenburg, Peter P. Marra
Great Lakes Institute for Environmental Research Publications
Many migratory species are declining and for most, the proximate causes of their declines remain unknown. For many long-distance Neotropical migratory songbirds, it is assumed that habitat loss on breeding or non-breeding grounds is a primary driver of population declines. We integrated data collected from tracking technology, community science and remote sensing data to quantify migratory connectivity (MC), population trends and habitat loss. We quantified the correlation between forest change throughout the annual cycle and population declines of a long-distance migratory songbird, the Connecticut warbler (Oporornis agilis, observed decline: -8.99% yr -1). MC, the geographic link between populations during two …