Biochemistry, Biophysics, and Structural Biology Commons^™

Toxicological Analysis Of Stilbenes Against The Fall Armyworm, Spodoptera Frugiperda, Sarah E. Mccomic, Leslie C. Rault, Troy D. Anderson, Daniel R. Swale

Department of Entomology: Faculty Publications

The fall armyworm (FAW), Spodoptera frugiperda, is a global pest of multiple economically important row crops and the development of resistance to commercially available insecticidal classes has inhibited FAW control. Thus, there is a need to identify chemical scaffolds that can provide inspiration for the development of novel insecticides for FAW management. This study aimed to assess the sensitivity of central neurons and susceptibility of FAW to chloride channel modulators to establish a platform for repurposing existing insecticides or designing new chemicals capable of controlling FAW. Potency of select chloride channel modulators were initially studied against FAW central neuron …