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Biochemistry, Biophysics, and Structural Biology Commons™
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Articles 1 - 13 of 13
Full-Text Articles in Biochemistry, Biophysics, and Structural Biology
Bioinformatic And Experimental Approaches For Deeper Metaproteomic Characterization Of Complex Environmental Samples, Ramsunder Mahadevan Iyer
Bioinformatic And Experimental Approaches For Deeper Metaproteomic Characterization Of Complex Environmental Samples, Ramsunder Mahadevan Iyer
Doctoral Dissertations
The coupling of high performance multi-dimensional liquid chromatography and tandem mass spectrometry for characterization of microbial proteins from complex environmental samples has paved the way for a new era in scientific discovery. The field of metaproteomics, which is the study of protein suite of all the organisms in a biological system, has taken a tremendous leap with the introduction of high-throughput proteomics. However, with corresponding increase in sample complexity, novel challenges have been raised with respect to efficient peptide separation via chromatography and bioinformatic analysis of the resulting high throughput data. In this dissertation, various aspects of metaproteomic characterization, including …
Investigating The Regulation Of Indole-3-Acetic Acid Production By The Plant Associated Microbe Pantoea Sp. Yr343, Kasey Noel Estenson
Investigating The Regulation Of Indole-3-Acetic Acid Production By The Plant Associated Microbe Pantoea Sp. Yr343, Kasey Noel Estenson
Doctoral Dissertations
The auxin indole-3-acetic acid (IAA) plays a central role in plant growth and development and many plant-associated microbes produce IAA. Several IAA biosynthetic pathways have been identified in microbes which use the precursor tryptophan. Pantoea sp. YR343, which was isolated from the Populus deltoides rhizosphere, is a robust plant root colonizer that produces IAA. Using genomic and metabolomics analyses, we predicted that the indole-3-pyruvate (IPA) pathway is the major pathway in Pantoea sp. YR343 for IAA production. To better understand IAA biosynthesis and the effects of IAA exposure on cell physiology, we performed proteomics on Pantoea sp. YR343 grown in …
Design And Synthesis Of Analogs Of Myo-Inositol, Serine, And Cysteine To Enable Chemical Biology Studies, Tanei J. Ricks
Design And Synthesis Of Analogs Of Myo-Inositol, Serine, And Cysteine To Enable Chemical Biology Studies, Tanei J. Ricks
Doctoral Dissertations
Phosphorylated myo-inositol compounds including inositol phosphates (InsPs) as well as the phosphatidylinositol polyphosphate lipids (PIPns) are critical biomolecules that regulate many of the most important biological processes and pathways. They are aberrant in many disease states due to their regulatory function. The same is true of the phospholipid phosphatidylserine (PS) which can serve as a marker to begin apoptosis. However, the full scope of activities of these structures is not clear, particularly since techniques that enable global detection and analysis of the production of these compounds spatially and temporally are lacking. With all of these obstacles in …
Tea Induction Of Cyp6a8 Promoter In Drosophila Melanogaster, Fiona Retzer
Tea Induction Of Cyp6a8 Promoter In Drosophila Melanogaster, Fiona Retzer
Chancellor’s Honors Program Projects
No abstract provided.
Detection, Diversity, And Evolution Of Fungal Nitric Oxide Reductases (P450nor), Steven Adam Higgins
Detection, Diversity, And Evolution Of Fungal Nitric Oxide Reductases (P450nor), Steven Adam Higgins
Doctoral Dissertations
Nitrous oxide (N2O) is a gas responsible for significant ozone layer depletion and contributes to greenhouse effects in Earth’s atmosphere. N2O is primarily generated by denitrification, whereby nitrate (NO3-) or nitrite (NO2-) is converted to gaseous N2O or N2. Teragram quantities of N2O are emitted annually from agricultural soils treated with nitrogenous fertilizers due to the activity of soil microbiota. Although bacteria and fungi harbor genes permitting denitrification, fungi lack NosZ, an enzyme responsible for reducing N2O into inert N2 gas. Historically, scientists have linked fungi …
Characterizing Tmx And Chemotactic Receptor Arrays Through Bacterial Two-Hybrid And Beta-Galactosidase Assays, Adam Keith Hubler
Characterizing Tmx And Chemotactic Receptor Arrays Through Bacterial Two-Hybrid And Beta-Galactosidase Assays, Adam Keith Hubler
Faculty Publications and Other Works -- Biochemistry, Cellular and Molecular Biology
No abstract provided.
A Study On The Interactions Of Trehalose With Model Folate Compounds, Carolyn R Ware
A Study On The Interactions Of Trehalose With Model Folate Compounds, Carolyn R Ware
Chancellor’s Honors Program Projects
No abstract provided.
Myosin Xi-I Works In Tandem With A Microtubule-Associated Mechanism To Position The Nucleus In Arabidopsis Root Hairs, Ian Andrew Windham
Myosin Xi-I Works In Tandem With A Microtubule-Associated Mechanism To Position The Nucleus In Arabidopsis Root Hairs, Ian Andrew Windham
Chancellor’s Honors Program Projects
No abstract provided.
The Crowding Effects Of Rmlc On R67 And Chromosomal Dihydrofolate Reductase Enzymes, Michael A. Craig
The Crowding Effects Of Rmlc On R67 And Chromosomal Dihydrofolate Reductase Enzymes, Michael A. Craig
Chancellor’s Honors Program Projects
No abstract provided.
Effects Of Nicotine On The Cyp6a8 Gene Promoter Of Drosophila Melanogaster, Leslie M. Stroud
Effects Of Nicotine On The Cyp6a8 Gene Promoter Of Drosophila Melanogaster, Leslie M. Stroud
Chancellor’s Honors Program Projects
No abstract provided.
Evaluation Of Receptor Protein Too Many Mouths (Tmm) As A Glycosylphosphatidylinositol-Anchored Protein, Emily J. Miller
Evaluation Of Receptor Protein Too Many Mouths (Tmm) As A Glycosylphosphatidylinositol-Anchored Protein, Emily J. Miller
Chancellor’s Honors Program Projects
No abstract provided.
Comparative Chemical Characterization Of Lunasin-Enriched Preparations And Modifications Of The Inflammasomes In Vitro, Samuel James Price
Comparative Chemical Characterization Of Lunasin-Enriched Preparations And Modifications Of The Inflammasomes In Vitro, Samuel James Price
Masters Theses
Soybean (Glycine max) is one of the most cultivated crops in the world providing the population with large amounts of protein and oil. In addition to its nutritional composition, soybean also contains biologically active compounds with potential health-promoting properties. The presence of these bioactives may be responsible for the lower incidence of chronic diseases in populations that consume a significant portion of soybeans in their diet. One group of soybeanderived bioactives are bioactive peptides and proteins including lunasin, Bowman-Birk inhibitor (BBI) and Kunitz-type trypsin inhibitor (KTI). The overall objective of this research was to develop a method of …
Characterizing Tmx And Chemotactic Receptor Arrays Through Bacterial Two-Hybrid And Beta-Galactosidase Assays, Adam Keith Hubler
Characterizing Tmx And Chemotactic Receptor Arrays Through Bacterial Two-Hybrid And Beta-Galactosidase Assays, Adam Keith Hubler
Chancellor’s Honors Program Projects
No abstract provided.