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Full-Text Articles in Biochemistry, Biophysics, and Structural Biology

Diversity Of The Major Histocompatibility Complex In African Penguins (Spheniscus Demersus) In Situ, Athena Schalk Apr 2020

Diversity Of The Major Histocompatibility Complex In African Penguins (Spheniscus Demersus) In Situ, Athena Schalk

Undergraduate Honors Thesis Projects

The Major Histocompatibility Complex (MHC) is responsible for the immune response in all jawed vertebrates and protects individuals against a variety of pathogens and diseases. Maintaining genetic diversity within the MHC exons is critical to protecting endangered species. African penguins (Spheniscus demersus) are in danger of losing their MHC diversity in isolated populations due to reductions in population size associated with environmental changes and human activity. This study analyzes the diversity within the exons in the DNA encoding the MHC by amplifying the exons through polymerase chain reaction and identifying alleles through denaturing gradient gel electrophoresis. Wild populations of …


A Genetic Analysis Of Bald Eagles In The Pacific Northwest: Retained Genetic Diversity Following A Large-Scale Population Bottleneck, Andrew Joseph Nadeau Aug 2012

A Genetic Analysis Of Bald Eagles In The Pacific Northwest: Retained Genetic Diversity Following A Large-Scale Population Bottleneck, Andrew Joseph Nadeau

Boise State University Theses and Dissertations

Bald eagle (Haliaeetus leucocephalus) populations in the continental United States experienced a dramatic population decline during the twentieth century. Populations across the species’ range have largely recovered, thanks in part to the ban of DDT, rapidly enacted conservation measures, and reintroduction efforts. Using six microsatellite loci, I tested the genetic variation of bald eagles across six states in the Pacific Northwest. Genetic analysis revealed that, despite undergoing a population-wide decline, the bald eagles in the locations sampled outside of Idaho did not exhibit the characteristics typically associated with a genetic bottleneck (i.e., a reduced number of alleles and …