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Full-Text Articles in Biochemistry, Biophysics, and Structural Biology

Anatomy And Physiology Preparatory Course Textbook (2nd Edition), Carlos Liachovitzky Aug 2021

Anatomy And Physiology Preparatory Course Textbook (2nd Edition), Carlos Liachovitzky

Open Educational Resources

The goal of this preparatory textbook is to give students a chance to become familiar with some terms and some basic concepts they will find later on in the Anatomy and Physiology course, especially during the first few weeks of the course.

Organization and functioning of the human organism are generally presented starting from the simplest building blocks, and then moving into levels of increasing complexity. This textbook follows the same presentation. It begins introducing the concept of homeostasis, then covers the chemical level, and later on a basic introduction to cellular level, organ level, and organ system level. This …


Simulated Breathing: Application Of Molecular Dynamics Simulations To Pulmonary Lung Surfactant, Maksymilian Dziura, Basel Mansour, Mitchell Dipasquale, P. Charukeshi Chandrasekera, James W. Gauld, Drew Marquardt Jul 2021

Simulated Breathing: Application Of Molecular Dynamics Simulations To Pulmonary Lung Surfactant, Maksymilian Dziura, Basel Mansour, Mitchell Dipasquale, P. Charukeshi Chandrasekera, James W. Gauld, Drew Marquardt

Chemistry and Biochemistry Publications

In this review, we delve into the topic of the pulmonary surfactant (PS) system, which is present in the respiratory system. The total composition of the PS has been presented and explored, from the types of cells involved in its synthesis and secretion, down to the specific building blocks used, such as the various lipid and protein components. The lipid and protein composition varies across species and between individuals, but ultimately produces a PS monolayer with the same role. As such, the composition has been investigated for the ways in which it imposes function and confers peculiar biophysical characteristics to …


Protein Composition: Translating Amino Acid Sequences Into Music, Melody Campbell Apr 2021

Protein Composition: Translating Amino Acid Sequences Into Music, Melody Campbell

WWU Honors College Senior Projects

Proteins are composed of individual building blocks (amino acids) assembled in a chain, resembling beads on a string. This string – or sequence of amino acids – folds into a unique three-dimensional shape to form a fully functional protein. In nature, there are 20 different naturally occurring amino acids. I assigned specific musical chords to each different amino acid and arranged the chords sequentially in an order that mirrored the sequence of amino acids. The resulting composition contains a pattern of chords representative of the protein’s amino acid sequence. For example, if Glycine (one of the 20 natural amino acids) …