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Full-Text Articles in Biochemistry, Biophysics, and Structural Biology
Studying Acetylation Of Aconitase Isozymes By Genetic Code Expansion, Jessica Araujo
Studying Acetylation Of Aconitase Isozymes By Genetic Code Expansion, Jessica Araujo
Graduate Theses and Dissertations
The tricarboxylic acid (TCA) cycle is a very important, centrally located, energy-producing pathway that connects numerous other metabolic and regulatory pathways. Enzymes of this cycle have been more recently implicated in various cancers and neurometabolic disorders, however, the exact mechanism by which this happens becomes quite complex when considering the potential modification of these enzymes and the presence of multiple forms of the enzymes and therefore there is much to be studied in this area.
Aconitase has become a recent enzyme of interest as its substrate, citrate, has been found to play a major role in many vital processes within …