Biochemistry, Biophysics, and Structural Biology Commons^™

Expression, Characterization, And Investigation Of The Thermal Stability Of Fibroblast Growth Factor (Fgf) 19, Ridhikaanth Kalaiselvan

Chemistry & Biochemistry Undergraduate Honors Theses

Fibroblast growth factors are a family of cell signaling proteins that have the ability to bind to heparin and are involved in a wide range of physiological functions, such as angiogenesis, cell differentiation, cell proliferation, cell morphogenesis, and wound healing. Fibroblast growth factor (FGF) 19 is a signaling protein belonging to this large family of fibroblast growth factors (FGFs). FGF19 has a pronounced effect on various biological processes, including cell proliferation, cholesterol and lipid catabolism, and glucose homeostasis. As such, FGF19 is known to play an integral role in regulating many metabolic diseases, which piques the interest of the science …