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Full-Text Articles in Biochemistry, Biophysics, and Structural Biology
Understanding The Role Of Charge On Particle Transport Within Semidilute And Concentrated Biopolymer Solutions And Tau Protein Condensates, Kanthi Nuti
Theses and Dissertations--Chemistry
Biological polymer networks such as mucus, extracellular matrix, nuclear pore complex, and bacterial biofilms, play a critical role in governing the transport of nutrients, biomolecules and particles within cells and tissues. The interactions between particle and polymer chains are responsible for effective selective filtering of particles within these macromolecular networks. This selective filtering is not dictated by steric alone but must use additional interactions such electrostatics, hydrophobic and hydrodynamic effects to control particle transport within biogels. Depending on chemical composition and desired function, biogels use selective filtering to allow some particles to permeate while preventing others from penetrating the biogel. …