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Full-Text Articles in Biochemistry, Biophysics, and Structural Biology
Assessing Tissue Characterization Of Abdominal Organs Using Fuzzy C-Means Cluster Analysis Of Color- Fusion Mr Images, Terrance D. Weeden, H. Keith Brown
Assessing Tissue Characterization Of Abdominal Organs Using Fuzzy C-Means Cluster Analysis Of Color- Fusion Mr Images, Terrance D. Weeden, H. Keith Brown
Terrance Weeden
Color fusion MRI is being investigated for its value in automatic segmentation of tissues. An existing color fusion MRI data set of the liver, pancreas, and kidney of a normal male volunteer was analyzed both visually and statistically. Automatic tissue segmentation can allow better differentiation of abdominal pathologies, as well as pathologies associated with other organs. My research hypothesis is that fuzzy c-means clustering can be used to quantify the confidence levels of the correct classification of renal, pancreatic, and hepatic tissues visualized by the color fusion MRI method. Results from data show that fuzzy c-means clustering can be used …
Rab5 Function In Breast Cancer Cells, Nicole Porther, M Alejandro Barbieri
Rab5 Function In Breast Cancer Cells, Nicole Porther, M Alejandro Barbieri
Nicole Porther
Metastasis is characterized pathologically by cell invasion, proliferation, migration and angiogenesis. Growth factors, which include epithelial growth factor (EGF), insulin growth factors I and II (IGFI and IGFII); have been associated with most if not all of the features of metastasis. Our study has highlighted the possible role growth factors may have in mediating cancer metastasis via Rab GTPses. We determined that the invasive and migratory properties of breast cancer cells were abrogated in cell lines that only expressed the inactive (GDP-bound) form of Rab 5 irrespective of growth factor stimulation. Breast cancer cell lines expressing the wild type and …