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Full-Text Articles in Biochemistry, Biophysics, and Structural Biology
Dissection Of The Genetic Architecture Of Grain Quality In Rice, Shuai Liu
Dissection Of The Genetic Architecture Of Grain Quality In Rice, Shuai Liu
Theses and Dissertations
Rice is an important human staple food for over half of the world’s population. Amylose content (AC), gelatinization temperature (GT), grain protein content (GPC), percentage grain chalkiness (PGC), and mineral content are important parameters for evaluating rice quality, which attracts customers and breeders. Only limited genes or QTLs (OsAAP6, OsGluA2, OsASN1, Chalk5, OsHMA3, etc.) are reported regulating rice GPC, PGC, and mineral content due to the lack of genetic knowledge and molecular markers. To dissect the genetic architecture of rice grain quality regulation, genome wide association studies (GWAS) were performed using two populations …
A Review Of Calcineurin Biophysics With Implications For Cardiac Physiology, Ryan B. Williams
A Review Of Calcineurin Biophysics With Implications For Cardiac Physiology, Ryan B. Williams
Theses and Dissertations
Calmodulin is a prevalent calcium sensing protein found in all cells. Three genes exist for calmodulin and all three of these genes encode for the exact same protein sequence. Recently mutations in the amino acid sequence of calmodulin have been identified in living human patients. Thus far, patients harboring these mutations in the calmodulin sequence have only displayed an altered cardiac related phenotype. Calcineurin is involved in many key physiological processes and its activity is regulated by calcium and calmodulin. In order to assess whether or not calcineurin contributes to calmodulinopathy (a pathological state arising from dysfunctional calmodulin), a comprehensive …