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Full-Text Articles in Biochemistry, Biophysics, and Structural Biology

Analysis Of Vehicle Use Patterns During Military Field Exercises To Identify Potential Roads, Chunxia Wu Dec 2005

Analysis Of Vehicle Use Patterns During Military Field Exercises To Identify Potential Roads, Chunxia Wu

Doctoral Dissertations

Military training is an intensive land use and can cause negative environmental effects. Many studies conducted under Integrated Training Area Management (ITAM) for quantifying the impact resulted from the military training exercise found that off-road vehicular activities during training exercises cause the major impact to the training land. Vehicle land use patterns at a certain location affect the impact severity: concentrated and repeated traffic create more serious damage to the land compared to the dispersed offroad vehicle movements. Those areas heavily disturbed by off-road traffic may require a longer period of time or special treatments for the land to return …


Identification And Expansion Of Pancreatic Stem/Progenitor Cells., You-Qing Zhang, Marcie Kritzik, Nora Sarvetnick Apr 2005

Identification And Expansion Of Pancreatic Stem/Progenitor Cells., You-Qing Zhang, Marcie Kritzik, Nora Sarvetnick

Journal Articles: Regenerative Medicine

Pancreatic islet transplantation represents an attractive approach for the treatment of diabetes. However, the limited availability of donor islets has largely hampered this approach. In this respect, the use of alternative sources of islets such as the ex vivo expansion and differentiation of functional endocrine cells for treating diabetes has become the major focus of diabetes research. Adult pancreatic stem cells /progenitor cells have yet to be recognized because limited markers exist for their identification. While the pancreas has the capacity to regenerate under certain circumstances, questions where adult pancreatic stem/progenitor cells are localized, how they are regulated, and even …


Selective Field Effects On Intracellular Vacuoles And Vesicle Membranes With Nanosecond Electric Pulses, Ephrem Tekle, Hammou Oubrahim, Sergey M. Dzekunov, Juergen F. Kolb, Karl H. Schoenbach Jan 2005

Selective Field Effects On Intracellular Vacuoles And Vesicle Membranes With Nanosecond Electric Pulses, Ephrem Tekle, Hammou Oubrahim, Sergey M. Dzekunov, Juergen F. Kolb, Karl H. Schoenbach

Bioelectrics Publications

Electric pulses across intact vesicles and cells can lead to transient increase in permeability of their membranes. We studied the integrity of these membranes in response to external electric pulses of high amplitude and submicrosecond duration with a primary aim of achieving selective permeabilization. These effects were examined in two separate model systems comprising of 1), a mixed population of 1,2-di-oleoyl-sn-glycero-3-phosphocholine phospholipid vesicles and in 2), single COS-7 cells, in which large endosomal membrane vacuoles were induced by stimulated endocytosis. It has been shown that large and rapidly varying external electric fields, with pulses shorter than the charging time of …