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Biochemistry, Biophysics, and Structural Biology Commons™
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- Air-water interface (1)
- Anisole (1)
- Benzene (1)
- Biomass burning (1)
- Brown cloud (1)
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- Carboxylic Acids (1)
- Catechols (1)
- Cell and Molecular biology (1)
- Combustion (1)
- Electron transfer (1)
- Fluorescence (1)
- Fragmentation (1)
- Functionalization (1)
- Lab-on-a-chip (1)
- Luminescence spectroscopy (1)
- Microfluidic devices (1)
- Nanoaperture-integrated microfluidic devices (1)
- Nanostructures (1)
- Optical materials (1)
- Oxidation-Reduction (1)
- Ozonolysis (1)
- Polyphenols (1)
- Polysiloxanes (1)
- Proteins (1)
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- Real-time sensing (1)
- Secondary organic aerosol (1)
- Single-ligand delivery (1)
- Toluene (1)
- Water (1)
Articles 1 - 2 of 2
Full-Text Articles in Biochemistry, Biophysics, and Structural Biology
Real-Time Sensing Of Single-Ligand Delivery With Nanoaperture-Integrated Microfluidic Devices, W. Elliott Martin, Ning Ge, Bernadeta R. Srijanto, Emily Furnish, C. Patrick Collier, Christine A. Trinkle, Christopher I. Richards
Real-Time Sensing Of Single-Ligand Delivery With Nanoaperture-Integrated Microfluidic Devices, W. Elliott Martin, Ning Ge, Bernadeta R. Srijanto, Emily Furnish, C. Patrick Collier, Christine A. Trinkle, Christopher I. Richards
Chemistry Faculty Publications
The measurement of biological events on the surface of live cells at the single-molecule level is complicated by several factors including high protein densities that are incompatible with single-molecule imaging, cellular autofluorescence, and protein mobility on the cell surface. Here, we fabricated a device composed of an array of nanoscale apertures coupled with a microfluidic delivery system to quantify single-ligand interactions with proteins on the cell surface. We cultured live cells directly on the device and isolated individual epidermal growth factor receptors (EGFRs) in the apertures while delivering fluorescently labeled epidermal growth factor. We observed single ligands binding to EGFRs, …
Oxidation Of Substituted Catechols At The Air-Water Interface: Production Of Carboxylic Acids, Quinones, And Polyphenols, Elizabeth A. Pillar, Marcelo I. Guzman
Oxidation Of Substituted Catechols At The Air-Water Interface: Production Of Carboxylic Acids, Quinones, And Polyphenols, Elizabeth A. Pillar, Marcelo I. Guzman
Chemistry Faculty Publications
Anthropogenic activities contribute benzene, toluene, and anisole to the environment, which in the atmosphere are converted into the respective phenols, cresols, and methoxyphenols by fast gas-phase reaction with hydroxyl radicals (HO(•)). Further processing of the latter species by HO(•) decreases their vapor pressure as a second hydroxyl group is incorporated to accelerate their oxidative aging at interfaces and in aqueous particles. This work shows how catechol, pyrogallol, 3-methylcatechol, 4-methylcatechol, and 3-methoxycatechol (all proxies for oxygenated aromatics derived from benzene, toluene, and anisole) react at the air-water interface with increasing O3(g) during τc ≈ 1 μs contact time and contrasts their …