Open Access. Powered by Scholars. Published by Universities.®
Biochemistry, Biophysics, and Structural Biology Commons™
Open Access. Powered by Scholars. Published by Universities.®
- Keyword
-
- Amine (1)
- Antisense (1)
- Apoptosis (1)
- Azobenzene (1)
- Biodiesel production (1)
-
- Biofuel oxidation (1)
- Biomimetic Synthesis (1)
- Brassica Carinata (1)
- Cancer (1)
- Catalysts (1)
- Cis/trans isomerization (1)
- Cross-coupling (1)
- Cytotoxic (1)
- Fatty-acid methyl-esters (1)
- Indole (1)
- Nanoparticles (1)
- PC3 (1)
- PNA duplexes (1)
- Palladium (1)
- Peanut (1)
- Peptide nucleic acids (1)
- Peptides (1)
- Peroxide Value (1)
- Photo switching (1)
- Suzuki-Miyaura (1)
Articles 1 - 4 of 4
Full-Text Articles in Biochemistry, Biophysics, and Structural Biology
Analysis Of The Light Responsive Azobenzene Peptide Nucleic Acid Duplexes, Kat Nguyen
Analysis Of The Light Responsive Azobenzene Peptide Nucleic Acid Duplexes, Kat Nguyen
Honors College Theses
Peptide nucleic acids (PNAs) are oligonucleotide analogues in which the sugar-phosphate backbone has been replaced by a pseudopeptide skeleton. Since PNAs use the natural nucleobases (Adenine, Thymine, Cytosine, Uracil, and Guanine) found in either DNA and/or RNA, they are able to hybridize according to Watson-Crick base-pairing to form duplexes. PNA is a promising therapeutic agent because they can function as antigene or antisense chemical agents. To further enhance their utility, we aim to incorporate a photoswitchable moiety using azobenzene. Here, we report the results of the synthesis and purification of a photoswitchable 11 mer PNA along with initial characterization efforts.
Biomimetic Synthesis Of Palladium Nanoparticles For Catalytic Application, Emily A. Groover
Biomimetic Synthesis Of Palladium Nanoparticles For Catalytic Application, Emily A. Groover
Electronic Theses and Dissertations
The synthesis of palladium nanoparticles (Pd NPs) using materials-directed peptides is a novel, nontoxic approach which exerts a high level of control over the particle size and shape. This biomimetic technique is environmentally benign, featuring nonhazardous ligands and ambient conditions. Nanoparticles are extremely reactive catalysts, boasting a large surface-to-volume ratio when compared to their bulk counterparts. The rational design of these nanoparticles using peptides has been very successful in aqueous environments, but no research has been done to apply it in organic systems. As such, the biomimetic synthesis of Pd NPs in an organic system is here investigated, with ethanol …
Synthesized Tripodal Amine As Potential Anti-Cancer Therapeutic, Abigail G. Mcnamee
Synthesized Tripodal Amine As Potential Anti-Cancer Therapeutic, Abigail G. Mcnamee
Honors College Theses
Cancer remains a prevalent disease today. This disease may manifest itself in many different ways and affect a variety of tissues with everything from the brain to the blood. With this wide diversity of cancer types, treatment can be complicated since there is not a “one size fits all” treatment for the disease. Surgery, radiation, and chemotherapy are all options that must be weighed with their benefits and side effects. Ultimately though, there are not enough effective treatment options available for every type of cancer. This leaves many with the grim prognosis of never being cured. With this clear need …
Carinata Fame Production Process And Biofuel Oxidation, Benoit Kindo
Carinata Fame Production Process And Biofuel Oxidation, Benoit Kindo
Honors College Theses
In this experiment, the contribution of a standard production method for biofuels on their oxidative stability was investigated. Peroxide values were measured at different steps of the production process of Brassica carinata and peanut-based biofuels. The washing and drying steps in this production method showed significant increases in peroxide values for both biofuels and was identified as a major contributor of biofuel oxidation. Further analyses of the physical and thermal properties showed a more pronounced affect in the biofuel from Bassica carinata, and indicated an unusual composition much higher in saturated fatty acids much longer than those found in peanut. …