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Full-Text Articles in Biochemistry, Biophysics, and Structural Biology
Can Biology Define A Human Life?, Katelyn De Leon
Can Biology Define A Human Life?, Katelyn De Leon
Regis University Student Publications (comprehensive collection)
I grew up contemplating the concept of life. From my Catholic grandmother to my pediatrician mother, I always received mixed perspectives on the hot topics of abortions, vaccines, and embryo use. I found that the controversy lies in an ambiguous, mixed understanding of what constitutes a human life. From biochemical approaches to extraterrestrial life forms and spirituality there is no clear, coherent all-encompassing definition of life. However, that does not mean we can merely agree to disagree. The concept of a human life has drastic implications on our everyday lives. An insufficient definition has, and will continue to, diminish quality …
Xenopus Adam13 And Adam19 Are Important For Proper Convergence And Extension Of The Notochord, Russell David Neuner
Xenopus Adam13 And Adam19 Are Important For Proper Convergence And Extension Of The Notochord, Russell David Neuner
Open Access Dissertations
Gastrulation is a fundamental process that reorganizes the primary germ layers to shape the internal and external features of an early embryo. Morphogenetic movements underlying this process can be classified into a variety of different types of cellular movements. I will focus on investigating in this thesis two types of cell movements in the dorsal mesoderm; mediolateral cell intercalation and convergence and extension. During gastrulation, mesoderm cells send protrusions to gain traction on neighboring cells and the surrounding extracellular matrix; a process called mediolateral cell intercalation. Mesoderm cells use this type of cell movement to converge and extend the dorsal …
Leukemia Inhibitory Factor (Lif): Murine Preimplantation Embryo Development, Implantation Rates, And Skeletal Development, Michael Hayes Mitchell
Leukemia Inhibitory Factor (Lif): Murine Preimplantation Embryo Development, Implantation Rates, And Skeletal Development, Michael Hayes Mitchell
Theses and Dissertations in Biomedical Sciences
Leukemia inhibitory factor (LIF) is a pleiotropic cytokine which demonstrates perplexing physiological effects. It has been demonstrated that LIF is essential for implantation in mice. Little is known relating to the manner by which LIF effects pre-implantation and post-implantation development. The objectives of this project were to determine the effects LIF on pre-implantation development, to determine the effects that it may have on implantation rates, successful pregnancy rates, and resorption rates, and to determine the effects that LIF has on the skeletal development of mice. For the embryo transfer experiments, embryos were exposed to test compounds in the transfer medium …