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Biochemistry, Biophysics, and Structural Biology Commons™
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Cell and Developmental Biology
Cathepsin L; Drosophila; Air Sac Primordium; Wing imaginal discs; Development
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Full-Text Articles in Biochemistry, Biophysics, and Structural Biology
Functional Characterization Of A Cathepsin L In Drosophila Melanogaster, Qian Dong
Functional Characterization Of A Cathepsin L In Drosophila Melanogaster, Qian Dong
Masters Theses & Specialist Projects
The Drosophila dorsal Air Sac Primordium (ASP) is a tracheal tube that invasively grows toward and into the wing imaginal disc. The unfolding of Drosophila wing is a process following eclosion with a cuticular bilayer replacing epithelial cells originally packing the wing. We reasoned that protease functions might be needed for the invasion of ASP into the wing imaginal disc as well as the rearrangement of epithelia cells during wing unfolding. Our study is particularly focused on understanding the role of a Cathepsin L like cysteine protease (CP1) in the development of dorsal ASP and wing development of Drosophila melanogaster. …