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Articles 1 - 5 of 5
Full-Text Articles in Biochemistry, Biophysics, and Structural Biology
Combined High-Speed Single Particle Tracking Of Membrane Proteins And Super-Resolution Of Membrane-Associated Structures, Hanieh Mazloom Farsibaf, Keith A. Lidke
Combined High-Speed Single Particle Tracking Of Membrane Proteins And Super-Resolution Of Membrane-Associated Structures, Hanieh Mazloom Farsibaf, Keith A. Lidke
Shared Knowledge Conference
Many experiments have shown that the diffusive motion of lipids and membrane proteins are slower on the cell surface than those in artificial lipid bilayers or blebs. One hypothesis that may partially explain this mystery is the effect of the cytoskeleton structures on the protein dynamics. A model proposed by Kusumi [1] is the Fence-Picket Model which describes the cell membrane as a set of compartment regions, each ~ 10 to 200 nm in size, created by direct or indirect interaction of lipids and proteins with actin filaments just below the membrane. To test this hypothesis, we have assembled a …
Study Of The Visual Adaptation Mechanism In Marine Species With The Change Of Habitation Depth., Demid Osipov, Daniil Moshnikov
Study Of The Visual Adaptation Mechanism In Marine Species With The Change Of Habitation Depth., Demid Osipov, Daniil Moshnikov
The International Student Science Fair 2018
The goal of our work was to determine the principal mechanisms that provide the difference in visual perception of two marine species that live on different depths: T. Pacificus and O. Vulgaris. In nature, visual perception of species that live deeper is shifted towards the blue region. This is related to the fact that red, orange and yellow light is absorbed more strongly by water than the blue light. On the other hand, the visual perception spectrum of an animal is determined by the absorption spectrum of the "light sensor" located in rods and cones of its eye retina. These …
Inference And Control In Regulatory Genomics, Siddharth Sharma
Inference And Control In Regulatory Genomics, Siddharth Sharma
Biology and Medicine Through Mathematics Conference
No abstract provided.
Computational Study Of Ligand-Dependent Oligomerization Of Ribonucleotide Reductase, Bill Pham
Computational Study Of Ligand-Dependent Oligomerization Of Ribonucleotide Reductase, Bill Pham
EURēCA: Exhibition of Undergraduate Research and Creative Achievement
Certain protein oligomerization can be strongly influenced by its ligand-binding status. We constructed a computational method to investigate how ligand-binding and oligomerization can be coupled. We tackle this issue using an approximate approach of studying the properties of individual monomers and how they associate. By connecting the dynamics at monomeric level and the information of oligomer interface, we quantify the synchronization of two types of contact dynamics: (1) between the ligand and its binding pocket, and (2) the contact dynamics at interface. In this work, we applied our methodology on protein ribonucleotide reductase (RNR), which is an essential enzyme for …
Maternal Protein Restriction (Mpr): A Risk Factor For Acute Respiratory Distress Syndrome (Ards), Reza Khazaee
Maternal Protein Restriction (Mpr): A Risk Factor For Acute Respiratory Distress Syndrome (Ards), Reza Khazaee
Western Research Forum
Background: Acute respiratory distress syndrome (ARDS) is defined as severe lung dysfunction. The lung impairments in ARDS result from alterations to pulmonary surfactant; a lipid-protein mixture coating the inside of the lung and maintains the lungs’ ability to expand easily. Due to a lack of effective pharmacological therapies mortality associated with ARDS is over 30%. Our research focuses on risk factors that indicate a susceptibility to the disease, which could provide new and early therapeutic options. One such potential risk factor is Maternal Protein Restriction (MPR). MPR is defined by low birth weight and contributes to a variety of adult-onset …