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Animal Sciences Commons

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All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

2010

Sheep

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Full-Text Articles in Animal Sciences

Investigation Of The Toxicity And Toxicokinetics Of Selenium From The Accumulator Plant Symphyotrichum Spathulatum (Western Mountain Aster) In Sheep, Amanda Wilhelm May 2010

Investigation Of The Toxicity And Toxicokinetics Of Selenium From The Accumulator Plant Symphyotrichum Spathulatum (Western Mountain Aster) In Sheep, Amanda Wilhelm

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

This study was designed to observe the effects of selenium from plant material in sheep after a single, oral dose. Purified sodium selenite and selenomethionine were given as positive controls. The plant Symphyotrichum spathulatum (Western Mountain Aster) was collected, analyzed for selenium content, and administered orally to sheep at varying doses according to body weight. Clinical signs were observed for 7 days during which time whole blood, serum, and expired air were collected. Following euthanasia, tissues were collected for histopathological analysis and mineral analysis.

Clinical signs were less apparent than expected and included depression and mild dyspnea in sheep receiving …