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Full-Text Articles in Agriculture

Toxicosis From Range Lupine Ingestion In A Research Herd Of Rafter 7 Merino Sheep, Benjamin J. Weigler, Walter F. Mandeville Iii, Scott Huber, Gary Mccuin, Fabrizio Caragena, Daniel D. Cook, Stephen T. Lee, Chris A. Pritsos Jun 2024

Toxicosis From Range Lupine Ingestion In A Research Herd Of Rafter 7 Merino Sheep, Benjamin J. Weigler, Walter F. Mandeville Iii, Scott Huber, Gary Mccuin, Fabrizio Caragena, Daniel D. Cook, Stephen T. Lee, Chris A. Pritsos

Poisonous Plant Research (PPR)

An outbreak of lupine alkaloid neurotoxicosis and death occurred in sheep grazed on rangeland areas of the Nevada Great Basin during the summer of 2023. Overall, 97 sheep died despite veterinary supportive care. Lupinus argenteus var. utahensis was implicated as the causative plant with high levels of lupanine (11.5 µg/mg) and spartiene (13.7 µg/mg) in collected and archived samples. Previous reports of sheep deaths due to lupine ingestion have not been recorded in this region. An increased abundance of the number plants producing seed pods having a high alkaloid content may have been associated with abnormally elevated levels of precipitation …


Aversion Properties Of Retrorsine, Retrorsine Nitrogen Oxide And Frosted Senecio Latifolius, Leendert D. Snyman Dec 2023

Aversion Properties Of Retrorsine, Retrorsine Nitrogen Oxide And Frosted Senecio Latifolius, Leendert D. Snyman

Poisonous Plant Research (PPR)

Two pilot trials, investigating the aversive properties of retrorsine and retrorsine nitrogen oxide and that of frosted Senecio latifolius, were executed. Retrorsine and retrorsine-NO (the toxic principles of Senecio retrorsus), unlke sceleratine-NO (the toxic principle of another hepatotoxic pyrrolizidine alkaloid containing plant, namely S. latifolius), were not capable of establishing aversion when given to a sheep. Frosted S. latifolius given to a sheep also did not induce aversion. However, a sheep averted to S. latifolius (non-frosted) refused eating frosted S. latifolius.


Sceleratin Nitrogen Oxide As Aversive Agent In Conditioning Livestock To Avoid Senecio Latifolius, Leendert D. Snyman Dec 2023

Sceleratin Nitrogen Oxide As Aversive Agent In Conditioning Livestock To Avoid Senecio Latifolius, Leendert D. Snyman

Poisonous Plant Research (PPR)

Sceleratine nitrogen oxide, when administered together with a dichloromethane extract of Senecio latifolius, successfully conditioned cattle and sheep to avoid milled freeze dried S. latifolius mixed with maize meal. This treatment was effectively applied in conditioning steers to refuse eating S. latifolius grown in pots.


Isolation Of The Toxic Principle Of Senecio Latifolius By Means Of The Sensory Receptors Of Sheep, Leendert D. Snyman Dec 2023

Isolation Of The Toxic Principle Of Senecio Latifolius By Means Of The Sensory Receptors Of Sheep, Leendert D. Snyman

Poisonous Plant Research (PPR)

The aversive substance of Senecio latifolius was isolated by means of the sensory receptors of sheep averted to S. latifolius. Chemical fractions refused due to the presence of the aversive substance sensed by the sheep were fractionated until a purified substance had been isolated. Nuclear magnetic resonance (NMR) analysis of the purified substance showed it to be sceleratine nitrogen oxide, the toxic principle of S. latifolius.