Life Sciences Commons^™

Using Mixed Effects Modeling To Quantify Difference Between Patient Groups With Diabetic Foot Ulcers, Rachel French

Mahurin Honors College Capstone Experience/Thesis Projects

When diabetes progresses, many patients suffer from chronic foot ulcers. In a study described in Matrix Metalloproteinases and Diabetic Foot Ulcers (Muller et al., 2008), sixteen patients with diabetic foot ulcers were examined throughout a twelve week healing period. During this period, levels of matrix metalloproteinases (MMP-1), their inhibitors (TIMP-1), and the extracellular matrix in a wound area were measured at distinct time intervals for each patient. The ratios of these healing components are vital in determining whether a wound will heal or become chronic and never properly heal. Connecting Local and Global Sensitivities in a Mathematical Model for Wound …

Use And Misuse Of The Likert Item Responses And Other Ordinal Measures, Phillip A. Bishop, Robert L. Herron

International Journal of Exercise Science

International Journal of Exercise Science 8(3): 297-302, 2015. Likert, Likert-type, and ordinal-scale responses are very popular psychometric item scoring schemes for attempting to quantify people’s opinions, interests, or perceived efficacy of an intervention and are used extensively in Physical Education and Exercise Science research. However, these numbered measures are generally considered ordinal and violate some statistical assumptions needed to evaluate them as normally distributed, parametric data. This is an issue because parametric statistics are generally perceived as being more statistically powerful than non-parametric statistics. To avoid possible misinterpretation, care must be taken in analyzing these types of data. The use …

An Integrated Neuroimaging Approach For The Prediction And Analysis Of Alzheimer’S Disease And Its Prodromal Stages, Qi Zhou

FIU Electronic Theses and Dissertations

This dissertation proposes to combine magnetic resonance imaging (MRI), positron emission tomography (PET) and a neuropsychological test, Mini-Mental State Examination (MMSE), as input to a multidimensional space for the classification of Alzheimer’s disease (AD) and it’s prodromal stages including amnestic MCI (aMCI) and non-amnestic MCI (naMCI). An assessment is provided on the effect of different MRI normalization techniques on the prediction of AD. Statistically significant variables selected for each combination model were used to construct the classification space using support vector machines. To combine MRI and PET, orthogonal partial least squares to latent structures is used as a multivariate analysis …

Zebra Image Access System, Srilekha Mudumbai, Kshitij Shah, Amit P. Sheth, Krishnan Parasuraman, Clemens Bertram

Kno.e.sis Publications

The ZEBRA system, which is part of the VisualHarness platform for managing heterogeneous data, supports three types of access to distributed image repositories: keyword based, attribute based, and image content based. A user can assign different weights (relative importance) to each of the three types, and within the last type of access, to each of the image properties. The image based access component (IBAC) supports access based on computable image properties such as those based on spatial domain, frequency domain or statistical and structural analysis. However, it uses a novel black box approach of utilizing a Visual Information Retrieval (VIR) …

Quantitative Evaluation Of Scanning Electron Microscopy-Examined Ciliary Morphological Changes In Control And Noise Exposed Guinea Pig Cochleas, S. Rydmarker, P. Nilsson, D. E. Dunn, C. Lindqvist

Scanning Microscopy

Many investigations of noise-induced hearing loss have demonstrated a poor correlation between hearing threshold and hair cell loss. One reason for this is that more subtle changes in the hair cell, such as detailed morphological changes of stereocilia, have not been evaluated. However, examining such changes increases the problem of distinguishing experimental pathological changes from artefacts. Preparation of the specimen for scanning electron microscopy (SEM) may result in too many artefacts for an adequate quantification of defects due to noise exposure.

One problem with some earlier studies seems to be lack of controls and/or statistical analysis for the purpose of …

Suitability Analysis And Wildland Classification: An Approach, D.R. Betters, J.L. Rubingh

Aspen Bibliography

The determination of wildland suitability for various uses and their proper classification for use is becoming increasingly important to planning.

Estimating Aspen Crown Fuels In Northeastern Minnesota, R.M. Loomis, P.J. Roussopoulos

Aspen Bibliography

No abstract provided.