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Articles 1 - 19 of 19

Full-Text Articles in Life Sciences

Physiological Effects Of A Traditional Active Warm-Up Versus A Passive Warm-Up During Submaximal Endurance Exercise, Vernice Ollano May 2023

Physiological Effects Of A Traditional Active Warm-Up Versus A Passive Warm-Up During Submaximal Endurance Exercise, Vernice Ollano

UNLV Theses, Dissertations, Professional Papers, and Capstones

The purpose of this study is to investigate physiological responses during a traditional active warm-up and a passive warm-up consisting of wearing heated trousers during a submaximal endurance cycling workout. Participants included 10 cyclists/triathletes (3 females, 7 males; age: 48 ± 13 years old; mass: 157.9 ± 33.8 kg; height: 169.3 ± 8.65 cm; percent body fat: 25.3 ± 8.53 %) of at least 18 years of age who could continuously cycle for at least 120 minutes and had knowledge of their individual FTP. Experimental 1-day testing included a randomized crossover design where participants proceeded with two different protocols: an …


Eftilagimod Alpha, A Soluble Lymphocyte Activation Gene-3 (Lag-3) Protein Plus Pembrolizumab In Patients With Metastatic Melanoma, Victoria Atkinson, Adnan Khattak, Andrew Haydon, Melissa Eastgate, Amitesh Roy, Prashanth Prithviraj, Christian Mueller, Chrystelle Brignone, Frederic Triebel Jan 2020

Eftilagimod Alpha, A Soluble Lymphocyte Activation Gene-3 (Lag-3) Protein Plus Pembrolizumab In Patients With Metastatic Melanoma, Victoria Atkinson, Adnan Khattak, Andrew Haydon, Melissa Eastgate, Amitesh Roy, Prashanth Prithviraj, Christian Mueller, Chrystelle Brignone, Frederic Triebel

Research outputs 2014 to 2021

© Author(s) (or their employer(s)) 2020. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ. BACKGROUND: To evaluate the safety, tolerability, pharmacokinetics and pharmacodynamics of eftilagimod alpha (efti), a soluble lymphocyte activation gene-3 protein, in combination with the programmed cell death-1 (PD-1) antagonist pembrolizumab. METHODS: The study was divided into two parts; parts A and B, where part A was the dose escalation part and part B was an extension part of the study. Patients with metastatic melanoma were treated with efti plus the standard dose of pembrolizumab. Blood samples were assayed to determine …


Active And Passive Joint Position Sense On Healthy Hips, Julianna J. Johnson Jan 2020

Active And Passive Joint Position Sense On Healthy Hips, Julianna J. Johnson

WWU Graduate School Collection

Hip proprioception has been tested on various populations, but there is limited research on healthy young adults. Primary assessments of proprioception for hip have been on joint position sense (JPS), but fewer studies have accomplished this in an unconstraint testing apparatus with angular repositioning tasks. Purpose of this study was to examine effects of active and passive repositioning on hip JPS in healthy young adults. It was hypothesized that active JPS error scores would be lower compared to passive JPS error scores. There was a total of 15 subjects in the study. Digitization of anatomical landmarks were used to create …


The Influence Of A Slow-Breathing Protocol On Heart Rate And Blood Pressure From Exercise In Moderately Trained Females, Emily L. Zumbro, Greg A. Ryan, Stephen J. Rossi, John L. Dobson Apr 2019

The Influence Of A Slow-Breathing Protocol On Heart Rate And Blood Pressure From Exercise In Moderately Trained Females, Emily L. Zumbro, Greg A. Ryan, Stephen J. Rossi, John L. Dobson

International Journal of Exercise Science

International Journal of Exercise Science 12(2): 714-725, 2019. Heart rate recovery (HRR) and blood pressure recovery (BPR) from exercise are both important indicators of health and fitness and are strongly associated with cardiovascular disease. The purpose of this study was to compare the effects of a slow-breathing technique, upright passive recovery (PASS), and active recovery (ACT) on HRR and BPR from exercise. Nine moderately trained, college-aged (20.22 ± 0.97 yrs) female participants cycled three times on an ergometer for 15 mins at 70% of their heart rate maximum (HRmax), each of which was followed by one of three …


Effects Of Evidence-Based Materials And Access To Local Resources On Physical Activity During Pregnancy, Kolbi Edens Apr 2019

Effects Of Evidence-Based Materials And Access To Local Resources On Physical Activity During Pregnancy, Kolbi Edens

Masters Theses & Specialist Projects

Physical activity (PA) during pregnancy has been shown to be safe and effective for improving maternal and infant health; however, only 23% of pregnant women exercise in accordance with guidelines. PURPOSE: To determine if the distribution of evidence-based educational resources as well as access to community resources will increase PA levels as well as knowledge/beliefs about PA during pregnancy. METHODS: Participants (8-12 weeks) completed assessments concerning their activity levels, as well as knowledge/beliefs regarding PA, during pregnancy. Next, participants were randomly assigned to either an intervention (IG) or control group (CG). The IG received educational information regarding PA during pregnancy, …


Heart Rate Recovery And Blood Pressure Recovery Influenced By A Slow-Breathing Protocol After Exercise In Moderately Trained Females, Emily Layne Zumbro Jan 2017

Heart Rate Recovery And Blood Pressure Recovery Influenced By A Slow-Breathing Protocol After Exercise In Moderately Trained Females, Emily Layne Zumbro

Electronic Theses and Dissertations

Heart rate (HR) and blood pressure (BP) increases in order to meet metabolic demands as a result of exercise primarily through way of the sympathetic nervous system (SNS) and parasympathetic nervous system (PNS). This study aimed to build on previous research in finding the best method to rapidly decrease HR and BP after exercise during the recovery period. PURPOSE: The purpose of this study was to determine the effectiveness of a breathing technique on HRR and BPR within a healthy female population during an exercise recovery period compared to active recovery and upright passive recovery. METHODS: Nine moderately trained female …


Validation Of Maximal Heart Rate Prediction Equations Based On Sex And Physical Activity Status, Stephen J. Roy, J.L. Mccrory Oct 2015

Validation Of Maximal Heart Rate Prediction Equations Based On Sex And Physical Activity Status, Stephen J. Roy, J.L. Mccrory

International Journal of Exercise Science

International Journal of Exercise Science 8(4): 318-330, 2015. The purpose of the study was to determine if measured maximal heart rate (HRmax) was affected by sex or aerobic training status, and to determine the accuracy of three common clinical age-prediction maximal heart rate regression equations used to predict HRmax: HRmax = 220 – age, HRmax = 226 – age, and HRmax = 208 – (0.7 ∙ age). Fifty-two participants in total, 30 of which were in the active group (15 M, 15 F) and 22 subjects in the sedentary group (9 M, …


Active Versus Passive Control Of Arm Swing: Implication Of The Restriction Of Pelvis Rotation During Human Locomotion, Stephen Paul Canton Jan 2015

Active Versus Passive Control Of Arm Swing: Implication Of The Restriction Of Pelvis Rotation During Human Locomotion, Stephen Paul Canton

LSU Master's Theses

To date, it remains unclear how passive dynamics and active neural control contribute to arm swing during human locomotion. The passive hypothesis attributes arm swing to the passive transfer of energy from the legs to the arms via biomechanical linkages, while the active hypothesis states that arm swing is actively driven by muscles via neural mechanisms. The present study aims to investigate this phenomenon further by disrupting the biomechanical linkages, thereby directly challenging the passive hypothesis. Ten healthy individuals walked on a treadmill with and without an apparatus that constrained pelvis rotation at 3 different speeds (2 mph, 3 mph, …


Bilateral Vestibular Loss In Cats Leads To Active Destabilization Of Balance During Pitch And Roll Rotations Of The Support Surface, Jane Macpherson, Dirk Everaert, Paul Stapley, Lena Ting Jan 2013

Bilateral Vestibular Loss In Cats Leads To Active Destabilization Of Balance During Pitch And Roll Rotations Of The Support Surface, Jane Macpherson, Dirk Everaert, Paul Stapley, Lena Ting

Dr Paul J Stapley

Although the balance difficulties accompanying vestibular loss are well known, the underlying cause remains unclear. We examined the role of vestibular inputs in the automatic postural response (APR) to pitch and roll rotations of the support surface in freely standing cats before and in the first week after bilateral labyrinthectomy. Support surface rotations accelerate the body center of mass toward the downhill side. The normal APR consists of inhibition in the extensors of the uphill limbs and excitation in the downhill limbs to decelerate the body and maintain the alignment of the limbs with respect to earth-vertical. After vestibular lesion, …


Bilateral Vestibular Loss Leads To Active Destabilization Of Balance During Voluntary Head Turns In The Standing Cat, Paul Stapley, Lena Ting, Chen Kuifu, Dirk Everaert, Jane Macpherson Jan 2013

Bilateral Vestibular Loss Leads To Active Destabilization Of Balance During Voluntary Head Turns In The Standing Cat, Paul Stapley, Lena Ting, Chen Kuifu, Dirk Everaert, Jane Macpherson

Dr Paul J Stapley

The purpose of this study was to determine the source of postural instability in labyrinthectomized cats during lateral head turns. Cats were trained to maintain the head in a forward orientation and then perform a rapid, large-amplitude head turn to left or right in yaw, while standing freely on a force platform. Head turns were biomechanically complex with the primary movement in the yaw plane accompanied by an ipsilateral ear-down roll and nose-down pitch. Cats used a strategy of pushing off by activating extensors of the contralateral forelimb while using all four limbs to produce a rotational moment of force …


An Epididymal Form Of Cauxin, A Carboxylesterase-Like Enzyme, Is Present And Active In Mammalian Male Reproductive Fluids, Heath W. Ecroyd, Maya Belghazi, Jl Dacheux, M Miyazaki, T Yamashita, Jl Gatti Dec 2011

An Epididymal Form Of Cauxin, A Carboxylesterase-Like Enzyme, Is Present And Active In Mammalian Male Reproductive Fluids, Heath W. Ecroyd, Maya Belghazi, Jl Dacheux, M Miyazaki, T Yamashita, Jl Gatti

Heath Ecroyd

Mass spectrometric analysis of a prion protein (PrP)-containing complex isolated from ram cauda epididymal fluid revealed a protein that showed homology to a carboxylesterase-like protein previously identified in cat urine (cauxin). Using anticauxin antibodies, immunoreactive bands were detected in corpus and cauda epididymal fluid from all mammals tested (ram, boar, mouse, and cat). In the ram, the protein was also present in seminal fluid but not found to be associated with sperm. The bands reacting with the anti-cauxin antibody coincided with those having esterase activity in a zymographic assay and its levels paralleled the esterase activity of native epididymal fluids. …


The Relationship Between Within-Day Energy Balance And Menstruation In Active Females, Alexandra J. Friel Aug 2010

The Relationship Between Within-Day Energy Balance And Menstruation In Active Females, Alexandra J. Friel

Nutrition Theses

Background: Past studies suggest that inadequate energy intake (EI) is directly related to menstrual dysfunction (MD) in active females. Inadequate EI causes activation of the hypothalamic-pituitary-adrenal axis, disrupting the normal hormonal signaling of reproductive cycling and resulting in MD. However, studies have also demonstrated similar EI in athletes, but with different menstrual function. Traditionally, energy balance has been evaluated in 24-hour time periods. Recent research suggests there is benefit to analyzing energy balance at smaller intervals to better address physiologic response in real time. It is possible that women who meet their daily EI needs could still, therefore, experience MD …


The Effects Of Exercise On Acute Energy Balance And Macronutrient Intake, Emily N. Jokisch May 2010

The Effects Of Exercise On Acute Energy Balance And Macronutrient Intake, Emily N. Jokisch

Masters Theses

This investigation examined acute energy compensation and macronutrient intake in habitually active and sedentary, college-aged males, following an exercise session as compared to a resting (control) session, to see if habitually active males compensate intake better to an energy deficit incurred by exercise, than sedentary males.

Participants were males, aged 18-30 years, of a normal percent body fat and body mass index, and exercised < 60 min per week (sedentary) or > 150 min per week (habitually active). Participants came in for two sessions: 1) 45 minutes of resting (control) and then eating an ad libitum meal; and 2) riding a cycle ergometer for 45 minutes (exercise) and …


Double Standards For Community Sports: Promoting Active Lifestyles But Unhealthy Diets, Bridget P. Kelly, Kathy Chapman, Lesley King, Louise L. Hardy, Louise Farrell Jan 2008

Double Standards For Community Sports: Promoting Active Lifestyles But Unhealthy Diets, Bridget P. Kelly, Kathy Chapman, Lesley King, Louise L. Hardy, Louise Farrell

Faculty of Health and Behavioural Sciences - Papers (Archive)

Issue addressed: Overweight and obesity in Australia is an emerging health concern. Obesity prevention initiatives must consider both physical activity and nutrition to be effective. Community sports venues have the capacity to promote healthy lifestyles through physical activity as well as healthy food choices. Methods: A telephone survey was conducted on parents of children aged 5-17 years in NSW to determine the nature of food and beverages purchased by children at community sporting venues and to determine parent’s perception of the role that government should play in regulating the types of food and beverages sold at these outlets. Results: The …


An Epididymal Form Of Cauxin, A Carboxylesterase-Like Enzyme, Is Present And Active In Mammalian Male Reproductive Fluids, Heath W. Ecroyd, Maya Belghazi, Jl Dacheux, M Miyazaki, T Yamashita, Jl Gatti Jan 2006

An Epididymal Form Of Cauxin, A Carboxylesterase-Like Enzyme, Is Present And Active In Mammalian Male Reproductive Fluids, Heath W. Ecroyd, Maya Belghazi, Jl Dacheux, M Miyazaki, T Yamashita, Jl Gatti

Faculty of Science - Papers (Archive)

Mass spectrometric analysis of a prion protein (PrP)-containing complex isolated from ram cauda epididymal fluid revealed a protein that showed homology to a carboxylesterase-like protein previously identified in cat urine (cauxin). Using anticauxin antibodies, immunoreactive bands were detected in corpus and cauda epididymal fluid from all mammals tested (ram, boar, mouse, and cat). In the ram, the protein was also present in seminal fluid but not found to be associated with sperm. The bands reacting with the anti-cauxin antibody coincided with those having esterase activity in a zymographic assay and its levels paralleled the esterase activity of native epididymal fluids. …


Ec04-442 Adjusting Recipes To Meet Dietary Guidelines, Georgia Jones, Julie A. Albrecht, Linda S. Boeckner Jan 2004

Ec04-442 Adjusting Recipes To Meet Dietary Guidelines, Georgia Jones, Julie A. Albrecht, Linda S. Boeckner

University of Nebraska-Lincoln Extension: Historical Materials

You may be one of millions of Americans trying to make some eating adjustments and finding time-honored traditions and habits get in the way. Possible and acceptable changes take time and consideration and should focus on the Dietary Guidelines for Americans.

This Extension Circular provides tips to help make the Dietary Guidelines work for you by adjusting recipes for some of the foods you prepare at home.


February: Becoming More Active, Utah State University Extension Jan 2002

February: Becoming More Active, Utah State University Extension

All Archived Publications

No abstract provided.


Induction Of Integral Membrane Pam Expression In Att-20 Cells Alters The Storage And Trafficking Of Pomc And Pc1, Giuseppe D. Ciccotosto, Martin R. Schiller, Betty A. Eipper, Richard E. Mains Feb 1999

Induction Of Integral Membrane Pam Expression In Att-20 Cells Alters The Storage And Trafficking Of Pomc And Pc1, Giuseppe D. Ciccotosto, Martin R. Schiller, Betty A. Eipper, Richard E. Mains

Life Sciences Faculty Research

Peptidylglycine alpha-amidating monooxygenase (PAM) is an essential enzyme that catalyzes the COOH-terminal amidation of many neuroendocrine peptides. The bifunctional PAM protein contains an NH2-terminal monooxygenase (PHM) domain followed by a lyase (PAL) domain and a transmembrane domain. The cytosolic tail of PAM interacts with proteins that can affect cytoskeletal organization. A reverse tetracycline-regulated inducible expression system was used to construct an AtT-20 corticotrope cell line capable of inducible PAM-1 expression. Upon induction, cells displayed a time- and dose-dependent increase in enzyme activity, PAM mRNA, and protein. Induction of increased PAM-1 expression produced graded changes in PAM-1 metabolism. Increased expression of …


G83-651 Nebraska's Solar Heated Modified-Open-Front Swine Nursery, Michael F. Kocher, Gerald R. Bodman, C.J. Kisling-Crouch Jan 1983

G83-651 Nebraska's Solar Heated Modified-Open-Front Swine Nursery, Michael F. Kocher, Gerald R. Bodman, C.J. Kisling-Crouch

University of Nebraska-Lincoln Extension: Historical Materials

This NebGuide discusses the design features of this unique swine nursery, including ventilation, heating and energy conservation factors, and manure handling systems.

A warm environment is essential for young pigs. High fuel costs and the practice of heating entire buildings brought about the design and testing of solar heated nurseries on several farms.