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Full-Text Articles in Life Sciences
The Role Of Fgfr4 In Trigeminal Placode Cell Development, Stephanie Beth Reynolds
The Role Of Fgfr4 In Trigeminal Placode Cell Development, Stephanie Beth Reynolds
Theses and Dissertations
In vertebrate embryos, the ophthalmic trigeminal (opV) placode contributes sensory neurons to the trigeminal ganglion during development of the peripheral nervous system. FGFR4 is expressed transiently in the trigeminal placode as cells undergo an epithelial-mesenchymal transition and begin to migrate toward the condensing ganglion. Because of the restricted spatiotemporal expression of FGFR4 in the opV placode, it was hypothesized that FGFR4 is necessary for the process of epithelial-mesenchymal transition in the opV placode. Using electroporation, an FGFR4 inhibitory gene construct was introduced into 6—10 somite stage chick embryos. This secreted inhibitory form of the FGFR4 gene blocked endogenous FGFR4 signaling, …
In Vitro Effects Of Some Antibiotics On Glutathione Reductase Obtained From Chicken Liver, Hülya Demi̇r, Mustafa Erat, Hali̇s Şaki̇roğlu
In Vitro Effects Of Some Antibiotics On Glutathione Reductase Obtained From Chicken Liver, Hülya Demi̇r, Mustafa Erat, Hali̇s Şaki̇roğlu
Turkish Journal of Veterinary & Animal Sciences
Glutathione reductase (GR) is important in maintaining high levels of reduced glutathione in cells. The enzyme is inhibited by some drugs used in antimicrobial chemotherapy. The effects of some antibiotics on GR activity were investigated in this study. At first, the enzyme, having a specific activity of 88.28 EU/mg proteins, was purified 1636-fold with a yield of 35%. Purity of the enzyme was checked by means of sodium dodecyl sulfate polyacrylamide gel electrophoresis (SDS-PAGE). Activity of the enzyme was determined spectrophotometrically at 340 nm and in vitro effects of ofloxacin, levofloxacin, cefazolin, and cefepime were determined. The antibiotics used in …
Alterations To Lipid Parameters In Response To Fig Tree (Ficus Carica) Leaf Extract In Chicken Liver Slices, Farzad Asadi, Malihe Pourkabir, Robin Maclaren, Ali Shahriari
Alterations To Lipid Parameters In Response To Fig Tree (Ficus Carica) Leaf Extract In Chicken Liver Slices, Farzad Asadi, Malihe Pourkabir, Robin Maclaren, Ali Shahriari
Turkish Journal of Veterinary & Animal Sciences
Lipid storage, particularly in the abdominal cavity, is a major concern in poultry breeding because it affects the net meat yield. The major contributors to lipid storage in the abdominal cavity are hepatic fatty acid synthesis and VLDL secretion. These factors are strongly correlated with the body fatness in the chicken. The aim of our study was to determine if a traditional food supplement, the extract from fig tree leaves (fig tree leaf extract (FTE)), can be used to decrease hepatic triglyceride (TG) content and secretion of TG and cholesterol (TC) from the liver. Livers from 8-week-old roosters (n = …