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Full-Text Articles in Life Sciences
Toxicity, Biotransformation, And Mode Of Action Of Arsenic In Two Freshwater Microalgae (Chlorella Sp. And Monoraphidium Arcuatum), Jacqueline L. Levy, Jennifer L. Stauber, Merrin S. Adams, William A. Maher, Jason K. Kirby, Dianne F. Jolley
Toxicity, Biotransformation, And Mode Of Action Of Arsenic In Two Freshwater Microalgae (Chlorella Sp. And Monoraphidium Arcuatum), Jacqueline L. Levy, Jennifer L. Stauber, Merrin S. Adams, William A. Maher, Jason K. Kirby, Dianne F. Jolley
Faculty of Science - Papers (Archive)
The toxicity of As(V) and As(III) to two axenic tropical 15 freshwater microalgae, Chlorella sp. and Monoraphidium arcuatum, was determined using 72-h growth rate inhibition bioassays. Both organisms were tolerant to As(III) (72-h IC50, concentration to cause 50% inhibition of growth, of 25 and 15 mg As(III)/L, respectively). Chlorella sp. was also tolerant to As(V) with no effect on growth rate over 72 h at concentrations up to 0.8 mg/L (72-h IC50 of 25 mg As(V)/L). M. arcuatum was more sensitive to As(V) (72-h IC50 of 0.25 mg As(V)/L). An increase in phosphate in the growth medium (0.15 to 1.5 …
The Acute Phase Protein Haptoglobin Is A Mammalian Extracellular Chaperone With An Action Similar To Clusterin, Justin Yerbury, Mark S Rybchyn, Simon B Easterbrook-Smith, C. Henriques, Mark Wilson
The Acute Phase Protein Haptoglobin Is A Mammalian Extracellular Chaperone With An Action Similar To Clusterin, Justin Yerbury, Mark S Rybchyn, Simon B Easterbrook-Smith, C. Henriques, Mark Wilson
Mark R Wilson
Haptoglobin (Hp) is an acidic glycoprotein present in most body fluids of humans and other mammals. Although the functions of Hp are not yet fully understood, the available evidence indicates that it is likely to play an important role in suppressing inflammatory responses. Some earlier work suggested that Hp might be a newly identified member of a small group of extracellular chaperones found at significant levels in human body fluids. Previously, the only well-characterized member of this group was clusterin, which shares functional similarities with the small heat-shock proteins. We report here that Hp specifically inhibited the precipitation of a …