Life Sciences Commons^™

Proliferation Zones In The Salmon Telencephalon And Evidence For Environmental Influence On Proliferation Rate, Sean C. Lema, Mark J. Hodges, Michael P. Marchetti, Gabrielle A. Nevitt

Biological Sciences

Cell proliferation occurs in the brain of fish throughout life. This mitotic activity contributes new neurons to some brain subdivisions, suggesting potential for plasticity in neural development. Recently we found that the telencephalon in salmonids (salmon, trout) is significantly reduced in fish reared in hatcheries compared to wild fish, and that these differences resulted in part from rearing conditions. Here, we describe localized areas of cell proliferation in the telencephalon of juvenile coho salmon (Oncorhynchus kisutch) and begin to explore whether mitotic activity in these areas is sensitive to environmental conditions. Using the 5-bromo-2'-deoxyuridine (BrdU) cell birthdating technique, …