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Full-Text Articles in Life Sciences
Intraocular Lens Implant Image Quality: The Optico-Retinal Interface, David D. Bogorad
Intraocular Lens Implant Image Quality: The Optico-Retinal Interface, David D. Bogorad
Henry Ford Hospital Medical Journal
Improvements in intraocular lens implants during the past ten years have revolutionized cataract surgery. Both anterior and posterior chamber lenses are currently in wide use, but the optical superiority of the posterior chamber location has yet to be demonstrated. To do so, a more detailed analysis is required of visual function than is clinically routine. Also required is appreciation that the retina is an integral part of the eye's optical system because of its directional characteristics, which are known as the Stiles-Crawford effect. The optical quality of the pseudophakic eye is affected by the optics of the implant, its centration, …
Glaucoma Filtration Surgery: A Personal Review, Saul Sugar
Glaucoma Filtration Surgery: A Personal Review, Saul Sugar
Henry Ford Hospital Medical Journal
No abstract provided.
Immunocytologic Methods In The Diagnosis Of Orbital Tumors, David M. Reifler, Sudha R. Kini, John S. Kennerdell, Andrew Dekker, Leslie J. Fisher
Immunocytologic Methods In The Diagnosis Of Orbital Tumors, David M. Reifler, Sudha R. Kini, John S. Kennerdell, Andrew Dekker, Leslie J. Fisher
Henry Ford Hospital Medical Journal
The pathologic diagnosis was supported or confirmed in three out of four cases that had an adequate cytologic specimen. The results demonstrate that adjunctive immunocytologic techniques can be used in combination with fine-needle aspiration for a variety of orbital tumors. The pathologic diagnosis was supported or confirmed in three out of four cases that had an adequate cytologic specimen. The results demonstrate that adjunctive immunocytologic techniques can be used in combination with fine-needle aspiration for a variety of orbital tumors.
Some Unusual Foreign Bodies In The Anterior Segment Of The Eye And The Orbit, Saul Sugar
Some Unusual Foreign Bodies In The Anterior Segment Of The Eye And The Orbit, Saul Sugar
Henry Ford Hospital Medical Journal
No abstract provided.
Malnutrition And Length Of Stay - A Relationship?, Marvin D. Anderson, Gladys Collins, Gloria Davis, Brack A. Bivins
Malnutrition And Length Of Stay - A Relationship?, Marvin D. Anderson, Gladys Collins, Gloria Davis, Brack A. Bivins
Henry Ford Hospital Medical Journal
The admission nutrition status of 135 consecutive general medical patients admitted to a single nursing unit was evaluated using a simple questionnaire and available laboratory studies. A statistical analysis of the data obtained indicates that prolonged length of stay may be related to admission nutritional status.
Childhood Lead Poisoning, Raj P. Warrier, Jan Waisanen, Sam R. Kottamasu, Sayeed Sultana, K. Ratnakar Kini, William L. Kestenberg, John Strauthers, Craig Foreback
Childhood Lead Poisoning, Raj P. Warrier, Jan Waisanen, Sam R. Kottamasu, Sayeed Sultana, K. Ratnakar Kini, William L. Kestenberg, John Strauthers, Craig Foreback
Henry Ford Hospital Medical Journal
Although lead encephalopathy is rare, lead intoxication continues to be a significant problem in Detroit. Neuropsychological effects may occur even at low levels of lead. Since treatment of lead poisoning consists of a painful series of injections, it is imperative that more attention be given to the prevention of this disease. To confirm the magnitude of the problems, our experience with lead poisoning during a three-year period at Henry Ford Hospital's Pediatric Department is reviewed.
Primary Hyperparathyroidism: Changing Patterns In Presentation And Treatment Decisions In The Eighties, D. Sudhaker Rao
Primary Hyperparathyroidism: Changing Patterns In Presentation And Treatment Decisions In The Eighties, D. Sudhaker Rao
Henry Ford Hospital Medical Journal
No abstract provided.
Dermatomyositis Complicated By Thrombotic Thrombocytopenic Purpura, Maria A. Sawdyk, Jeffrey Jundt
Dermatomyositis Complicated By Thrombotic Thrombocytopenic Purpura, Maria A. Sawdyk, Jeffrey Jundt
Henry Ford Hospital Medical Journal
A 65-year-old woman who had a documented history of dermatomyositis was hospitalized for evaluation of a syncopal attack. During the course of her stay, she experienced progressive neurologic dysfunction, hemolytic anemia, and thrombocytopenia. A clinical diagnosis of thrombotic thrombocytopenia purpura (TTP) was made, and therapy was initiated with glucocorticoids, plasmapheresis, plasma infusion, and antiplatelet medication. The pathogenesis of TTP has not been cleady elucidated. However, reports in the literature have postulated immune damage of the endothelium with demonstration of IgM and complement deposits as the origin of the condition. Further, there are reported cases of TTP associated with collagen disorders …
Clinical Trials: Ii. Randomization And Sample Size, Barbara Tilley, Anthony Schork
Clinical Trials: Ii. Randomization And Sample Size, Barbara Tilley, Anthony Schork
Henry Ford Hospital Medical Journal
This second in a series of articles focuses on clinical trials. Information is provided on determining sample size and on methods of randomization including simple and single- and double-consent randomization, and blocked, stratified, and adaptive procedures to randomize patients to a study group.
Hereditary Sclerocornea, David Barsky, Steven P. Dunn
Hereditary Sclerocornea, David Barsky, Steven P. Dunn
Henry Ford Hospital Medical Journal
A rare case of total hereditary sclerocornea is presented along with clinical history, histopathology, and a review of the possible pathogenesis and current literature on the subject. It is quite possible that imperfect cleavage of the anterior chamber angle may be the predisposing factor in scleralization of the cornea due to a failure of neural crest cell differentiation. If surgical intervention to correct for the corneal opacification is indicated, corneal transplantation should be performed as soon as possible after birth, similar to the indications for removal of dense congenital cataracts to avoid deprivation amblyopia.
Orbital Metastasis With Enophthalmos: A Review Of The Literature, David M. Reifler
Orbital Metastasis With Enophthalmos: A Review Of The Literature, David M. Reifler
Henry Ford Hospital Medical Journal
Orbital metastasis is associated with enophthalmos in up to one third of all cases. After analyzing the clinical and pathologic features In 25 reported cases of enophthalmic orbital metastasis, the condition was found to almost exclusively affect females, usually in the 60 to 70 age group. The right orbit was the most commonly affected. The primary lesion was located in the breast in 19 (76%) cases and in the abdomen in 6 (24%) cases. In one third of the cases, the manifestations of the orbital metastasis were recognized before diagnosing the primary lesion. The most common presenting features were diplopia …
Editorial: Corneal Stability With Rigid Gas Permeable Lens Refitting, Robert J. Crossen
Editorial: Corneal Stability With Rigid Gas Permeable Lens Refitting, Robert J. Crossen
Henry Ford Hospital Medical Journal
No abstract provided.
The Pseudo-Leukocyte-Specific/Nuclear Membrane Antinuclear Antibody Pattern: A Puzzle, Thomas K. Burnham
The Pseudo-Leukocyte-Specific/Nuclear Membrane Antinuclear Antibody Pattern: A Puzzle, Thomas K. Burnham
Henry Ford Hospital Medical Journal
We report an antinuclear antibody (ANA) pattern—the pseudo-leukocyte-specific/nuclear membrane (PLS/NM) ANA pattern—that is puzzling because it usually reacts with only a few cells on human spleen imprints but with most epidermal and numerous dermal nuclei of normal human skin sections. The designation "pseudo-leukocyte-specific" was chosen because it is generally seen in only a few nuclei on human spleen imprints, thereby resembling the true leukocyte-specific ANA pattern. A few small round nuclei fluoresce homogeneously, surrounded by a bright wall, suggesting nuclear membrane (NM) fluorescence. The term "nuclear membrane" was added to the name because the NM appearance is even more prominent …
Evaluation Of Peutz-Jeghers Syndrome In A Family, Kayhan Ozkan
Evaluation Of Peutz-Jeghers Syndrome In A Family, Kayhan Ozkan
Henry Ford Hospital Medical Journal
Five cases of Peutz-Jeghers syndrome in one family have been studied, and a review of the history and features of the syndrome are presented. This syndrome was detected in four of six siblings and in the father. Three family members underwent surgery after small-bowel obstruction was diagnosed. A gastric polyp was removed from a fourth family member. Rectal bleeding dominated the clinical picture in two patients. Colonic polyps were also found in the three patients who had small-bowel polyps. One of the four affected siblings had mucocutaneous pigmentation, but no evidence of intestinal polyps was detected. The five affected family …
Enteroclysis For The Examination Of The Small Bowel, Robert D. Halpert, Peter J. Feczko, Cathrine E. Keller, Judith Iorio
Enteroclysis For The Examination Of The Small Bowel, Robert D. Halpert, Peter J. Feczko, Cathrine E. Keller, Judith Iorio
Henry Ford Hospital Medical Journal
Detailed evaluation of the small bowel is difficult because of its inaccessibility. The small bowel follow-through examination using barium, has low diagnostic sensitivity. Enteroclysis, the injection of contrast material through a duodenal or jejunal tube, offers a newer and highly sensitive method of radiological evaluation. Our paper describes the technique, clinical indications, and side effects of enteroclysis.
Diagnostic Imaging In The 1980s: Quo Vadis?, James H. Thrall, Robert D. Halpert
Diagnostic Imaging In The 1980s: Quo Vadis?, James H. Thrall, Robert D. Halpert
Henry Ford Hospital Medical Journal
No abstract provided.
Computed Tomographic And Sonographic Characterizations Of Central Nervous System Masses, Beatrice L. Madrazo, William P. Sanders, Bharat Mehta, Manuel Dujovny, Michael A. Sandler, David P. Chason, Jacob L. Chason, James I. Ausman
Computed Tomographic And Sonographic Characterizations Of Central Nervous System Masses, Beatrice L. Madrazo, William P. Sanders, Bharat Mehta, Manuel Dujovny, Michael A. Sandler, David P. Chason, Jacob L. Chason, James I. Ausman
Henry Ford Hospital Medical Journal
We present our experience with 15 central nervous system masses evaluated preoperatively with computed tomography and by intraoperative sonography. Cysts were seen as sharply circumscribed, thin-walled masses, near water density by computed tomography, and echo-free by sonography. Inflammatory masses were well demarcated by tomography with areas of edema and ring enhancement but were poorly marginated and variable in appearance by sonography. Primary brain tumors presented as round, solid or complex masses best evaluated by intraoperative sonography in those cases where poor contrast enhancement resulted in limited characterization of the mass by computed tomography. Our experience suggests a very high degree …
The Tube Esophagogram In Cases Of Possible Esophageal Stricture: A Technical Note, Lawrence M. Dubin, Robert D. Halpert, Peter J. Feczko, Sambasiva R. Kottamasu
The Tube Esophagogram In Cases Of Possible Esophageal Stricture: A Technical Note, Lawrence M. Dubin, Robert D. Halpert, Peter J. Feczko, Sambasiva R. Kottamasu
Henry Ford Hospital Medical Journal
Esophageal strictures can occasionally be underdiagnosed because of the failure to achieve complete and consistent distention of the esophagus. When tube esophagography is performed, a small catheter is positioned in the patient's esophagus, and air is insufflated after the patient drinks barium. This produces maximum, uniform distention of the esophagus with little patient discomfort. This technique is valuable in demonstrating mild or subtle strictures, improving mucosal detail, and evaluating areas suggestive of stricture on routine radiographs.
Mammography: Still The Imaging Standard, Cathrine E. Keller, A. Christine Watt
Mammography: Still The Imaging Standard, Cathrine E. Keller, A. Christine Watt
Henry Ford Hospital Medical Journal
Breast carcinoma is the leading cause of cancer death in women in the United States. Recent technological advances have resulted in multiple imaging methods designed to improve the detection of breast cancer. These imaging methods are discussed. Mammography remains the most accurate imaging method used to evaluate the breast. Automated waterpath whole-breast ultrasound is the most useful adjunctive examination to mammography at the present time.
Cerebral Angiography In Posterior Fossa Revascularization, Roushdy S. Boulos, Suresh Patel, Bharat Mehta, Clifford Jack
Cerebral Angiography In Posterior Fossa Revascularization, Roushdy S. Boulos, Suresh Patel, Bharat Mehta, Clifford Jack
Henry Ford Hospital Medical Journal
With advances in microsurgical techniques and refinement of cerebral angiography, many new surgical approaches for the treatment of vertebrobasilar insufficiency (VBI) have been developed. Detailed selective cerebral angiography is essential for confirming the clinical diagnosis, for demonstrating the exact anatomical and topographical vascular pathology, and for deciding on the best surgical procedure. Angiography is recommended to evaluate treated patients both in the early and late postoperative periods. It is an essential element of any future randomized study to assess the value of surgical vs medical treatment of patients with VBI. The benefits of cerebral angiography far outweigh the small risk …
The Incidence Of Calculi In Focal Nonshadowing Echogenicity In The Gallbladder, Michael A. Sandler, Eileen M. Biunno, Martin L. Gross, Beatrice L. Madrazo
The Incidence Of Calculi In Focal Nonshadowing Echogenicity In The Gallbladder, Michael A. Sandler, Eileen M. Biunno, Martin L. Gross, Beatrice L. Madrazo
Henry Ford Hospital Medical Journal
Sonography is valuable in the accurate diagnosis of gallstones. All but the smallest stones attenuate sound, a phenomenon known as acoustic shadowing. However, when small focal nonshadowing opacities are present, the diagnostic question is whether they represent small calculi. In a four-year review of sonographic studies performed at Henry Ford Hospital, 12 patients in whom this sonographic finding was present underwent cholecystectomies, and seven had calculi (58%). If the presence of gallstones is the factor that will determine whether surgery will be performed, we recommend a repeat examination to confirm the presence of the focal opacities and to elicit acoustic …
Digital Subtraction Angiography Of The Abdomen: Henry Ford Hospital Experience, Rajinder P. Sharma, Gary A. Krasicky, Matthew W. Burke, Sadasiva B. Jampala, P. C. Shetty, Dennis P. Swanson
Digital Subtraction Angiography Of The Abdomen: Henry Ford Hospital Experience, Rajinder P. Sharma, Gary A. Krasicky, Matthew W. Burke, Sadasiva B. Jampala, P. C. Shetty, Dennis P. Swanson
Henry Ford Hospital Medical Journal
Digital subtraction angiography (DSA) produces high-contrast digital images of the abdominal vasculature with minimum patient discomfort. We summarize the Henry Ford Hospital experience with DSA in evaluating various abdominal vascular disorders. The methods and merits of intravenous and intraarterial approaches, the advantages and disadvantages compared with those of conventional angiography, and the current limitations of DSA are discussed.
Nuclear Magnetic Resonance: Current And Future Clinical Applications, Jerry W. Froelich, David O. Hearshen, Robert D. Halpert, Suresh Patel
Nuclear Magnetic Resonance: Current And Future Clinical Applications, Jerry W. Froelich, David O. Hearshen, Robert D. Halpert, Suresh Patel
Henry Ford Hospital Medical Journal
Nuclear magnetic resonance has evolved from a laboratory analytical tool to become a rapidly developing discipline in clinical medicine. We present a brief historical overview, an introduction to the basic principles of the phenomenon, and a statement of the current status of clinical imaging. We have elected to use the traditional terminology nuclear magnetic resonance to refer to the imaging component of the field rather than the American College of Radiology (ACR) modification magnetic resonance. We do this out of respect for the founders of the field.
Percutaneous Nephrolithotomy: Current Methods And The Henry Ford Hospital Experience, P. C. Shetty, Rajinder P. Sharma, Raymond H. Littleton, Gary A. Krasicky, Matthew W. Burke, Brian J. Miles, James H. Thrall, Joseph C. Cerny
Percutaneous Nephrolithotomy: Current Methods And The Henry Ford Hospital Experience, P. C. Shetty, Rajinder P. Sharma, Raymond H. Littleton, Gary A. Krasicky, Matthew W. Burke, Brian J. Miles, James H. Thrall, Joseph C. Cerny
Henry Ford Hospital Medical Journal
The combined radiologic/urologic approach to percutaneous renal stone extraction has been practiced at Henry Ford Hospital since November of 1982. This article describes the current methodology and reviews our experience in performing 121 percutaneous nephrolithotomies (PCNL). We conclude that PCNL is a safe, reliable, and cost-effective alternative to open nephrolithotomy in most patients.
Current Concepts Of Metabolic Functional Imaging With Positron Emitters, John W. Keyes Jr.
Current Concepts Of Metabolic Functional Imaging With Positron Emitters, John W. Keyes Jr.
Henry Ford Hospital Medical Journal
Positron emitting radionuclides have unique properties that make them nearly ideal as radioactive tracers for in vivo metabolic studies. Using positron emission tomographic (PET) scanning and positron-labeled radiopharmaceuticals, one can study local glucose metabolism in tissues, blood flow, oxygen utilization, protein synthesis, and many other functions noninvasively in normal subjects and patients who have various diseases. A review of some of these techniques and the relative advantages and problems associated with the PET approach is presented.
Applications Of Magnetic Resonance Imaging In Clinical Urology, Barbara A. Demas, Hedvig Hricak
Applications Of Magnetic Resonance Imaging In Clinical Urology, Barbara A. Demas, Hedvig Hricak
Henry Ford Hospital Medical Journal
During the past two years, the value of magnetic resonance imaging (MRI) in the diagnosis and staging of a variety of urologic neoplasms has been demonstrated, and the ability of MRI to determine sites of renal obstruction and causes of posttransplant renal failure have been reported. Its excellent soft-tissue contrast resolution has allowed accurate delineation of regional anatomy in the kidney, prostate gland, urinary bladder, urethra, uterus, and vagina. The importance of MRI in the urologic diagnosis is expected to increase as clinical imaging systems become widely available.
Digital Radiography: A Review, David J. Kastan, Laurens V. Ackerman, Peter J. Feczko, Gordon H. Beute
Digital Radiography: A Review, David J. Kastan, Laurens V. Ackerman, Peter J. Feczko, Gordon H. Beute
Henry Ford Hospital Medical Journal
The fully digital radiology department remains a radiologist's dream. The technology necessary for implementation does not yet exist other than in prototype form. When the technology catches up with the radiologist's ideas, many new capabilities will exist. Electronically stored images will be available for viewing wherever a computer terminal exists. The problem of film loss would be nonexistent. Images could be quickly transmitted for interpretation via microwave networks to sites far removed from where they are acquired. Patient radiation exposure would decrease. Computers would help decrease perception errors and would assist in image interpretation. It may be ten years before …