Life Sciences Commons^™

Solubilization Of Acetylcholinestrerae From Subcellular Components Of Mammalian Brain Tissue, John E. Taylor

University of the Pacific Theses and Dissertations

Since all chemical and electrical input into the cell / occurs via its plasma membrane, many pharmacological agents and hormones initiate their effects by interacting with receptor sites on the plasma membrane or by passing through the cell membrane and interacting with other membranes within the cell. Generally, the precise mechanisms by which these events occur remain relatively unclear. It was thought for many years that the cell membrane was a relatively static structure which allowed molecules to enter the cell at a rate dependent upon their degree of lipid solubility. However, more recently an increasing body of evidence suggests …