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Theses/Dissertations

2021

University of Central Florida

Down syndrome

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Paternal Ages And Genetic Diseases And Congenital Anomalies, Neda Hamood Jan 2021

Paternal Ages And Genetic Diseases And Congenital Anomalies, Neda Hamood

Honors Undergraduate Theses

The purpose of this thesis is to investigate the link between advanced paternal ages (APA) (i.e., APA ≥ 35 years and APA ≥ 50 years) and genetic diseases and congenital anomalies. Currently, the relationship between both advanced paternal ages and genetic diseases and congenital anomalies remains unclear. However, there is room for improvement to systematically investigate the relationship between specific congenital anomalies in newborns and advanced paternal ages. More recently, the link between advanced paternal age (as opposed to existing studies analyzing advanced maternal age alone) and genetic diseases has been recognized by researchers, epidemiologists, and various health experts. Thus, …