Life Sciences Commons^™

Pparα L162v Underlies Variation In Serum Triglycerides And Subcutaneous Fat Volume In Young Males, Julieta Uthurralt, Heather Gordish-Dressman, Meg Bradbury, Carolina Tesi-Rocha, Joseph Devaney, Brennan Harmon, Erica K. Reeves, Cinzia Brandoli, Barbara C. Hansen, Richard L. Siep, Paul D. Thompson, Thomas B. Price, Theodore J. Angelopoulos, Priscilla M. Clarkson

Priscilla M. Clarkson

Background: Of the five sub-phenotypes defining metabolic syndrome, all are known to have strong genetic components (typically 50–80% of population variation). Studies defining genetic predispositions have typically focused on older populations with metabolic syndrome and/or type 2 diabetes. We hypothesized that the study of younger populations would mitigate many confounding variables, and allow us to better define genetic predisposition loci for metabolic syndrome. Methods: We studied 610 young adult volunteers (average age 24 yrs) for metabolic syndrome markers, and volumetric MRI of upper arm muscle, bone, and fat pre- and post-unilateral resistance training. Results: We found the PPARα L162V polymorphism …

Two-State Model Of Acto-Myosin Attachment-Detachment Predicts C-Process Of Sinusoidal Analysis, Bradley M. Palmer, Takeki Suzuki, Yuan Wang, William D. Barnes, Mark S. Miller, David W. Maughan

Mark S. Miller

The force response of activated striated muscle to length perturbations includes the so-called C-process, which has been considered the frequency domain representation of the fast single-exponential force decay after a length step (phases 1 and 2). The underlying molecular mechanisms of this phenomenon, however, are still the subject of various hypotheses. In this study, we derived analytical expressions and created a corresponding computer model to describe the consequences of independent acto-myosin cross-bridges characterized solely by 1), intermittent periods of attachment (t(att)) and detachment (t(det)), whose values are stochastically governed by independent probability density functions; and 2), a finite Hookian stiffness …

Mechanical Power And Efficiency Of Level Walking With Different Stride Rates, Brian R. Umberger, Philip E. Martin

Philip E. Martin

Walking humans prefer to use the stride rate that results in the lowest rate of metabolic energy expenditure. Mechanical power requirements have been suggested to underlie the metabolic response, but mechanical power is consistently reported to be minimal at stride rates 20–30% lower than preferred. This may be due to limitations in how total mechanical power has been computed, as well as a failure to account for the efficiency with which muscular work is done. We investigated how mechanical power and efficiency depend on stride rate in walking, with both quantities computed from the work done by the hip, knee …

Asana To America: The Advent Of Yoga In The West, M. Popovic, Don Morrow

Donald Morrow

No abstract provided.

Electromyographic Comparison Of A Stability Ball Crunch With A Traditional Crunch, Eric Sternlicht, Stuart Rugg, Larissa Fujii, Keri Tomomitsu, Matt Seki

Stuart Rugg

The purpose of this study was to compare abdominal muscle activity while performing a crunch on a stability ball with a traditional crunch. Forty-one healthy adults (23 men and 18 women) participated in the study. The subjects performed the crunch with the ball in 2 positions, 1 with the ball at the level of the inferior angles of the scapula (SB-high) and 1 with the ball at the level of the lower lumbar region of the back (SB-low). Surface electromyography was recorded from the upper and lower portions of the rectus abdominis and the external oblique during each repetition. Electromyography …

Challenging Perceptions Of Ability: The Women’S Challenge Stage Race, Shelley Lucas

Shelley Lucas

An Idaho institution for nearly 20 years, the Women’s Challenge bicycle race grew in size and stature despite the impact of cycling’s international governing body, whose regulations materially limited female cyclists’ physical potential.

The Summit Series: Iconic Cornucopia Of Canadian Cultural Values, Don Morrow

Donald Morrow

No abstract provided.

Ontogenetic Change In Novel Functions: Waterfall Climbing In Adult Hawaiian Gobiid Fishes, R Blob, K Wright, M Becker, T Maie, T Iverson, M Julius, H Schoenfuss

Megan Sheffield

Juveniles from three species of Hawaiian gobiid fishes climb waterfalls as part of an amphidromous life cycle, allowing them to re-penetrate adult upstream habitats after being swept out to the ocean upon hatching. The importance of climbing for juvenile stream gobies is well established, but adult fish in upstream island habitats also face potential downstream displacement by periodic disturbances. Thus, retention of climbing ability could be advantageous for adult stream gobies. Climbing performance might be expected to decline among adults, however, due to the tendency for mass-specific muscular power production to decrease with body size, and a lack of positively …

Self-Reported Psychological States And Physiological Responses To Different Types Of Motivational General Imagery, Jennifer Cumming, Tom Olphin, Michelle Law

Jennifer Cumming

The aim of the present study was to examine self-reported psychological states and physiological responses (heart rate) experienced during different motivational general imagery scenarios. Forty competitive athletes wore a standard heart rate monitor and imaged five scripts (mastery, coping, anxiety, psyching up, and relaxation). Following each script, they reported their state anxiety and self-confidence. A significant increase in heart rate from baseline to imagery was found for the anxiety, psyching-up, and coping imagery scripts. Furthermore, the intensity of cognitive and somatic anxiety was greater and perceived as being more debilitative following the anxiety imagery script. The findings support Lang’s (1977, …

A Comparison Of Once Versus Twice Per Week Training On Leg Press Strength In Women, J. Burt, R. Wilson, Jeffrey Willardson

Jeffrey Willardson

The purpose of this study was to compare strength differences between 2 groups of untrained women, who performed a single set of the leg press exercise once or twice per week. Methods. Twenty-one women were divided randomly into 2 groups: Group 1 (n=10) performed a single set of the leg press exercise once per week, while Group 2 (n=11) performed a single set of the leg press exercise twice per week for a period of 8 weeks. Throughout the duration of the study, an amount of resistance was utilized that allowed for a single set of 6 to 10 repetitions …

Exercise-Mediated Regulation Of Hsp70 Gene Expression Following Exercise Training, C.W. Melling, David Thorp, Kevin Milne, Matthew Krause, Earl Noble

Jamie Melling

An issue central to understanding the biological benefits associated with regular exercise training is to elucidate the intracellular mechanisms governing exercise-conferred cardioprotection. Heat shock proteins (HSPs), most notably the inducible 70-kDa HSP family member Hsp70, are believed to participate in the protection of the myocardium during cardiovascular stress. Following acute exercise, activation of PKA mediates the suppression of an intermediary protein kinase, ERK1/2, which phosphorylates and suppresses the activation of the heat shock transcription factor 1 (HSF1). However, following exercise training, ERK1/2 has been reported to regulate the transcriptional activation of several genes involved in cell growth and proliferation and …

Canadian Sport In Historical Perspective, Donald Morrow

Donald Morrow

No abstract provided.

Planning To Reach For An Object Changes How The Reacher Perceives It., Peter Vishton, N J. Stephens, L A. Nelson, S E. Morra, Kaitlyn L. Brunick, Jennifer A. Stevens

Peter Vishton