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Articles 1 - 6 of 6

Full-Text Articles in Life Sciences

Flax: Food And Fiber, Madeleine K. Charney Oct 2014

Flax: Food And Fiber, Madeleine K. Charney

Madeleine K. Charney

Highlights the versatile and nutritious flax plant, now cultivated worldwide.


Merci Beaucoup, Mercy Barracuda, Charles Smith, Virginia Midyette Jun 2014

Merci Beaucoup, Mercy Barracuda, Charles Smith, Virginia Midyette

Charles Kay Smith

A children's book of 45 pp for ages 9-12. The story is about a friendly Barracuda named Mercy who teaches environmentalism to schools of fish, and three children who fall in love with her.


Youth Participation In Changing Food Systems: Toward Food Justice Youth Development, Krista Harper, Catherine Sands, Diego Angarita, Molly Totman Mar 2014

Youth Participation In Changing Food Systems: Toward Food Justice Youth Development, Krista Harper, Catherine Sands, Diego Angarita, Molly Totman

Krista M. Harper

We present results from a youth participatory action research (YPAR) project in which young people from Holyoke studied the school food system in order to make positive interventions in their school district. We used the Photovoice research method, placing cameras in the hands of youth so that they themselves could document and discuss their concerns and perspectives (Wang, et al., 1996). The research was designed to gain insight about the students’ knowledge of food, nutrition, and community food systems. The research also illuminated students’ impressions of public policy, active citizenship, and community building that have arisen out of food justice …


Impact Of Accelerometer Data Processing Decisions On The Sample Size, Wear Time And Physical Activity Level Of A Large Cohort Study, Sarah Kozey Keadle, Eric Shiroma, Patty Freedson, I-Min Lee Jan 2014

Impact Of Accelerometer Data Processing Decisions On The Sample Size, Wear Time And Physical Activity Level Of A Large Cohort Study, Sarah Kozey Keadle, Eric Shiroma, Patty Freedson, I-Min Lee

Patty S. Freedson

Background Accelerometers objectively assess physical activity (PA) and are currently used in several large-scale epidemiological studies, but there is no consensus for processing the data. This study compared the impact of wear-time assessment methods and using either vertical (V)-axis or vector magnitude (VM) cut-points on accelerometer output. Methods Participants (7,650 women, mean age 71.4 y) were mailed an accelerometer (ActiGraph GT3X+), instructed to wear it for 7 days, record dates and times the monitor was worn on a log, and return the monitor and log via mail. Data were processed using three wear-time methods (logs, Troiano or Choi algorithms) and …


Systematic Screen Of Chemotherapeutics In Drosophila Stem Cell Tumors, Michele Markstein, Samantha Detorree, Julio Cho, Ralph Neumüller, Soren Craig-Müller, Norbert Perrimon Jan 2014

Systematic Screen Of Chemotherapeutics In Drosophila Stem Cell Tumors, Michele Markstein, Samantha Detorree, Julio Cho, Ralph Neumüller, Soren Craig-Müller, Norbert Perrimon

Michele Markstein

Here we report the development of an in vivo system to study the interaction of stem cells with drugs using a tumor model in the adult Drosophila intestine. Strikingly, we find that some Food and Drug Administration-approved chemotherapeutics that can inhibit the growth of Drosophila tumor stem cells can paradoxically promote the hyperproliferation of their wild-type counterparts. These results reveal an unanticipated side effect on stem cells that may contribute to tumor recurrence. We propose that the same side effect may occur in humans based on our finding that it is driven in Drosophila by the evolutionarily conserved Janus kinase-signal …


Gene Expression Profiling Identifies The Zinc-Finger Protein Charlatan As A Regulator Of Intestinal Stem Cells In Drosophila, Alla Amcheslavsky, Yingchao Nie, Qi Li, Feng He, Michele Markstein, Yt Ip, Leo Tsuda Jan 2014

Gene Expression Profiling Identifies The Zinc-Finger Protein Charlatan As A Regulator Of Intestinal Stem Cells In Drosophila, Alla Amcheslavsky, Yingchao Nie, Qi Li, Feng He, Michele Markstein, Yt Ip, Leo Tsuda

Michele Markstein

Intestinal stem cells (ISCs) in the adult Drosophila midgut can respond to tissue damage and support repair. We used genetic manipulation to increase the number of ISC-like cells in the adult midgut and performed gene expression profiling to identify potential ISC regulators. A detailed analysis of one of these potential regulators, the zinc-finger protein Charlatan, was carried out. MARCM clonal analysis and RNAi in precursor cells showed that loss of Chn function caused severe ISC division defects, including loss of EdU incorporation, phosphorylated histone 3 staining and expression of the mitotic protein Cdc2. Loss of Charlatan also led to a …