Open Access. Powered by Scholars. Published by Universities.®
- Discipline
Articles 1 - 2 of 2
Full-Text Articles in Life Sciences
Cellular Mechanism Of Thymidine Kinase 1 Secretion, Wei Meng, Kim O'Neill
Cellular Mechanism Of Thymidine Kinase 1 Secretion, Wei Meng, Kim O'Neill
Journal of Undergraduate Research
Cancer remains the second most common cause of death in the US, accounting for nearly 1 of every 4 deaths. Studies have shown that the early detection of cancer leads to better patient prognosis and a greater five-year survival rate. [1] Diagnostic and prognostic markers play a key role in classifying tumors and determining the best treatment plan for a patient. Among these biomarkers, Thymidine kinase 1 (TK1) has been studied extensively, primarily as a diagnostic biomarker for a variety of cancer types. TK1 plays a role in regulating the intracellular thymidine pools throughout the cell cycle, and thus regulates …
Do Certain Biomarkers Accurately Reflect Articular Cartilage Change Due To Physical Activity?, Alyssia Evans, Matthew Seeley
Do Certain Biomarkers Accurately Reflect Articular Cartilage Change Due To Physical Activity?, Alyssia Evans, Matthew Seeley
Journal of Undergraduate Research
Knee injury and pathology are common problems for Americans who are physically active; they affect half of all Americans who are over the age of 65, and the related annual costs are nearly twenty billion dollars. Knee pain alters running and walking neuromechanics1, and may be deleterious to knee articular cartilage. Researchers have hypothesized that if abnormal gait mechanics, due to knee pain persist, the resulting mechanical and physiological circumstances could influence genesis and progression rate of chronic knee joint pathologies, including knee osteoarthritis.