Open Access. Powered by Scholars. Published by Universities.®
Articles 1 - 6 of 6
Full-Text Articles in Life Sciences
Treating Anemia Of Chronic Disease, Sarit Fischer
Treating Anemia Of Chronic Disease, Sarit Fischer
The Science Journal of the Lander College of Arts and Sciences
Anemia of chronic disease (ACD) is the result of altered iron metabolism, blunted erythropoiesis, and shortened red blood cell survival caused by inflammatory cytokines. Hepcidin plays a key role in anemia of chronic disease by inducing endocytosis of the iron exporter ferroportin. Iron is trapped in enterocytes, hepatocytes, and macrophages, and is unavailable for hemoglobin synthesis. When treating the underlying disease is not an option, or anemia is severe, ACD should be treated. While oral iron supplementation is not suitable for ACD, intravenous iron may be effective. Erythropoiesis stimulating agents are a common approach to treating ACD, but a large …
Causes And Mechanisms Of Crohn’S Disease, Chana Weis
Causes And Mechanisms Of Crohn’S Disease, Chana Weis
The Science Journal of the Lander College of Arts and Sciences
Crohn’s disease and ulcerative colitis are the two most prevalent inflammatory bowel diseases (IBDs) in Jewish and Caucasian populations, affecting as many as one in 250 individuals. Nevertheless, the underlying causes of both disorders are not yet fully understood and remain unknown. However, current evidence suggests that the exaggerated inflammatory response, more commonly referred to as IBD, is believed to arise from dysregulation of the gastrointestinal (GI) immune system in genetically predisposed individuals who are exposed to environmental triggers. Recent advances have identified multiple IBD susceptibility genes; however, only a few environmental determinants of IBD have been consistently identified. The …
Impact Of Physical Activity On Type 2 Diabetes Mellitus, Marshall Schwartz
Impact Of Physical Activity On Type 2 Diabetes Mellitus, Marshall Schwartz
The Science Journal of the Lander College of Arts and Sciences
Type 2 diabetes mellites has become an increasingly prevalent worldwide epidemic. The tremendous economic burden, coupled with the numerous secondary risks associated with the disease, have encouraged researchers to search for causes as well as treatment methods. This research paper focuses on the effect of physical activity as a preventative measure for those at risk for diabetes and as a treatment method for those already diagnosed with the disease. The articles collected included meta-analysis, randomized controlled trials, cohort studies, surveys, etc. The studies that were analyzed have indicated an inverse relationship between physical activity and type 2 diabetes. Since there …
Are Health Problems In Adulthood Linked To Our Experiences In The Womb? An Epigenetic Approach, Simone Tendler
Are Health Problems In Adulthood Linked To Our Experiences In The Womb? An Epigenetic Approach, Simone Tendler
The Science Journal of the Lander College of Arts and Sciences
The origins of adult disease have been a prime topic for research, as deciphering causes can lead to strategies for preventions and cures. There has been recent intrigue focused on the environment in the womb. Records from England and Wales in 1911 show that those who suffered from cardiovascular disease were geographically correlated with regions high in infant mortality in the past, seventy years before the study. When looking into the cause of the neonatal death rates, low birth weight, poor maternal health, and high maternal death rates during childbirth were clearly associated. Barker inferred that there is much happening …
Is A Whole Food, Plant-Based Diet The Most Effective Treatment Of Arthritis?, Elisheva Liberman
Is A Whole Food, Plant-Based Diet The Most Effective Treatment Of Arthritis?, Elisheva Liberman
The Science Journal of the Lander College of Arts and Sciences
Arthritis is a debilitating disease where joint inflammation occurs. There are different types of arthritis, such as Osteoarthritis and Rheumatoid Arthritis. Osteoarthritis is the destruction of the articular cartilage that usually comes with age, whereas Rheumatoid Arthritis is a chronic autoimmune disease. They both have symptoms which include reduced range of motion, pain and swelling. There are various treatments to alleviate the pain and reduce the inflammation of arthritis. Among them are medication, physical therapy, surgery and a whole food, plant-based diet. The whole food, plant-based diet yields the best results and is the most effective and practical.
The Role Of Diet In Inflammatory Bowel Diseases, Aviva Smilow
The Role Of Diet In Inflammatory Bowel Diseases, Aviva Smilow
The Science Journal of the Lander College of Arts and Sciences
Inflammatory Bowel Disease encompasses two diseases, Crohn’s Disease and Ulcerative Colitis. During the last 70 years the evolving of diet in the industrialized countries has led to the utilization of foods that have been processed rather than those in their more natural original state. This increase in the processing of foods has been correlated with the more recent occurrence of metabolic diseases such as Inflammatory Bowel Disease. Patients suffering from this problem exhibit lesser amounts of anti-inflammatory bacteria such as Roseburia and Faecalibacterium and increased amounts of pro-inflammatory bacteria Escheria and Fusobacterium. Since diet directly alters the composition of the …