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Full-Text Articles in Life Sciences

Do Humans Possess The Capability To Regenerate?, Chasha Wuensch Jan 2019

Do Humans Possess The Capability To Regenerate?, Chasha Wuensch

The Science Journal of the Lander College of Arts and Sciences

Urodele amphibians, including newts and salamanders, are amongst the most commonly studied research models for regeneration. The ability to regenerate, however, is not limited to amphibians, and the regenerative process has been observed in mammals as well. This paper discusses methods by which amphibians and mammals regenerate to lend insights into human regenerative mechanisms and regenerative potential. A focus is placed on the urodele and murine digit tip models, both of which share critical regenerative stages including wound healing, histolysis, and blastema formation. Formation of the blastema proved to be a crucial process necessary for regeneration, and is responsible for …


Capsacin And Analgesia, Mimi Kornwasser Jan 2019

Capsacin And Analgesia, Mimi Kornwasser

The Science Journal of the Lander College of Arts and Sciences

Capsaicin is the active compound responsible for the pungency of hot chilli. Research has discovered its ability to desensitize peripheral nociceptive fibers which is useful in treating chronic pain disorders, specifically neuropathic pain syndromes. Capsaicin treatment comes in a variety of mediums including patches and creams and has been clinically proven to bring relief to patients with disorders such as post herpetic neuralgia, chronic regional pain syndrome and HIV related neuralgia. Exciting new forms of treatment are also in development and promise breakthroughs in the near future in this relatively young field of capsaicin-based analgesia.


Dentistry: Are Stem Cells The Future?, Tova Zemel Jan 2019

Dentistry: Are Stem Cells The Future?, Tova Zemel

The Science Journal of the Lander College of Arts and Sciences

Stem cell research is currently advancing in every area of medicine. New information about regenerating stem cells is being uncovered on a daily basis. An area of stem cells that has not been focused on until recently is the use of dental stem cells. The objective of this paper is to elucidate the most current research about dental stem cells. Much of what is discussed in this paper has not been implemented yet, and is still in clinical trials. Dental stem cells are important because they could be an alternative way of treating caries, performing root canals, and other traumas …


Car T-Cell Therapy For Acute Lymphoblastic Leukemia, Esther Langner Jan 2019

Car T-Cell Therapy For Acute Lymphoblastic Leukemia, Esther Langner

The Science Journal of the Lander College of Arts and Sciences

Despite all the available therapies, Acute Lymphoblastic Leukemia (ALL) remains extremely difficult to eradicate. Current available therapies, which include chemotherapy, radiation, and stem cell transplants, tend to be more successful in treating children than adults. While adults are more likely than children to relapse after treatment, the most common cause of treatment failure in children is also relapse. Improved outcomes for all ALL patients may depend upon new immunotherapies, specifically CAR T-cell therapy. CAR T-cell therapy extracts a patient’s own T-cells and modifies them with a CD19 antigen. This modification allows the new T-cells to recognize and kill cancer cells …


The Effects Of Rf-Emf On The Child Brain, Aaron Skaist Jan 2019

The Effects Of Rf-Emf On The Child Brain, Aaron Skaist

The Science Journal of the Lander College of Arts and Sciences

It has long been debated whether or not cell phones have a deleterious effect on the brain. Recent studies indicate that the electro-magnetic field emitted by cell phones called RF-EMF is linked to cancer. Guidelines created to limit the exposure have not been changed since 1981 and do not consider children. The mechanism thought to cause cancer is reactive oxygen species (ROS), which cause the creation of micronuclei. RF-EMF poses a greater threat to children than adults. This is due to the major anatomical differences between the head of a child and an adult. The skull of a child is …


Does In-Vitro Fertilization Increase The Risk For Birth Defects?, Tehila Tropper Jan 2019

Does In-Vitro Fertilization Increase The Risk For Birth Defects?, Tehila Tropper

The Science Journal of the Lander College of Arts and Sciences

Since 1978 when the first “petri dish” baby was born, In-Vitro Fertilization (IVF) has been used as a tool to give couples struggling with infertility the opportunity to have children. Using this method of Assisted Reproductive Technology (ART), the woman is given medication to stimulate her ovaries for the maturation of multiple eggs, which are then retrieved via needle aspiration, fertilized in a petri dish, and inserted in the uterus with the hopes of achieving a successful pregnancy. Many times IVF is completed with another technique known as Intracytoplasmic Sperm Injection (ICSI), where the sperm is injected straight into the …


Triggers Of Spermatogenesis, Moses Bibi Jan 2019

Triggers Of Spermatogenesis, Moses Bibi

The Science Journal of the Lander College of Arts and Sciences

Of the 7% of men affected with infertility, about 54% suffer from pre-testicular and/or testicular factor induced azoospermia/ oligospermia. This agenesis of spermatozoa has been the subject of much andrology research over the past 50 years, with a particular focus in the triggers of spermatogenesis. While much of their work is limited to murine populations, researchers have put a lot of emphasis on the spermatogonial stem cell (SSC) niche as the source of the trigger(s). By following physiological patterns exhibited in the seminiferous epithelium, researchers have been able to detect distinct morphological stages that correlate with spermatogonial germ-line action. Different …


Degeneration Of Rods And Cones In Retinitis Pigmentosa, Rachel Stern Jan 2019

Degeneration Of Rods And Cones In Retinitis Pigmentosa, Rachel Stern

The Science Journal of the Lander College of Arts and Sciences

Retinitis Pigmentosa, most commonly characterized by night blindness and loss of peripheral vision, is a rare genetically inherited group of diseases affecting the retina of the eye. It is estimated that 1 in 4000 people in the USA are affected by some form of the disease. Retinitis Pigmentosa (RP), is caused by a mutation or change in one or more of 55 genes. There are many causes to this disease as RP presents with many different symptoms and biological effects on the eye. These are then grouped together because they share a common result, deterioration of vision. Presently, there is …


Should Subclinical Hypothyroidism Be Treated?, Rachel Kaufman Jan 2019

Should Subclinical Hypothyroidism Be Treated?, Rachel Kaufman

The Science Journal of the Lander College of Arts and Sciences

Subclinical Hypothyroidism, SCH, has been detected with increasing frequency in recent years and has brought about major controversies regarding management and treatment [Meier et al., 2001]. The condition is characterized as having a high concentration of thyroid stimulating hormone, yet normal thyroid hormone levels and is often asymptomatic. Scientific articles retrieved from various databases helped determine some of the long term risk factors associated with SCH, including progression to overt hypothyroidism, fatty liver disease, cardiovascular disease, neuropsychiatric complications and reproductive malfunctions. Studies determining the clinical and metabolic effects of L-thyroxine hormone replacement therapy on symptoms and potential risks of SCH …


Energy Drinks: Cardiovascular Effects And The Specific Components Responsible, Malka B. Gelbfish Jan 2019

Energy Drinks: Cardiovascular Effects And The Specific Components Responsible, Malka B. Gelbfish

The Science Journal of the Lander College of Arts and Sciences

Energy drink usage as a stimulant is on the rise among adolescents and young adults. While these drinks have positive energizing effects, they pose significant health concerns. This paper examines the adverse cardiovascular effects of energy drinks and the components that could possibly be responsible. Analysis was conducted by reviewing and comparing many studies available in this area of research. Studies of energy drinks in general and energy drinks versus drinks containing caffeine alone were analyzed. Additionally, this review investigated studies of the specific ingredients in energy drinks such as caffeine, taurine, guarana, and sugar. This review found that energy …


Are There Any Viable Treatments For Age Related Macular Degeneration?, Michael Radparvar Jan 2019

Are There Any Viable Treatments For Age Related Macular Degeneration?, Michael Radparvar

The Science Journal of the Lander College of Arts and Sciences

Stem cells seem to offer an alternative venue for treating many cell related diseases, such as age-related macular degeneration (ARMD). ARMD is a progressive neurodegenerative medical condition, which primarily affects the retinal pigmented epithelium (RPE), resulting in degeneration of photoreceptors. Scientists have been successful in implanting stem cells into the eyes of rats. These injected cells sustained visual function and photoreceptor integrity without any cancerous cell formation. There are numerous treatments available to slow down the progression of ARMD. Depending on the type of ARMD, doctors may either recommend leading a healthier lifestyle or that one should undergo surgery. Numerous …


The Effects Of Aging On Skeletal Muscle Atp Production, Chaya Abboudi Jan 2019

The Effects Of Aging On Skeletal Muscle Atp Production, Chaya Abboudi

The Science Journal of the Lander College of Arts and Sciences

The study of the aging process and its prevention is an incredibly popular field; the natural course of the human body is to age and theories abound on how to avoid it. Age affects every system and pathway of the body and alters many of the bodily functions. This paper, using articles from Touro’s library database examines the different areas in which aging negatively affects ATP production. The multifaceted process associated with the production of ATP in the human body was analyzed. Several features such as the mitochondria, physical activity, and hormones are linked to ATP production and the relationship …


Impact Of Physical Activity On Type 2 Diabetes Mellitus, Marshall Schwartz Jan 2019

Impact Of Physical Activity On Type 2 Diabetes Mellitus, Marshall Schwartz

The Science Journal of the Lander College of Arts and Sciences

Type 2 diabetes mellites has become an increasingly prevalent worldwide epidemic. The tremendous economic burden, coupled with the numerous secondary risks associated with the disease, have encouraged researchers to search for causes as well as treatment methods. This research paper focuses on the effect of physical activity as a preventative measure for those at risk for diabetes and as a treatment method for those already diagnosed with the disease. The articles collected included meta-analysis, randomized controlled trials, cohort studies, surveys, etc. The studies that were analyzed have indicated an inverse relationship between physical activity and type 2 diabetes. Since there …


Are Health Problems In Adulthood Linked To Our Experiences In The Womb? An Epigenetic Approach, Simone Tendler Jan 2019

Are Health Problems In Adulthood Linked To Our Experiences In The Womb? An Epigenetic Approach, Simone Tendler

The Science Journal of the Lander College of Arts and Sciences

The origins of adult disease have been a prime topic for research, as deciphering causes can lead to strategies for preventions and cures. There has been recent intrigue focused on the environment in the womb. Records from England and Wales in 1911 show that those who suffered from cardiovascular disease were geographically correlated with regions high in infant mortality in the past, seventy years before the study. When looking into the cause of the neonatal death rates, low birth weight, poor maternal health, and high maternal death rates during childbirth were clearly associated. Barker inferred that there is much happening …


Endorphins, Endocannabinoids And Runners’ High, Elisheva Winiarz Jan 2019

Endorphins, Endocannabinoids And Runners’ High, Elisheva Winiarz

The Science Journal of the Lander College of Arts and Sciences

Modern science takes at face value the fact that exercise is beneficial for man’s health. In recent years, medical health professionals have begun to harness exercise as a treatment for a broader range of maladies. Since various studies found increased exercise to correlate with higher levels of endorphins, most believed that the endorphins were directly responsible for what the vernacular dubbed “Runner’s High.” Scientists have sought to either augment or wholly disprove the endorphin hypothesis with further studies. Major Depressive Disorder, or MDD, is an affective condition affecting a significant portion of the general population. Aerobic exercise is increasingly being …


Is A Whole Food, Plant-Based Diet The Most Effective Treatment Of Arthritis?, Elisheva Liberman Jan 2019

Is A Whole Food, Plant-Based Diet The Most Effective Treatment Of Arthritis?, Elisheva Liberman

The Science Journal of the Lander College of Arts and Sciences

Arthritis is a debilitating disease where joint inflammation occurs. There are different types of arthritis, such as Osteoarthritis and Rheumatoid Arthritis. Osteoarthritis is the destruction of the articular cartilage that usually comes with age, whereas Rheumatoid Arthritis is a chronic autoimmune disease. They both have symptoms which include reduced range of motion, pain and swelling. There are various treatments to alleviate the pain and reduce the inflammation of arthritis. Among them are medication, physical therapy, surgery and a whole food, plant-based diet. The whole food, plant-based diet yields the best results and is the most effective and practical.


The Relationship Between Pcos And Obesity: Which Comes First?, Sara L. Rosenberg Jan 2019

The Relationship Between Pcos And Obesity: Which Comes First?, Sara L. Rosenberg

The Science Journal of the Lander College of Arts and Sciences

Polycystic ovary syndrome (PCOS) is recognized as the most common reproductive disorder in women. Obesity is believed to play a central role in the development of PCOS, as many women with this condition are reported to be overweight or obese. A strong correlational relationship exists between PCOS and obesity. This paper examines the relationship between PCOS and obesity in order to determine whether PCOS causes obesity as opposed to obesity causes metabolic changes that lead to PCOS. Analysis was conducted by reviewing and comparing many studies related to the topic. Factors such as insulin resistance, hyperandrogenemia and body fat distribution …


Is There A Correlation Between Epstein - Barr Virus (Mononucleosis) And Hodgkin’S Lymphoma?, Rooth Cohen Jan 2019

Is There A Correlation Between Epstein - Barr Virus (Mononucleosis) And Hodgkin’S Lymphoma?, Rooth Cohen

The Science Journal of the Lander College of Arts and Sciences

Symptoms of acute Infectious Mononucleosis (IM), which develops after Epstein-Barr virus (EBV) in half the cases, is strikingly like those of Hodgkin’s Lymphoma (HL). This, combined with the findings that many patients with HL had a history of EBV and/or IM, triggered an interest in scientists to learn if the two were biochemically related. Many studies in this field unanimously concluded that the development of IM after EBV infection presented a higher risk of developing HL. However, whether this relationship is coincidental or pathological remains a matter of controversy until this day. In the last decade, there has been a …


The Biophysical Study Of The Efficacy Of Various Phospholipid Membranes On Daptomycin, Chaya Shor, Tamar Itzkowitz Jan 2019

The Biophysical Study Of The Efficacy Of Various Phospholipid Membranes On Daptomycin, Chaya Shor, Tamar Itzkowitz

The Science Journal of the Lander College of Arts and Sciences

Daptomycin is an important lipopeptide antibiotic used in the treatment of systematic and life-threatening infections of the skin and underlying tissue caused by Gram-positive bacteria. Calcium and phosphatidylglycerol (PG) must be present on the target cell membrane for daptomycin’s mechanism of action to proceed. Calcium and PG also promote oligomerization, a formation that has been assumed to aid in the bactericidal process. The purpose of the experiments conducted was to understand the basic biophysical properties of membrane phospholipids as they exist in their pure and mixed monolayer forms. Furthermore, the experiments conducted attempted to discern how daptomycin penetrates the different …


The Role Of Diet In Inflammatory Bowel Diseases, Aviva Smilow Jan 2019

The Role Of Diet In Inflammatory Bowel Diseases, Aviva Smilow

The Science Journal of the Lander College of Arts and Sciences

Inflammatory Bowel Disease encompasses two diseases, Crohn’s Disease and Ulcerative Colitis. During the last 70 years the evolving of diet in the industrialized countries has led to the utilization of foods that have been processed rather than those in their more natural original state. This increase in the processing of foods has been correlated with the more recent occurrence of metabolic diseases such as Inflammatory Bowel Disease. Patients suffering from this problem exhibit lesser amounts of anti-inflammatory bacteria such as Roseburia and Faecalibacterium and increased amounts of pro-inflammatory bacteria Escheria and Fusobacterium. Since diet directly alters the composition of the …


Cognitive Rigidity In Patients With Anorexia Nervosa, Miriam Sheynblyum Jan 2019

Cognitive Rigidity In Patients With Anorexia Nervosa, Miriam Sheynblyum

The Science Journal of the Lander College of Arts and Sciences

Anorexia Nervosa (AN) is a psychiatric disorder characterized by significantly low body weight and over-evaluation of weight and shape in self-identity. The complex etiology of Anorexia Nervosa renders many current treatments ineffective, thereby prolonging the course of the illness. Among the many psychological and behavioral features of AN, cognitive features like obsessiveness, rigidity, and perfectionism are often described. Patients hold firm beliefs about an ideal body weight and find it difficult to alter their thinking patterns. Recent studies have identified a pathway to understanding this disorder through characterization of it’s cognitive features. With this research, advances have been made in …


Full Issue: Volume 13, Number 1 Jan 2019

Full Issue: Volume 13, Number 1

The Science Journal of the Lander College of Arts and Sciences

Complete .pdf file of Volume 13, Number 1 of The Science Journal of the Lander College of Arts and Sciences.


Full Issue: Volume 12, Number 2 Jan 2019

Full Issue: Volume 12, Number 2

The Science Journal of the Lander College of Arts and Sciences

No abstract provided.