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Articles 1 - 20 of 20
Full-Text Articles in Life Sciences
Possible Causes Of Preeclampsia And Potential Treatments, Helene Weinreb
Possible Causes Of Preeclampsia And Potential Treatments, Helene Weinreb
The Science Journal of the Lander College of Arts and Sciences
Preeclampsia is a common complication of pregnancy characterized by hypertension and proteinuria. Its symptoms are well-defined, but the pathophysiology is not fully understood. This paper analyzes several of the most credible causes of this syndrome and attempts to relate these to the known risk factors. Current preeclampsia treatments are examined, and special focus is given to novel experimental treatments which offer hope of ending preeclampsia and eclampsia.
Full Issue: Volume 11, Number 2
Full Issue: Volume 11, Number 2
The Science Journal of the Lander College of Arts and Sciences
No abstract provided.
Pathogenic Mechanisms Of Takotsubo Cardiomyopathy Or Broken Heart Syndrome, Devorah Leah Borisute
Pathogenic Mechanisms Of Takotsubo Cardiomyopathy Or Broken Heart Syndrome, Devorah Leah Borisute
The Science Journal of the Lander College of Arts and Sciences
Takotsubo Cardiomyopathy (TTC) is a temporary heart-wall motion abnormality with the clinical presentation of a myocardial infarction. Found predominantly in postmenopausal women, TTC most often appears with apical ballooning and mid-ventricle hypokinesis. Often induced by an emotional or physical stress, TTC is reversible and excluded as a diagnosis in patients with acute plaque rupture and obstructive coronary disease. The transient nature and positive prognosis of this cardiomyopathy leaves a dilemma as to what precipitates it. This paper explores the theories of the pathogenesis of TTC including coronary artery spasm, microvascular dysfunction, and catecholamine excess. A thorough analysis of the pathogenesis …
Is Detection Of Preclinical Alzheimer’S Disease Possible?, Shana Brawer
Is Detection Of Preclinical Alzheimer’S Disease Possible?, Shana Brawer
The Science Journal of the Lander College of Arts and Sciences
No abstract provided.
The Effects Of Maternal Caffeine Intake On A Fetus, Jennifer Kahan
The Effects Of Maternal Caffeine Intake On A Fetus, Jennifer Kahan
The Science Journal of the Lander College of Arts and Sciences
The United States has been noted as the country with the greatest caffeine consumption in the world. More than half of all Americans are said to consume caffeine on a daily basis. Caffeine is easily available in a variety of dietary products including coffee, tea, soft drinks, and chocolate. Many pregnant women are unaware of the potential risk that excessive caffeine consumption can have on their unborn child. The purpose of this paper is to explore the ramifications of caffeine intake on a fetus. The studies reviewed propose that heavy maternal caffeine consumption, that of more than 300 mg daily, …
A Multi-Domain Approach To Prevention And Reversal Of Cognitive Decline, Chanah Oberlander
A Multi-Domain Approach To Prevention And Reversal Of Cognitive Decline, Chanah Oberlander
The Science Journal of the Lander College of Arts and Sciences
Incidence of dementia has been on the rise over the last few decades and it is projected that more than 130 million people will be affected by dementia worldwide by 2050. The underlying cause remains incompletely determined, and despite numerous clinical trials, no drug to date has proven effective in preventing or reversing symptoms of cognitive decline due to Alzheimer’s disease. The amyloid hypothesis as a basis for drug development of Alzheimer’s disease has thus far proven to be ineffective, suggesting that perhaps a new approach is required. New studies have shown the efficacy of a multi-domain approach which targets …
The Relationship Between Vertigo, Vestibular System Disorders, And Therapy, Etta Rubin
The Relationship Between Vertigo, Vestibular System Disorders, And Therapy, Etta Rubin
The Science Journal of the Lander College of Arts and Sciences
The relationship between vertigo and vestibular system disorders has been the subject of much research in recent years.The aim of this study is to review and analyze the relevant literature regarding this relationship, with emphasis on determining what causes the dizziness, how to test for vertigo, and specifically how to treat it.Additionally, while there may be many ways to prevent vertigo, the focus will be on how the role of therapy is vital in the future of healthcare, serving as prevention of anxiety and reoccurring vestibular disorders.
New Medical Indications For Thalidomide And Its Derivatives, Chaya Newfield
New Medical Indications For Thalidomide And Its Derivatives, Chaya Newfield
The Science Journal of the Lander College of Arts and Sciences
Thalidomide is an anti-inflammatory and an anti-angiogenesis drug that is being used around the world for a variety of malignant and inflammatory diseases. Is it justified to continue prescribing and developing thalidomide given the discovery of many well-known side effects including catastrophic birth defects? To answer this question, this paper will discuss the pharmacology and history of thalidomide, as well as many of its proposed mechanisms of action.The medical indications for the current use of thalidomide as well as for several newer and more potent derivatives are mentioned for their therapeutic results, as well as their adverse side effects.
Nonsurgical Approaches To Glioblastoma, Moshe Baitelman
Nonsurgical Approaches To Glioblastoma, Moshe Baitelman
The Science Journal of the Lander College of Arts and Sciences
Due to the sensitivity of location, brain cancer is one of the most difficult and deadly known cancers. There are various forms of cancer in the brain with many shared characteristics as well as unique manifestations in each. While cancers originating in the central nervous system present in several ways, the most common forms are high grade gliomas generally, and glioblastoma or anaplastic astrocytomas specifically. With the advent of technology, researchers have been able to propose and refine extensive profiles of these relentless tumors, enabling greater and more successful treatment profiles to be developed. Where treatments used to consist primarily …
Exercise Can Potentially Cure Parkinson’S Disease: A Comprehensive Review, Ilana Tokarsky
Exercise Can Potentially Cure Parkinson’S Disease: A Comprehensive Review, Ilana Tokarsky
The Science Journal of the Lander College of Arts and Sciences
Parkinson’s disease is the second most common neurodegenerative disease that negatively affects many American lives. It is characterized by the degeneration of dopamine-secreting neurons in the Substantia Nigra Pars Compacta (SNpc). Individuals with Parkinson’s Disease lack motor coordination and experience severe motor impairments. Unfortunately, there is currently no treatment method available that can successfully cure the disease. In fact, all of the mainstream available treatments only eliminate some PD symptoms, and they cause many negative side effects. Although nontraditional, exercise is a side effect free treatment method that can potentially slow the progression of the disease and alleviate some symptoms. …
The Association Between Type Of Fat And The Risk Of Developing Cardiovascular Diseases, Dovid Leib Glassner
The Association Between Type Of Fat And The Risk Of Developing Cardiovascular Diseases, Dovid Leib Glassner
The Science Journal of the Lander College of Arts and Sciences
Objective: To determine the significance of various types of dietary fat in the progression of atherosclerosis leading to heart disease. Methods: Study inclusion criteria constituted relevance to the discussion topic and peer reviewed literature. Age of the published material was taken into account as well, with greater preference being given to more recent research as the topic of nutrition and its relation to chronic disease remains an emerging science. Results: This research review found an overall significant relationship between the type (monounsaturated, polyunsaturated, saturated and trans-fat) of dietary fat intake and the incidence of cardiovascular disease. While earlier research identified …
By What Mechanism Does Stress Affect Ovulation?, Chana Minkowicz
By What Mechanism Does Stress Affect Ovulation?, Chana Minkowicz
The Science Journal of the Lander College of Arts and Sciences
This paper explores the many mechanisms of how stress influences ovulation. For ovulation to occur, there needs to be a series of hormones released in a specific order, and in a specific amount. This paper will discuss the various type of stress a person can experience, and which specific reproductive hormone each different type of stress disrupts. This paper will also bring proof as to how each hormone is disturbed, and by which mechanism it is disrupted. There has not been one main mechanism that has been found thus far, therefore, it is important to take into consideration the various …
What Are The Mechanisms And Effects Of Age-Related Shortening Of The Spine?, Joseph Weingarten
What Are The Mechanisms And Effects Of Age-Related Shortening Of The Spine?, Joseph Weingarten
The Science Journal of the Lander College of Arts and Sciences
Osteoporosis and Degenerative Disc Disease can cause a loss of height in the spine. This paper focuses on the mechanisms that cause age-related loss of height and its effects. Possible relationships between receptor activator nuclear factor kappa-B ligand (RANKL) and estrogen with osteoporosis are discussed, as well as possible genetic causes. Exercise may prevent osteoporosis. Osteoporosis may cause a loss of height, vertebral fracture, a decrease in maximum lung capacity, and hip fracture. Degenerative disc disease may cause shortening of the spine. Disc height loss can result in a reduction in the range of motion and stiffness at the affected …
Xenotransplantation:The Science, The Advantages, The Ethics, Chana Erlbaum
Xenotransplantation:The Science, The Advantages, The Ethics, Chana Erlbaum
The Science Journal of the Lander College of Arts and Sciences
Xenotransplantation is a breakthrough medicinal technology that is an attempt to change the lives of millions of people. The problems in the current organ transplant system risk the lives of patients each and every day. Intense waiting periods and extremely costly procedures exemplify the stress and pressure that these patients face as an attempt to save their own lives. Xenotransplantation is the idea of growing human organs in a different species, using incredible stem-cell and CRISPR technology. This can introduce an answer to some of the issues in the current transplant system. Many technical and ethical issues are becoming relevant …
Neuraxial Analgesia And Its Effects On Neonatal And Maternal Outcomes, Tziporah L. Falkowvsky
Neuraxial Analgesia And Its Effects On Neonatal And Maternal Outcomes, Tziporah L. Falkowvsky
The Science Journal of the Lander College of Arts and Sciences
Neuraxial analgesia is one of the most popular and effective forms of pain relief for labor and childbirth used by more than 50% of women in North America. Despite the standard use of the procedure, there is much that is still inconclusive about the side effects on mother and baby. Current studies show it has an impact on some outcomes and seemingly no effect on others. While the extent of the impact is still unclear, there are some adverse side effects of neuraxial analgesia, which include instrumental deliveries, respiratory distress and lower Apgar scores. Further research is required to conclude …
Full Issue: Volume 12, Number 1
Full Issue: Volume 12, Number 1
The Science Journal of the Lander College of Arts and Sciences
No abstract provided.
Relaxin As A Cure For Fibrosis, Sarah Akilov
Relaxin As A Cure For Fibrosis, Sarah Akilov
The Science Journal of the Lander College of Arts and Sciences
Until recently, relaxin has been known as a hormone that pertained to the female reproductive system. Its ability to remodel the extracellular matrix is responsible for its known reproductive effects. Current research has indicated that it may be useful as a drug to combat fibrosis. Relaxin has been proposed as an antifibrotic drug to target a variety of organs, including the skin, lung, kidney, liver, and heart. Studies done using the relaxin null knockout mouse have given scientists insight into the workings of this hormone. Human studies have also been done to test the efficacy of relaxin in its reversal …
Can Somatic Cell Nuclear Transfer Produce Human Pluripotent Stem Cells For Regenerative Medicine?, Alexandra Iskhakov
Can Somatic Cell Nuclear Transfer Produce Human Pluripotent Stem Cells For Regenerative Medicine?, Alexandra Iskhakov
The Science Journal of the Lander College of Arts and Sciences
In the last half a century, researchers and scientists discovered the application of somatic cell nuclear transfer (SCNT) to clone mammalian embryos to produce a line of pluripotent stem cells for medical and laboratory use. This is a breakthrough technology that is applied to stem cell research, regenerative medicine, and cloning. Somatic cells are non-germ cells that are differentiated but provide the nuclei that are transferred to enucleated oocytes. The replacement of the nuclei results in a developing embryo that contains the genetic information of the donated nucleus, which can either be transplanted into a surrogate mother to produce a …
Uvb Induced Mutation Of P53 In Non Melanoma Skin Cancer, Raizy Berger
Uvb Induced Mutation Of P53 In Non Melanoma Skin Cancer, Raizy Berger
The Science Journal of the Lander College of Arts and Sciences
There is a clear correlation between excessive sun exposure and the development of skin cancer. UVB radiation from the sun is potent, and as the ozone layer gets depleted, more UVB can reach Earth and cause cell damage. UV radiation causes DNA lesions, such as 6-4 photoproducts and cyclobutane pyrimidine dimers. Cyclobutane pyrimidine dimers are more abundant and take longer to be repaired and therefore are responsible for most of the mutation and DNA damage. These DNA lesions lead to mutation of the p53 gene. The signature mutation on p53 from UV radiation is a CC to TT mutation, which …
Music And The Brain, Maddie Nierman
Music And The Brain, Maddie Nierman
The Science Journal of the Lander College of Arts and Sciences
Music is an important part of cultures worldwide. It has been used throughout the ages as a method of conveying emotions to the listener. However, there is some confusion about exactly which areas of the brain are affected by music. This study shows the general areas of the brain stimulated by music, explaining how these sections influence emotion and learning capability. In addition, this paper demonstrates that music therapy may be helpful in relieving stress or some neurological disorders, based on the areas activated by music. Training in music has cognitive and motor coordination benefits, as well, because this training …