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Full-Text Articles in Life Sciences

Palmitoylation As A Regulator Of Maguk Proteins Postsynaptic Localization, Rozena Shirvani-Arani, Santiago Balderas, Yonghong Zhang, Xioaqian Fang Sep 2023

Palmitoylation As A Regulator Of Maguk Proteins Postsynaptic Localization, Rozena Shirvani-Arani, Santiago Balderas, Yonghong Zhang, Xioaqian Fang

Research Symposium

Synaptic plasticity is the ability of the brain to make changes and the changes occur at synapses. To achieve the complicated functions, a good number of proteins are present at synapse and are called synaptic proteins. To stabilize these proteins at synapses, proteins are modified through posttranslational modifications (PTMs). The most studied PTMs include phosphorylation, acetylation, ubiquitination, glycosylation, palmitoylation, etc. Palmitoylation is a type of lipid modification and has received more attention recently for its contribution to protein trafficking, localization, and interaction in various synaptic plasticity. The membrane-associated guanylate kinase (MAGUK) family includes PSD-95, PSD-93 (also known as chapsyn-110), SAP102, …


The Mandelbrot Set For Networks, Templates And Mutated Systems, Anca R. Radulescu May 2023

The Mandelbrot Set For Networks, Templates And Mutated Systems, Anca R. Radulescu

Biology and Medicine Through Mathematics Conference

No abstract provided.


Intermittent Synchronization In Gamma-Band Neural Oscillations, Anh Nguyen, Leonid L. Rubchinsky May 2023

Intermittent Synchronization In Gamma-Band Neural Oscillations, Anh Nguyen, Leonid L. Rubchinsky

Biology and Medicine Through Mathematics Conference

No abstract provided.


Investigation Of Neurotransmitter’S Knockdown Effect On Drosophila Melanogaster Female Aggression, Asil N. El Galad Aug 2022

Investigation Of Neurotransmitter’S Knockdown Effect On Drosophila Melanogaster Female Aggression, Asil N. El Galad

Undergraduate Student Research Internships Conference

Drosophila melanogaster (D. melanogaster) is a popular model organism in neurobiology. While aggression has been studied heavily in male drosophila, there's minimal research on aggression in female drosophila. Neurotransmitters influencing aggressive behaviour in female D. melanogaster are poorly understood. Various neurotransmitters such as dopamine, octopamine, and serotonin influence aggression in D. melanogaster Further investigation of the role of neurotransmitters on aggression is thus important. The purpose of our experiment is to observe the effect of the knockdown of dopamine, octopamine and glutamate on aggression in female D. melanogaster.


Resistance Training Improves White Matter Structural Connectivity In Older Adults At-Risk For Cognitive Decline, Ryu Lien Aug 2022

Resistance Training Improves White Matter Structural Connectivity In Older Adults At-Risk For Cognitive Decline, Ryu Lien

Undergraduate Student Research Internships Conference

Diabetes is a global health concern that impacts 415 million people worldwide. Individuals who are at-risk for diabetes (characterized by high blood glucose and/or being overweight) have white matter atrophy, decreased cognitive function, and an increased risk of Alzheimer’s disease (AD). Recently, resistance training (RT) has been shown to lower white matter atrophy and white matter lesion volume. However, investigating changes in white matter tracts is complex, hence previous findings remain inconclusive. Diffusion tensor imaging (DTI) serves as a highly sensitive tool that enables visualization and characterization of white matter tracts and has the potential to combat this complexity. The …


Mixed Mode Oscillations In Three-Timescale Coupled Morris-Lecar Neurons, Ngocanh Phan, Yangyang Wang May 2022

Mixed Mode Oscillations In Three-Timescale Coupled Morris-Lecar Neurons, Ngocanh Phan, Yangyang Wang

Biology and Medicine Through Mathematics Conference

No abstract provided.


Mathematical Model Of Subthalamic Nucleus Neuron - Characteristic Activity Patterns And Bifurcation Analysis, Choongseok Park, Sungwoo Ahn, Leonid Rubchinsky May 2022

Mathematical Model Of Subthalamic Nucleus Neuron - Characteristic Activity Patterns And Bifurcation Analysis, Choongseok Park, Sungwoo Ahn, Leonid Rubchinsky

Biology and Medicine Through Mathematics Conference

No abstract provided.


Automated Fitting Of Allosteric Parameters In Receptor Oligomer Models, Spenser Wood May 2022

Automated Fitting Of Allosteric Parameters In Receptor Oligomer Models, Spenser Wood

Biology and Medicine Through Mathematics Conference

No abstract provided.


Estimating Glutamate Transporter Surface Density In Mouse Hippocampal Astrocytes, Anca R. Radulescu, Annalisa Scimemi May 2022

Estimating Glutamate Transporter Surface Density In Mouse Hippocampal Astrocytes, Anca R. Radulescu, Annalisa Scimemi

Biology and Medicine Through Mathematics Conference

No abstract provided.


Computational Model Of Mutant Arpp Protein Aggregation And Diffusion And Its Impact On Calcium Dynamics And Stress Responses Using Neuron., Gaby Clarke May 2022

Computational Model Of Mutant Arpp Protein Aggregation And Diffusion And Its Impact On Calcium Dynamics And Stress Responses Using Neuron., Gaby Clarke

Biology and Medicine Through Mathematics Conference

No abstract provided.


Scale-Free Properties Influence Breathing Rhythmogenesis., Cameron Grover May 2022

Scale-Free Properties Influence Breathing Rhythmogenesis., Cameron Grover

Biology and Medicine Through Mathematics Conference

No abstract provided.


Olfactory Bulb Processing Of Ortho Versus Retronasal Odors, Michelle F. Craft, Andrea Barreiro, Shree Gautam, Woodrow Shew, Cheng Ly May 2022

Olfactory Bulb Processing Of Ortho Versus Retronasal Odors, Michelle F. Craft, Andrea Barreiro, Shree Gautam, Woodrow Shew, Cheng Ly

Biology and Medicine Through Mathematics Conference

No abstract provided.


Noise As A Strategy, Nour Riman, Bard Ermentrout May 2022

Noise As A Strategy, Nour Riman, Bard Ermentrout

Biology and Medicine Through Mathematics Conference

No abstract provided.


Empirical And Computational Approaches To Explore The Underlying Neuromodulatory Mechanisms Of Social Status Regulation On Zebrafish Motor Circuits, Sungwoo Ahn, Choongseok Park, Fadi Issa May 2022

Empirical And Computational Approaches To Explore The Underlying Neuromodulatory Mechanisms Of Social Status Regulation On Zebrafish Motor Circuits, Sungwoo Ahn, Choongseok Park, Fadi Issa

Biology and Medicine Through Mathematics Conference

No abstract provided.


Probability Distributions Of Active Sensing, Kathleen Hoffman May 2022

Probability Distributions Of Active Sensing, Kathleen Hoffman

Biology and Medicine Through Mathematics Conference

No abstract provided.


Memoir Dataset: Quantifying Image Memorability In Adolescents, Gal Almog, Yalda Mohsenzadeh Aug 2021

Memoir Dataset: Quantifying Image Memorability In Adolescents, Gal Almog, Yalda Mohsenzadeh

Undergraduate Student Research Internships Conference

Every day, humans observe and interact with hundreds of images and scenes; whether it be on a cellphone, on television, or in print. Yet a vast majority of these images are forgotten, some immediately and some after variable lengths of time. Memorability is indeed a property intrinsic to all images that can be extracted, as well as predicted. While memory itself is a process that occurs in the brain of an individual, the concept of memorability is an intrinsic, continuous property of a stimulus that can be both measured and manipulated. We selected images from the MemCat data set that …


Patch Clamps, Electrophysiology, And The Optimistic Future Of Neuroscience At Usu, Riley Conover-Elmer Apr 2021

Patch Clamps, Electrophysiology, And The Optimistic Future Of Neuroscience At Usu, Riley Conover-Elmer

Student Research Symposium

The Neuroscience department is a small, yet nonetheless rapidly growing field at Utah State University. While many students are encouraged to take classes from related fields such as psychology and biology, an official Bachelor's degree has not yet been published for the university. As one of those students, digging deeper into the world of neuroscience has yielded many discoveries on biology/behavior relations that go largely unnoticed by the general student population. However, in preparation for a coming Neuroscience Major, I was given the opportunity to assist Dr. Sara Freeman in preparing for a Neurophysiology Lab course in the Spring of …


How The Amino Acid L-Serine Provides Neuroprotection Against L-Bmaa Induced Alzheimer’S Disease, Joseph Cimino Jan 2021

How The Amino Acid L-Serine Provides Neuroprotection Against L-Bmaa Induced Alzheimer’S Disease, Joseph Cimino

Capstone Showcase

More than 6 million people in America are living with Alzheimer’s Disease (AD) and there are currently no cures or treatments. It is time to move on from the ꞵ-amyloid hypothesis and broaden AD research. New research is suggesting that dietary exposure to a cyanobacterial toxin known as L-BMAA is causing neurodegenerative diseases such as AD, Amyotrophic lateral sclerosis (ALS), and Parkinson’s Disease. L-BMAA is misincorporated during protein folding, in place of the proper amino acid, L-Serine. It has been shown that the naturally occurring amino acid, L-Serine, can provide neuroprotection against L-BMAA, but the mechanism by which L-Serine infers …


Nonlinear Control Of Biological Dynamical Systems, Megan J. Morrison May 2020

Nonlinear Control Of Biological Dynamical Systems, Megan J. Morrison

Biology and Medicine Through Mathematics Conference

No abstract provided.


Oscillations Via Excitable Cells, Derek Orr, Bard Ermentrout May 2020

Oscillations Via Excitable Cells, Derek Orr, Bard Ermentrout

Biology and Medicine Through Mathematics Conference

No abstract provided.


Modeling Of Pmv Neuronal Circuitry In Adaptive Changes Of Energy Balance, Pilhwa Lee, Cristina Saenz De Miera, Nicole Bellefontaine, Kevin W. Williams, Renata Frazao, Carol Elias May 2020

Modeling Of Pmv Neuronal Circuitry In Adaptive Changes Of Energy Balance, Pilhwa Lee, Cristina Saenz De Miera, Nicole Bellefontaine, Kevin W. Williams, Renata Frazao, Carol Elias

Biology and Medicine Through Mathematics Conference

No abstract provided.


Geometry-Based Estimates Of Glutamate Transporter Density In Astrocytes, Anca R. Radulescu, Cassandra Williams, Annalisa Scimemi May 2020

Geometry-Based Estimates Of Glutamate Transporter Density In Astrocytes, Anca R. Radulescu, Cassandra Williams, Annalisa Scimemi

Biology and Medicine Through Mathematics Conference

No abstract provided.


Socially Regulated Neural Circuits Activation Via Endocannabinoid And Dopaminergic Signaling In Zebrafish, Choongseok Park May 2019

Socially Regulated Neural Circuits Activation Via Endocannabinoid And Dopaminergic Signaling In Zebrafish, Choongseok Park

Biology and Medicine Through Mathematics Conference

No abstract provided.


Bifurcation Analysis Of A Photoreceptor Interaction Model For Retinitis Pigmentosa, Anca R. Radulescu May 2019

Bifurcation Analysis Of A Photoreceptor Interaction Model For Retinitis Pigmentosa, Anca R. Radulescu

Biology and Medicine Through Mathematics Conference

No abstract provided.


Spiking Activity In Networks Of Neurons Impacted By Axonal Swelling, Brian Frost, Stan Mintchev May 2019

Spiking Activity In Networks Of Neurons Impacted By Axonal Swelling, Brian Frost, Stan Mintchev

Biology and Medicine Through Mathematics Conference

No abstract provided.


A Model Of Online Latent State Learning, Amy Cochran May 2019

A Model Of Online Latent State Learning, Amy Cochran

Biology and Medicine Through Mathematics Conference

No abstract provided.


Predicting Dynamics From Hardwiring In Canonical Low-Dimensional Coupled Networks, Anca R. Radulescu May 2019

Predicting Dynamics From Hardwiring In Canonical Low-Dimensional Coupled Networks, Anca R. Radulescu

Biology and Medicine Through Mathematics Conference

No abstract provided.


Brain Network Structure And Interventions In A Computational Model Of Epilepsy, Joe Emerson Apr 2019

Brain Network Structure And Interventions In A Computational Model Of Epilepsy, Joe Emerson

Student Symposium

Some forms of drug-resistant epilepsy can only be treated via surgical intervention. This form of treatment requires the removal of a part of the brain identified as the seizure source. Current methods for surgical treatment are risky and many times unsuccessful. A deeper understanding of how brain connectivity facilitates seizure propagation is necessary for developing improved surgical techniques. Experimental limitations make certain clinical investigations of epilepsy difficult or impossible, but computational modeling offers a way forward when experimentation in living systems is impractical or unsafe. We used a full-hemisphere computational model for epilepsy to investigate the role of network structure …


Effects Of Configuration On Ensemble Dynamics In A Network Of Wilson-Cowan Nodes, Anca R. Radulescu Jun 2018

Effects Of Configuration On Ensemble Dynamics In A Network Of Wilson-Cowan Nodes, Anca R. Radulescu

Biology and Medicine Through Mathematics Conference

No abstract provided.


Neural Phase Oscillators Incorporating Noise And Correlated Sources Of Heterogeneity, Kyle Wendling Jun 2018

Neural Phase Oscillators Incorporating Noise And Correlated Sources Of Heterogeneity, Kyle Wendling

Biology and Medicine Through Mathematics Conference

No abstract provided.