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Articles 1 - 12 of 12
Full-Text Articles in Life Sciences
Family-Based Interventions Impact On Pediatric Obesity, Renee Camins
Family-Based Interventions Impact On Pediatric Obesity, Renee Camins
Nursing | Student Research Posters
Background: Obesity rates among children in the United States have been on the rise, with 19.7% of children aged 2-19 classified as obese (CDC, 2022). Low socioeconomic status is a risk factor for pediatric obesity,Children from low-income households are more likely to be overweight or obese than their peers from higher economic backgrounds. Obesity can lead to serious and chronic health problems such as diabetes, high blood pressure, and breathing difficulties, and is also a risk factor for leading causes of death in adults including stroke, cardiovascular disease, and cancer (CDC, 2022). Educational interventions and access to exercise resources may …
The Role That Diet And Lifestyle Factor Plays In An Increased Risk For Cardiovascular Disease In Asians And Pacific Islanders, Ethan Caragan
The Role That Diet And Lifestyle Factor Plays In An Increased Risk For Cardiovascular Disease In Asians And Pacific Islanders, Ethan Caragan
Nursing | Student Research Posters
Cardiovascular disease is the leading global cause of mortality, often resulting in heart attacks and strokes due to obstructed blood flow to vital organs. The risk of these events is influenced by dietary choices, smoking, and physical activity. Despite preventative measures, the impact of diet and lifestyle on cardiovascular health varies across ethnic groups. This thesis aims to evaluate how variations in dietary traditions and lifestyle among Asians and Pacific Islanders contribute to increased or decreased cardiovascular disease risks compared to other racial groups. The study focuses on the dietary and lifestyle factors of Asian Americans and Pacific Islanders in …
Effect Of Cyclooxygenase-2 Glycosylation On Downstream Expression Of E-Cadherin And Β-Catenin In Mcf-7 Breast Cancer Cells, Genna Roan, Grace Alexander, Klarisse Cruz, Janelle Nguyen, Mary B. Sevigny
Effect Of Cyclooxygenase-2 Glycosylation On Downstream Expression Of E-Cadherin And Β-Catenin In Mcf-7 Breast Cancer Cells, Genna Roan, Grace Alexander, Klarisse Cruz, Janelle Nguyen, Mary B. Sevigny
Natural Sciences and Mathematics | Faculty Research Posters
Cyclooxygenase-2 (COX-2) is an enzyme that helps catalyze the formation of prostaglandins, which promote inflammation, pain, and fever and maintain other normal physiological functions throughout the body. However, the overexpression of COX-2 has been found to play a role in various diseases including breast cancer. COX-2 exists as two major glycoforms— 72 kDa and 74 kDa— due to the glycosylation site Asn580 which is glycosylated 50% of the time. Past studies from our lab have shown that this glycosylation regulates COX-2 protein turnover in the cell3. The proteins E-cadherin— a tumor suppressor— and β-catenin— a tumor driver— can be regulated …
Stem Cell Derived Osteoprogenitors And Their Role In Bone Repair Using Morphogenic Activators, George Washington Brownridge Iii, Sylvanna Islas, Angelina Miller, Warren Hoeffler
Stem Cell Derived Osteoprogenitors And Their Role In Bone Repair Using Morphogenic Activators, George Washington Brownridge Iii, Sylvanna Islas, Angelina Miller, Warren Hoeffler
Student Research Posters
Bone constantly cycles through a dynamic process of breakdown and remodeling. Osteoblasts are the specialized mesenchymal stem cells that have a major role in bone formation and the remodeling process whereas their counterpart osteoclasts, handle bone resorption. Embryonic stem cells can be partially differentiated into Progenitor cells, and we worked with #18, a candidate for being an osteoprogenitor that has the potential to respond to morphogenic activators. In the case of bone remodeling, TGF-β 2, BMP-2 and an abundance of CA++ have been shown to be potential activators of differentiation into osteoblasts. Eight different trials were conducted with the cells …
Stress Reducing Effects Of Indoor Plants In A Classroom Setting, Laura Tennant
Stress Reducing Effects Of Indoor Plants In A Classroom Setting, Laura Tennant
Student Research Posters
Previous research has demonstrated that natural views and access to plants appear to have significant beneficial effects on individuals (Relf, 1992). Studies of green views out of a classroom window showed significant reductions in students’ mental fatigue (Li & Sullivan, 2016), and studies of indoor plants in hospital settings showed stress reduction and increased healing rates in patients (Ulrich, 1984). Indoor plants in the workplace demonstrated improved employee performance (Kweon, Ulrich, Walker, & Tassinary, 2008). However, there have been few studies examining the impact indoor plants might have in a classroom setting. This study used an experimental design to measure …
Living With Fragile X Syndrome: Occupations As An Outcome Measure In A Clinical Trial, Kaylee E. Gothelf, Ty Duong, Ana Baldinger, Theresa Chase
Living With Fragile X Syndrome: Occupations As An Outcome Measure In A Clinical Trial, Kaylee E. Gothelf, Ty Duong, Ana Baldinger, Theresa Chase
Student Research Posters
The purpose of this study was to evaluate the use of semi-structured interviews as an outcome measure in a clinical trial for children with fragile X syndrome (FXS) ages 2-6. This qualitative approach was used to analyze twenty-five interviews of parents with children in a double-blind medication trial - sertraline or placebo. The aim was to assess occupational improvements in their child that may not have been detected with the use quantitative outcome measures alone. Results showed greater improvements in the sertraline group in areas of behavior, social participation, sensory-related behaviors, receptive language, education, family impact and therapeutic strategies. Our …
Scale Up Isolation Of Aaptamine For In Vivo Evaluation Indicates Its Neurobiological Activity Is Linked To The Delta Opioid Receptor, Eptisam Lambu, Nicole L. Mcintosh, Madeline Ferwerda, Allison Coker, Laura Millan-Lobo, Nicholas Lorig-Roach, Phillip Crews, Jennifer L. Whistler
Scale Up Isolation Of Aaptamine For In Vivo Evaluation Indicates Its Neurobiological Activity Is Linked To The Delta Opioid Receptor, Eptisam Lambu, Nicole L. Mcintosh, Madeline Ferwerda, Allison Coker, Laura Millan-Lobo, Nicholas Lorig-Roach, Phillip Crews, Jennifer L. Whistler
Student Research Posters
Opioid receptors belong to the large superfamily of seven transmembrane-spanning (7TM) G protein-coupled receptors (GPCRs). As a class, GPCRs are of fundamental physiological importance mediating the actions of the majority of known neurotransmitters and hormones. The Mu (µ), Delta (δ) and Kappa (MOR, DOR, KOR) opioid receptors are particularly intriguing members of this receptor family as they are the targets involved in many neurobiological diseases such as addiction, pain, stress, anxiety, and depression. To date few marine natural products have been investigated for their neurobiological activities.1 One noteworthy example involves ziconotide (1) from the cone snail Conus magnus.2 Compound 1 …
Scale Up Isolation Of Aaptamine For In Vivo Evaluation Indicates Its Neurobiological Activity Is Linked To The Delta Opioid Receptor, Nicole L. Mcintosh, Eptisam Lambu, Laura Millan-Lobo, Fei Li, Li He, Phillip Crews, Jennifer L. Whistler, Tyler Johnson
Scale Up Isolation Of Aaptamine For In Vivo Evaluation Indicates Its Neurobiological Activity Is Linked To The Delta Opioid Receptor, Nicole L. Mcintosh, Eptisam Lambu, Laura Millan-Lobo, Fei Li, Li He, Phillip Crews, Jennifer L. Whistler, Tyler Johnson
Student Research Posters
Opioid receptors belong to the large superfamily of seven transmembrane-spanning (7TM) G protein-coupled receptors (GPCRs). As a class, GPCRs are of fundamental physiological importance mediating the actions of the majority of known neurotransmitters and hormones. The Mu, Delta, and Kappa (MOP, DOP, KOP) opioid receptors are particularly intriguing members of this receptor family as they are the targets involved in many neurobiological diseases such as addiction, pain, stress, anxiety, and depression. Recently we discovered that the aaptamine class of marine sponge derived natural products exhibit selective agonist activity in vitro for the DOP versus MOP receptor. Our findings may explain …
Glycosylation Of Cyclooxygenase-2 (Cox-2) Influences The Migratory And Invasive Potential Of Cells, Fahad Algaly, Julia Hand, Mary B. Sevigny
Glycosylation Of Cyclooxygenase-2 (Cox-2) Influences The Migratory And Invasive Potential Of Cells, Fahad Algaly, Julia Hand, Mary B. Sevigny
Natural Sciences and Mathematics | Faculty Research Posters
Prostaglandins are bioactive lipids involved in many physiological functions such as maintenance of the cardiovascular, immune, renal, and central nervous systems. They also play a role in certain diseases like arthritis, cancer, and Alzheimer’s. Cyclooxygenase-2 (COX-2) is the enzyme that catalyzes the initial rate-limiting step in the pathway that converts arachidonic acid to prostaglandins. COX-2 exists as two glycoforms with the molecular weights of 72 and 74 kDa, the latter resulting from the addition of a high mannose chain to the Asn580 residue ~50% of the time. The over-expression of COX-2 is believed to be linked to cancer progression and …
Glycosylation Of Cyclooxygenase-2 (Cox-2) Influences The Migratory Potential Of Cos-1 Cells, Julia Hand, Renee Dominguez, Miguel Regidor, Mary B. Sevigny
Glycosylation Of Cyclooxygenase-2 (Cox-2) Influences The Migratory Potential Of Cos-1 Cells, Julia Hand, Renee Dominguez, Miguel Regidor, Mary B. Sevigny
Natural Sciences and Mathematics | Faculty Research Posters
A cancer cell’s most threatening property is its ability to metastasize or detach from the primary tumor and migrate to other locations in the body. Previous studies have shown that overexpression of the enzyme cyclooxygenase-2 (COX-2) can increase the metastatic potential of several cell types. COX-2 is the rate-limiting enzyme in the prostanoid biosynthesis pathway, converting arachidonic acid to prostaglandin H2, an important signaling molecule in the body. Glycosylation of COX-2 at the amino acid site Asn580 occurs about 50% of the time, and this results in two forms of the enzyme with molecular weights 72 and 74kDa. The purpose …
Potential Role Of Micro-Algae On Global Energy Supply, Sage Callaway-Keeley, Stephanie Huynh
Potential Role Of Micro-Algae On Global Energy Supply, Sage Callaway-Keeley, Stephanie Huynh
Student Research Posters
The most effective ways to reduce CO2 emissions are to improve the energy efficiency of each economic sector and to reduce the cutting of tropical and temperate forests around the world. These options, however, may not fully reach their technical and economic potential due to various political and socioeconomic. The most practical of these is to increase CO2 sinks through photosynthesis in both standing tree biomass and in ocean primary producers. The use of marine algae as CO2 sinks is for large-scale CO2 mitigation: the use of phytoplankton through Fe fertilization and macro algal (kelp) farms, which can be used …
Biofuels: A Hands-On Approach, Learning The Potential Of Utilizing Non-Food Sources, Alexandra Ham, Gabrielle Pecora, Hoaithuong Bui, Timothy Camarella, Victor Pham, Marc Ting
Biofuels: A Hands-On Approach, Learning The Potential Of Utilizing Non-Food Sources, Alexandra Ham, Gabrielle Pecora, Hoaithuong Bui, Timothy Camarella, Victor Pham, Marc Ting
Student Research Posters
The global energy economy is huge and thoughts of replacing large amounts of petroleum based fuels by massive levels of fermentation of grains are not realistic. On an energy basis what global agriculture produces for food will almost cover the energy demands if all of it is redirected to the production of fuels—either as alcohols for gasoline or as fat derivatives for diesel fuel. This means that chemical processes need to be developed that allow inclusion of non-food based agricultural and urban wastes as well as forest debris into the energy economy. These represent opportunities to capture new sources of …