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Full-Text Articles in Life Sciences

Science, Physiology, And Nutrition For The Nonscientist, Judi S. Morrill May 2022

Science, Physiology, And Nutrition For The Nonscientist, Judi S. Morrill

Open Educational Resources

A wonderful blend of physiology, nutrition, biochemistry, genetics, biology, evolution, chemistry--what we all need to know as informed citizens. A basic knowledge of the life sciences and how our bodies work--to promote our own good health, especially as we're bombarded with misleading advertisements, soundbites, and the like. DNA fingerprinting, calorie requirements, dietary advice, genetic engineering (including gene editing with CRISPR cas9)--all in an easy-to understand book.


Biol 352 Cell Biology: Journey From The Center Of The Cell, Meredith A. Rowe Ph.D. May 2022

Biol 352 Cell Biology: Journey From The Center Of The Cell, Meredith A. Rowe Ph.D.

Open Educational Resources

This project is intended to be a long-term, scaffolded project across an entire semester course. Due dates are spread throughout the semester, and points are distributed as the professor deems appropriate across the sections of the project.


2021-2022 Program And Abstracts: Celebration Of Student Scholarship, Morehead State University. Undergraduate Research Fellowship Program. Apr 2022

2021-2022 Program And Abstracts: Celebration Of Student Scholarship, Morehead State University. Undergraduate Research Fellowship Program.

2022 Celebration of Student Scholarship - Poster Presentations

The 2021-2022 Program and Abstracts for the Celebration of Student Scholarship at Morehead State University held on April 27, 2022. A Showcase of Student Research, Scholarship, Creative Work, and Performance Arts.


Shew Family Farms Shares Their Story In Honor Of Athen's Farmers Market 50th Anniversary, Marjorie Shew, Kassidy Rock Apr 2022

Shew Family Farms Shares Their Story In Honor Of Athen's Farmers Market 50th Anniversary, Marjorie Shew, Kassidy Rock

Spring 2022 Oral Histories: Athens Farmers Market and The Ridges

Member of the Athens Farmers Market since1984, Marjie Shew of Shew Family Farms, now known as Shew's Grassfed Beef, shares her story. From beginning in upstate New York to living on a commune in West Virginia, to owning an orchard with her husband in Morgan County, Ohio and every step in between.


Flea The Flyentist: Mimicry, Oh My!, Molly Fitzgerald Apr 2022

Flea The Flyentist: Mimicry, Oh My!, Molly Fitzgerald

Open Access Books

"Flea The Flyentist: Mimicry, Oh My!" Showcases many interesting cases of arthropod mimicry. Learn about all sorts of mimics in this children's book!


Investigation Of Magnesium Cation-Proton Exchange With Transmembrane Electrostatically Localized Protons (Telp) At A Liquid-Membrane Interface: Fundamental To Bioenergetics, Gyanendra Kharel, Andrew J. Evans, Christopher M. Russo, Michael Eason, James W. Lee Apr 2022

Investigation Of Magnesium Cation-Proton Exchange With Transmembrane Electrostatically Localized Protons (Telp) At A Liquid-Membrane Interface: Fundamental To Bioenergetics, Gyanendra Kharel, Andrew J. Evans, Christopher M. Russo, Michael Eason, James W. Lee

College of Sciences Posters

The Lee transmembrane electrostatic proton localization (TELP) theory is a revolutionary scientific theory that has successfully explained decades long-standing quandary in the field of bioenergetics in regards to ATP synthesis in biological systems, specifically alkalophilic bacteria. This study provides experimental support for the TELP theory by further demonstrating evidence of a localized proton layer existing at the liquid-membrane interface in a simulated biological membrane apparatus. Whilst monovalent cations have been studied extensively, divalent cation exchange has not been studied experimentally.

A previous study determined equilibrium constant for Na+ and K+ to exchange with localized H+ layer to be (5.07 ...


A Pathway To Solving The Structure Of Cl-Par-4 Tumor Suppressor Protein: Challenges & Findings, Krishna Raut, Samjhana Pandey, Andrea M. Clark, Komala Ponniah, Steven M. Pascal Apr 2022

A Pathway To Solving The Structure Of Cl-Par-4 Tumor Suppressor Protein: Challenges & Findings, Krishna Raut, Samjhana Pandey, Andrea M. Clark, Komala Ponniah, Steven M. Pascal

College of Sciences Posters

Prostate apoptosis response-4 (Par-4) is a pro-apoptotic tumor suppressor protein. Down-regulation of this protein has been reported in a myriad of cancers. Conversely, up-regulation of Par-4 is found to be associated with several neurodegenerative disorders. Par-4 is unique in the sense it can selectively induce apoptosis in cancer cells. For this, caspase-dependent intracellular cleavage of Par-4 is essential to produce the functionally active fragment, cl-Par-4 (caspase-cleaved Par-4). The cl-Par-4 protein inhibits the NF-κB-mediated cell survival pathway and causes selective apoptosis in various tumor cells.

Our laboratory is interested in determining the structure of cl-Par-4 and understanding it’s interaction with ...


Understanding The Natural History Of Juvenile Amblyomma Maculatum In Southeastern Virginia, Christina Espada, Holly Gaff Apr 2022

Understanding The Natural History Of Juvenile Amblyomma Maculatum In Southeastern Virginia, Christina Espada, Holly Gaff

College of Sciences Posters

Amblyomma maculatum, the Gulf Coast tick, is a species of increasing public health concern. Adult A. maculatum is a known vector of several pathogens including Rickettsia parkeri, the causative agent of Rickettsia parkeri rickettsiosis. Amblyomma maculatum has expanded northward from its historic range along the Gulf Coast, with populations reportedly establishing in southeastern Virginia in 2010. Recently established populations of A. maculatum tend to have higher R. parkeri infection prevalence compared to longer established populations. This pattern holds for all populations found so far in southeastern Virginia, with a prevalence of R. parkeri in about 60% of A. maculatum compared ...


Funding Achievement In Kentucky, Brett Blair, James Masterson Apr 2022

Funding Achievement In Kentucky, Brett Blair, James Masterson

2022 Celebration of Student Scholarship - Poster Presentations

It is no surprise that the proper education of a population ranks high on the list of important accomplishments within a society. After all, a population’s education can affect its ability to perform at a high capacity. The education of Kentucky’s children is no different. Recent years have seen large disparities in the resources available to each school in Kentucky, which could have effects on the educational output of regions in the state. Though research has been conducted on concepts such as school funding, educational quality, and education reform, this research tends to be lacking in specificity and ...


A Preliminary Survey On The Biodiversity Of Wasps In Eastern Kentucky, Lorien Molstad, Zoe Baker, Julia Fitzpatrick, Bethany Lucio, Sean O'Keefe Apr 2022

A Preliminary Survey On The Biodiversity Of Wasps In Eastern Kentucky, Lorien Molstad, Zoe Baker, Julia Fitzpatrick, Bethany Lucio, Sean O'Keefe

2022 Celebration of Student Scholarship - Poster Presentations

Biodiversity is the measure of variability of interactions between living organisms within an area. Biodiversity contributes significantly to the production of different life sustaining resources and supports a diversity of ecological life. A greater biodiverse area can help maintain environmental balance and maintain ecological diversity and health. There are multiple economic, cultural, and scientific reasons as to why biodiversity is important. When assessing biodiversity, mammals and birds are commonly used as surrogates. The problem with mammals and birds is that there are relatively few species and relatively few individuals in an area, so quantitative assessment can be difficult. However, insects ...


Creating The First Genetically Engineered Eukaryote With Circular Chromosomes, Duncan Mcginnis, Melissa Mefford Apr 2022

Creating The First Genetically Engineered Eukaryote With Circular Chromosomes, Duncan Mcginnis, Melissa Mefford

2022 Celebration of Student Scholarship - Poster Presentations

Prokaryotes and eukaryotes differ in their chromosome structure; prokaryotes have a single circular chromosome, while eukaryotes have multiple circular chromosomes. Linear chromosomes are more complex than circular ones and create problems for eukaryotes. Many of these issues are solved by telomeres—long, repetitive sequences of DNA found on the ends of most eukaryotic chromosomes. They protect the ends from harm and limit how many times a cell can divide. Two of our greatest medical challenges, cancer and aging, are closely related to telomeres; most cancers upregulate telomerase, and aging human cells display shorter telomeres. To investigate the evolution and function ...


Photography Practicum: Learning The Basics Of Managing A Fine Art Photography Darkroom, Brooklin Routt, Allison Jones, Frazier Pack, Robyn Moore Apr 2022

Photography Practicum: Learning The Basics Of Managing A Fine Art Photography Darkroom, Brooklin Routt, Allison Jones, Frazier Pack, Robyn Moore

2022 Celebration of Student Scholarship - Poster Presentations

The photography practicum provides Art and Design student researchers with the practical experience of managing a fine art photography studio. Students learn how to operate, manage, and maintain industry-standard fine art archival inkjet printers as well as a fourteen-station traditional black and white darkroom. This project provides essential expertise and knowledge that students, as lab monitors, both share with other students and incorporate into their own fine art practice and professional activities. Student researchers learn how to mix, store, and dispose of photographic chemistry, provide daily assistance to undergraduate and graduate photography students, and generate ideas for improvements to the ...


Quantifying Ant Populations To Measure Biodiversity In Morehead, Ky, Alyssa Turner, Jude Hall, Tayla Lee, Charles Lydeard, Sean O'Keefe Apr 2022

Quantifying Ant Populations To Measure Biodiversity In Morehead, Ky, Alyssa Turner, Jude Hall, Tayla Lee, Charles Lydeard, Sean O'Keefe

2022 Celebration of Student Scholarship - Poster Presentations

To effectively conduct conservation efforts, we can use biodiversity to assess the condition of our environment. Biodiversity has been commonly defined as the variety and variability among living organisms within an area. When our ecosystems are at their best, they clean water, purify air, maintain soil, regulate climate, recycle nutrients, and provide food. Everything within an ecosystem is interdependent, so biodiversity is an important factor and indicator of environmental health. Indicators help us to measure and monitor pressures or threats in land and water use, habitat loss or invasive species, the state of species and ecosystems, the conservation response, and ...


Technology In Workplace Communication By Generation, Hannah Meadows, Christy Trent Apr 2022

Technology In Workplace Communication By Generation, Hannah Meadows, Christy Trent

2022 Celebration of Student Scholarship - Poster Presentations

The purpose of this research study was to determine the generational differences in the use of communication technology in the workplace. Most employees feel a deeper sense of connection to those in their own generational group. This survey looks at ideologies across four generations, Baby Boomers, Generation X, Millennials, and Generation Z, to help give employers some insight into why employees feel this way and encourage better communication in the workforce.


The Perception Of Minority Student-Athletes’ And Non-Athlete Students’ Learning Experience At A Predominately White Institution, William Wellman, Jelani Garvin, Jane Zhang, Steve Chen Apr 2022

The Perception Of Minority Student-Athletes’ And Non-Athlete Students’ Learning Experience At A Predominately White Institution, William Wellman, Jelani Garvin, Jane Zhang, Steve Chen

2022 Celebration of Student Scholarship - Poster Presentations

This study examined mainly African-American and minority students' learning experience at a regional public university in Appalachia for the purpose of improving the existing academic support services and creating a safe diverse learning environment for racial minority students.


Morphometrics Of The Rare Earwigfly Merope Tuber, Nicholas Finch, Sean O'Keefe Apr 2022

Morphometrics Of The Rare Earwigfly Merope Tuber, Nicholas Finch, Sean O'Keefe

2022 Celebration of Student Scholarship - Poster Presentations

Merope tuber Newman (Mecoptera: Meropeidae) is a rare North American species of earwigfly, which is closely related to common scorpionflies. “Earwigfly” refers to three different species: the Western Australian Austromerope poulton, the South American Austromerope brasiliensis, and finally, the Eastern North American Merope tuber. This last species was the focus of our study. Johnson’s 1995 study was based on 160 earwigflies, where he measured the female abdomen length, male and female forewing length, and male basistylus and dististylus length. In their 2014 study, based on 82 earwigflies, Skvarla, Hartshorn, and Dowling measured head width, pronotum width, forewing length, abdomen ...


Telomerase Activity Enhancement In Saccharomyces Cerevisiae, Mackenzie Neal, Hailey Rietz, Melissa Mefford Apr 2022

Telomerase Activity Enhancement In Saccharomyces Cerevisiae, Mackenzie Neal, Hailey Rietz, Melissa Mefford

2022 Celebration of Student Scholarship - Poster Presentations

Telomeres are located at the ends of eukaryotic linear chromosomes and are composed of repeated nucleotide sequences. One of their main functions is to protect chromosomal ends from being damaged. Telomeres cannot be completely copied during DNA replication so they gradually shorten during each replication cycle in what is known as the “end replication problem”. To counteract this problem, the RNA dependent enzyme complex telomerase works to extend telomeres and help protect the ends of chromosomes. Telomeres and the telomerase enzyme are heavily involved in the aging process and cancer progression. Telomeres gradually shorten with age and eventually become so ...


Genes Repressed After Dna Damage In Acinetobacter Baumannii Are Co-Regulated By Umudab And Ddrr, Mollee Flannigan, Xiaohong Li, Eric Rouchka, Deborah Cook, Janeele Hare Apr 2022

Genes Repressed After Dna Damage In Acinetobacter Baumannii Are Co-Regulated By Umudab And Ddrr, Mollee Flannigan, Xiaohong Li, Eric Rouchka, Deborah Cook, Janeele Hare

2022 Celebration of Student Scholarship - Poster Presentations

UmuDAb and DdrR coregulate error-prone polymerases in the multi-drug resistant opportunistic pathogen, Acinetobacter baumannii, by repressing polymerase expression until after DNA damage. New evidence indicates that these proteins may also regulate other genes that are repressed following DNA damage. We performed an in silico analysis of RNA-Seq data from wild-type, ddrR, and umuDAb mutant strains to examine the expression levels of genes repressed after DNA damage. We used two different algorithms to analyze Cuffnorm- and HTSeq normalized gene counts. This analysis revealed nineteen (CuffDiff) or twenty-nine (DESeq2) genes repressed in wild-type cells that were derepressed after DNA damage in either ...


Research, Testing, And Validation Of Small Satellite Designs: Cubesats, Cansats, Pocketqubes, And Femtosatellites, Jason A. Combs, Jose L. Garcia Apr 2022

Research, Testing, And Validation Of Small Satellite Designs: Cubesats, Cansats, Pocketqubes, And Femtosatellites, Jason A. Combs, Jose L. Garcia

2022 Celebration of Student Scholarship - Poster Presentations

The focus of this project, through research and testing, was to prepare various elements of small satellite experiential education curriculum. Rather than be constrained to the expensive and long-term timelines of a larger satellites, students can assemble, test, and operate various classes of small satellites in a valuable learning experience that will prepare them to work on larger projects. The true benefit of a PocketQube, CanSat, or femtosatellite is that they can be built with less money, less experience, and less long-term commitment while providing a scaled version of the real-life satellite development process that will engage and inspire students ...


Fungi In A Warmer World: Fungal Diversity In The Tropical Miocene Climate Optimum Of The Clarkia Region Of Idaho, Usa, J. Fairchild, L. Lennex-Stone, T. Horsfall, L. Tarlton, S. Jones, A. Caldwell, O. Vanderespt, L. Smallwood, A. Patel, J. O'Keefe, I. Romero, N. Nunnez Otano, M. Pound Apr 2022

Fungi In A Warmer World: Fungal Diversity In The Tropical Miocene Climate Optimum Of The Clarkia Region Of Idaho, Usa, J. Fairchild, L. Lennex-Stone, T. Horsfall, L. Tarlton, S. Jones, A. Caldwell, O. Vanderespt, L. Smallwood, A. Patel, J. O'Keefe, I. Romero, N. Nunnez Otano, M. Pound

2022 Celebration of Student Scholarship - Poster Presentations

A knowledge gap associated with how fungal communities change in response to climate was identified in the 2018 State of the World Fungi report (Willis, 2018). While it is virtually impossible to test in the present, fungal assemblage changes can be studied in sediments from a warmer-than-present period such as the Miocene Climate Optimum (MCO) (Romero et al. 2021; O’Keefe 2017). The Fungi in a Warmer World project aims to generate and analyze a global-scale data set of fungal biodiversity, ecology, and associated flora from MCO sediments. This dataset will be used to model past fungal assemblage changes across ...


Genes Involved In Cell Division In Acinetobacter Baumannii Are Coregulated By Umudab And Ddrr, Belinda Candra, Xiaohong Li, Eric Rouchka, Deborah Cook, Janelle Hare Apr 2022

Genes Involved In Cell Division In Acinetobacter Baumannii Are Coregulated By Umudab And Ddrr, Belinda Candra, Xiaohong Li, Eric Rouchka, Deborah Cook, Janelle Hare

2022 Celebration of Student Scholarship - Poster Presentations

In the presence of DNA damage, the multi-drug resistant bacteria Acinetobacter baumannii employs the proteins UmuDAb and DdrR to repress the expression of error-prone polymerases.


Novel Gain-Of-Function Mutations In The Telomerase Rna Of Saccharomyces Cerevisiae, Keenan Conley, Madison Frazier, Melissa Mefford Apr 2022

Novel Gain-Of-Function Mutations In The Telomerase Rna Of Saccharomyces Cerevisiae, Keenan Conley, Madison Frazier, Melissa Mefford

2022 Celebration of Student Scholarship - Poster Presentations

Yeast are eukaryotic organisms that contain liner chromosomes. At the ends of these chromosomes, there are special regions known as telomeres. Telomeres are composed of non-coding nucleotides that serve to protect the vital coding DNA found throughout the rest of the chromosome. During the process of DNA replication, however, telomeres become progressively shorter which can lead to cellular senescence. To solve this issue, yeast express the enzyme telomerase. Telomerase is composed of a telomerase reverse transcriptase protein (TERT) and telomerase RNA (TLC1) in yeast. When telomeres become too short, telomerase extends telomeres by adding to the 3’ overhang. Telomeres shorten ...


Seasonal Abundance And Sex Ratio Of Earwigflies (Merope Tuber) In Eastern Kentucky, Abigal Fagan, Sean O'Keefe Apr 2022

Seasonal Abundance And Sex Ratio Of Earwigflies (Merope Tuber) In Eastern Kentucky, Abigal Fagan, Sean O'Keefe

2022 Celebration of Student Scholarship - Poster Presentations

The earwigfly is a rarely seen insect in the family of scorpionflies. There are three species total, one in Brazil, one in Australia, and the third (Merope tuber), widespread throughout the eastern United states. In a 1984 study, Chris Maier collected 69 earwigflies between 1977 and 1982 from New England. Most of these were collected in July using sticky traps. He collected 43 females and 26 males (sex ratio 2.4:1). In a 2014 study, Skvarla, Hartshorn, and Dowling collected 77 earwigflies from Arkansas, mostly in August using malaise traps, pan traps, Lindgren funnels, and pitfall traps. They collected ...


College Students’ Knowledge And Use Of Herbal Supplements: Informed Decision, Health Risk, Or Marketing Ploy?, Jillian Wallshield, Wilson Gonzalez-Espada Apr 2022

College Students’ Knowledge And Use Of Herbal Supplements: Informed Decision, Health Risk, Or Marketing Ploy?, Jillian Wallshield, Wilson Gonzalez-Espada

2022 Celebration of Student Scholarship - Poster Presentations

The purpose of this study is to better understand the extent to which college students from Eastern Kentucky use Herbal Supplements (HS). The research questions for this study were:

• How do the participants find out about HS?

• How helpful do participants perceive the HS they take to be?

• What misconceptions do participants have regarding HS?

• Does a positive or negative attitude towards science change the usage rate of HS?


Drone Mapping On Eagle Lake Dam, Nathan Sparks, Timothy Hare Apr 2022

Drone Mapping On Eagle Lake Dam, Nathan Sparks, Timothy Hare

2022 Celebration of Student Scholarship - Poster Presentations

The Eagle Lake Dam is an iconic part of Morehead State’s campus. It can be seen from much of campus and serves as one of the best views around. It is also the single most important structure on campus. A significant percentage of the campus would be damaged or impaired, as well as many people would be endangered if the dam failed. Hence, I am starting a multi-person and multi-year initiative to monitor Eagle Lake Dam using UAV and remote sensing technology. I hope to have teams make annual 3D models of Eagle Lake Dam over the next several ...


Beetle Diversity Within Ecosystems; Insight Of The Order Coleoptera In The Eastern Kentucky Region, Blake Branham, Hannah Pyles, Charles Lydeard, Sean O'Keefe Apr 2022

Beetle Diversity Within Ecosystems; Insight Of The Order Coleoptera In The Eastern Kentucky Region, Blake Branham, Hannah Pyles, Charles Lydeard, Sean O'Keefe

2022 Celebration of Student Scholarship - Poster Presentations

Having a multitude of definitions, biodiversity can most commonly be seen as the variety and diversity of life within an ecosystem. Its relevance is crucial for species survival and resource availability; a lack of biodiversity sets an ecosystem up for failure, reducing its productivity, species richness, and increasing organismal vulnerability. Measuring biodiversity is crucial for the understanding of an ecosystem’s health, giving scientists knowledge of its stability, productivity, and persistence. This collected information can be implemented in various ways outside the scientific field as well, such as with policy decisions and legal regulations. Biodiversity is most commonly analyzed through ...


Frequency Of Genetic Variants At The Mc1r Locus In A Student Population, Emmalea K. Dowdy, Grace C. Stubblefield, David K. Peyton Apr 2022

Frequency Of Genetic Variants At The Mc1r Locus In A Student Population, Emmalea K. Dowdy, Grace C. Stubblefield, David K. Peyton

2022 Celebration of Student Scholarship - Poster Presentations

The Melanocortin-1 Receptor gene (MC1R) encodes a protein that is associated with pigmentation in vertebrate animals. An extraordinary number of variations in this gene have arisen over time due to the importance of pigmentation in camouflage, photosensitivity, vitamin D production, and other evolutionary factors. Variations in the MC1R gene sequence became important to survival as humans migrated out of Africa and into cooler climates with less sun exposure, where lighter skin pigmentation (and therefore more vitamin D production) was key to survival. These genetic variations (alleles) continue to exist in modern humans. Recent research into the MC1R gene variations shows ...


Pressure Ulcer Prevention: A Quality Improvement Project, Noah Blevins, Graci Borders, Brett Bentley, Carly Crutchfield, Rachel Dillion, Jacob Dyer, Heleigh Eldridge, Taylor Emmons, Suzi White Apr 2022

Pressure Ulcer Prevention: A Quality Improvement Project, Noah Blevins, Graci Borders, Brett Bentley, Carly Crutchfield, Rachel Dillion, Jacob Dyer, Heleigh Eldridge, Taylor Emmons, Suzi White

2022 Celebration of Student Scholarship - Poster Presentations

A pressure ulcer is an injury that affects the underlying tissue and skin and is primarily caused by prolonged pressure on the skin. During a clinical rotation at a small rural teaching hospital, pressure ulcers were prevalent in an estimated 80% of patients in the intensive care unit (ICU) during a three-week period. Approximately $26.8 billion are spent every year in the United States treating pressure ulcers. The purpose of this quality improvement project is to provide staff education to ICU nurses in order to reduce and prevent the prevalence of pressure ulcers in patients. A thorough literature review ...


Comfort Women: The Climax That Exposed Japanese Culture, Olivia Dale, James Masterson Apr 2022

Comfort Women: The Climax That Exposed Japanese Culture, Olivia Dale, James Masterson

2022 Celebration of Student Scholarship - Poster Presentations

When a nation attempts to erase the history of a marginalized group, the preservation of such narratives becomes critical. The genuine culture of a nation is exposed when that which officials attempted to hide is analyzed. The comfort women scheme conducted by the Imperial Japanese Government serves as an example of this phenomenon. The comfort women system was more than sex trafficking; it was the climax of a sexist society. Japan had a long history of organized prostitution before the Second World War, but during the conflict, the demeaning actions committed against women extended beyond the nation. The Japanese government ...


Encouraging Increased Ppe Compliance: A Quality Improvement Project, Christen Ballard, Hannah Carpenter, Skyler Harper, Angela Marcum, Suzi White Apr 2022

Encouraging Increased Ppe Compliance: A Quality Improvement Project, Christen Ballard, Hannah Carpenter, Skyler Harper, Angela Marcum, Suzi White

2022 Celebration of Student Scholarship - Poster Presentations

Personal protective equipment (PPE) is used to minimize infection transmission from patient to healthcare worker, or vice versa. During a clinical rotation in a large urban teaching hospital, it was noted that a number of nurses failed to adhere to proper PPE policies. A literature review focusing on thirty-two studies found that average nurse compliance to proper PPE is 34%. This review included an overall discussion of factors affecting compliance, as well as a more in-depth review of the effect of education on PPE compliance, how comfort and proper fitting affects compliance, and the general effectiveness of PPE when used ...