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Articles 1 - 30 of 98
Full-Text Articles in Life Sciences
Elucidating The Role Of Dopamine In The Avoidance Response Of Caenorhabditis Elegans Utilizing Microfluidics, Patricia Frances Turturro
Elucidating The Role Of Dopamine In The Avoidance Response Of Caenorhabditis Elegans Utilizing Microfluidics, Patricia Frances Turturro
Theses Digitization Project
This study looks at dopamine modulation of ASH neurons, which are part of the avoidance circuit of C. elegans, and their response to water soluble stimuli. Because nematodes such as Caenorhabditis elegans utilize dopamine at the molecular and cellular level in much the same way as mammals, they offer researchers a unique opportunity to study the mechanisms of dopamine signaling.
Dopaminergic Modulation Of Glutamate Signaling In Caenorhabditis Elegans, Melvin Suman Baidya
Dopaminergic Modulation Of Glutamate Signaling In Caenorhabditis Elegans, Melvin Suman Baidya
Theses Digitization Project
This study investigates how DA (dopamine) modulates GLU (glutamate) signaling at the interneuron level of the C. elegans avoidance circuit in response to the noxious chemical 1-octanol. Many neural processes involved in addiction, exhibit cellular mechanisms using the neurotransmitters dopamine and glutamate along with their intracellular and genomic targets.
Cell Type Difference In Influenza A Viral Mrna Nuclear Export, Sean William Larsen
Cell Type Difference In Influenza A Viral Mrna Nuclear Export, Sean William Larsen
Theses Digitization Project
The focus of this thesis research was to clarify the role of host Nxf1 in influenza viral mRNA nuclear export. This study aims to define the nuclear mRNA export pathways of influenza viral mRNA. If viral mRNAs are discovered to utilize neither known mRNA nuclear export pathway this would indicate the mRNA exports via undefined mRNA nuclear export pathway. This might be an atypical pathway not utilized by many host mRNAs and thus might reveal novel antiviral target. 293T (Human embryonic kidney cells) and A549 (Human lung epithelial) cells were purchased from ATCC American Tissue Culture Collection.
Postcranial Description And Reconstruction Of The Varanodontine Varanopid Aerosaurus Wellesi (Synapsida: Eupelycosauria), Valerie Ann Pelletier
Postcranial Description And Reconstruction Of The Varanodontine Varanopid Aerosaurus Wellesi (Synapsida: Eupelycosauria), Valerie Ann Pelletier
Theses Digitization Project
The postcranial skeleton of the varanopid synapsid aerosaurus wellesi is reconstructed based on several specimens including partly articulated material of an apparently fully adult specimen. Comparisons are made with other known varanopid taxa, reaffirming its position as a basal varanondontine.
Variable Levels Of Atmospheric Oxygen Do Not Affect Microanatomy And Limb Bone Geometry In Alligator Mississippiensis, Susan Lee Lujan
Variable Levels Of Atmospheric Oxygen Do Not Affect Microanatomy And Limb Bone Geometry In Alligator Mississippiensis, Susan Lee Lujan
Theses Digitization Project
Striking changes in atmospheric oxygen levels have occured since the beginning of the Phanerozic 542 million years ago. Alligators belong to a clade of vertebrates with a long evolutionary history spanning much of this variability in atmospheric oxygen. An investigation into the effects of hypoxia and hyperoxia on skeletal growth and physiology in alligators may help to reconstruct the life history of archosaurs, explain patterns in the fossil record, and broaden our understanding of the processes underlying long term success of this clade.
Genetic Analysis Of The Gene Varpa_4519 Encoding A Nonribosomal Peptide Synthetase Crucial For Surfactant Production In Variovorax Paradoxus Eps, Richard John Fredendall
Genetic Analysis Of The Gene Varpa_4519 Encoding A Nonribosomal Peptide Synthetase Crucial For Surfactant Production In Variovorax Paradoxus Eps, Richard John Fredendall
Theses Digitization Project
This study investigated swarming by Variovoras paradoxus EPS to understand the genes involved and the mechanisms for swarming motility. Swarming motility is defined as a movement on a surface requiring surfactant and flagella. Swarming is a differentiation process in which bacteria enter into an excited state of constant movement. The mechanism for swarming is driven by nutrient factors, and is not based on specific development stages of the bacterial life cycle.
Elucidating The Role Of Bone Morphogenetic Proteins And B-Lymphocyte Maturation Protein 1 During Primordial Germ Cell Specification, Laughing Bear Torrez Dulgeroff
Elucidating The Role Of Bone Morphogenetic Proteins And B-Lymphocyte Maturation Protein 1 During Primordial Germ Cell Specification, Laughing Bear Torrez Dulgeroff
Theses Digitization Project
This study will present an optimized protocol to induce and isolate primordial germ cells (PGC) from hESC and hiPSC. Human embrionic stem cells (hESC and induced pluripotent stem cells (iPSC) provide a model for studying paradigms of early development.
Limb Bone Geometry And Skeletal Physiology In Mice Bred For High Levels Of Activity, Brittney Racheal Coats
Limb Bone Geometry And Skeletal Physiology In Mice Bred For High Levels Of Activity, Brittney Racheal Coats
Theses Digitization Project
The studies presented here evaluate the effects of exercise and genetics on biomechanically important traits and the skeletal system's role in maintaining proper metabolic health. The goal of the project presented here is to further our understanding of the leptin-bone-insulin pathway and relevant changes that may occur in this pathway as a result of exercise. Cross-sectional analyses of HR mice and control mice allowed or denied wheel access for 10 weeks, revealed significant differences in biomechanical properties.
Elucidating The Effects Of Tobacco Products On Skeletal Development, Nicole Renee Sparks
Elucidating The Effects Of Tobacco Products On Skeletal Development, Nicole Renee Sparks
Theses Digitization Project
The overall goal of this thesis project is to characterize the molecular mechanisms of tobacco product induced skeletal teratogenicity.
A Positive Correlation Between Imagery And Athletic Performance, Erik Lee Foor
A Positive Correlation Between Imagery And Athletic Performance, Erik Lee Foor
Theses Digitization Project
The main purpose of this project was to present to other athletes and coaches an unconventional form of practice; the utilization of imagery and how it can lead to improved athletic performance in many different sports including tennis, golf, cross-country, basketball, track & field gymnastics, diving, soccer and weight-lifting. This project analyzed multiple studies in which the use of imagery was tested among a number of athletes during different sports activities. The data was evaluated to show the positive effects of imagery and visual motor behavior rehearsal (VMBR) as a whole on athletes. A total of 25 peer-reviewed articles were …
Feather Biomechanics Of Penguins And Other Seabirds, Katherine Elizabeth Johnson
Feather Biomechanics Of Penguins And Other Seabirds, Katherine Elizabeth Johnson
Theses Digitization Project
Although many aspects of penguin biology have been studied, the feathers have received less attention except with regard to thermoregulation. The biomechanics of penguin feathers are the focus of this thesis. By studying penguins in comparison to other wing-propelled aquatic fliers, it may be possible to understand how penguin feathers evolved. Fourteen species were sampled, including aerial flyers, aerial flyers that are also wing propelled divers, as well as flightless wing propelled divers.
Influenza Nucleoprotein Interactions As Potential Antiviral Targets, Abel Sanchez
Influenza Nucleoprotein Interactions As Potential Antiviral Targets, Abel Sanchez
Theses Digitization Project
The purpose of this research was to investigate the Nucleoprotein (NP) RNA dependent RNA polymerase (RdRP) interaction by identifying and characterizing a NP mutant which maintains RNA binding but is unable to interact with the viral polymerase complex. Influenza poses a threat to human health and is a burden on the global economy. Influenza is caused by influenza virus which contains a segmented RNA genome, resulting in rapid evolution and emergence of new influenza subtypes which lead to pandemics.
An Evolutionary Psychology Perspective On Responsibility Attributions For Infidelity And Relationship Dissolution, Kindra Lynn Edmonson
An Evolutionary Psychology Perspective On Responsibility Attributions For Infidelity And Relationship Dissolution, Kindra Lynn Edmonson
Theses Digitization Project
This study investigated responsibility attributions for a partner's emotional infidelity and for a partner's sexual infidelity, and the likelyhood that the victim or partner would end the relationship. This study found a significant relationship between responsibility attributions for a romantic partner's unfaithfulness and the likelihood the relationship would end: the stronger the attributions of personal responsibility the more likely the relationship would dissolve.
Genetic Analysis Of Two Phenotypes In Variovorax Paradoxus Strain Eps, Michael Jherek Pehl
Genetic Analysis Of Two Phenotypes In Variovorax Paradoxus Strain Eps, Michael Jherek Pehl
Theses Digitization Project
The formation of biofilms is a complex process that involves activation of a wide array of genetic material within the cells found living within the biofilm. It has been shown that altered colony morphology has been associated with different biofilm levels within P. aureginosa. This analysis will provide further evidence of the strength of the colony morphology screen to isolate mutants with altered biofilm or swarming abilities.
Alpine Ecology Of A C4 Grass, Muhlenbergia Richardsonis In The White Mountains Of California, Archie Thomas Meyer
Alpine Ecology Of A C4 Grass, Muhlenbergia Richardsonis In The White Mountains Of California, Archie Thomas Meyer
Theses Digitization Project
The purpose of this thesis was to understand how this unusual C₄ alpine grass, Muhlenbergia Richardsonis, persists in the alpine zone along the western slope of California's White Mountains.
The Effects Of Leptin And Thyroid Hormone On Metabolism And Lipid Trafficking In The Liver And Adipose Tissue Of Ob/Ob Mice, Candace Michelle Reno
The Effects Of Leptin And Thyroid Hormone On Metabolism And Lipid Trafficking In The Liver And Adipose Tissue Of Ob/Ob Mice, Candace Michelle Reno
Theses Digitization Project
The purpose of this project was to study how the key metabolic hormones, insulin, leptin, and thyroid hormone alter metabolic pathways and lipid and glucose trafficking in order to find possible therapies for treatment for obesity and its complications.
Comparative Osteohistology Of Hyperelongate Neural Spines In Basal Synapsids (Vertebrata, Amniota): Growth And Mechanical Considerations, Adam Keith Huttenlocker
Comparative Osteohistology Of Hyperelongate Neural Spines In Basal Synapsids (Vertebrata, Amniota): Growth And Mechanical Considerations, Adam Keith Huttenlocker
Theses Digitization Project
Basal synapsids comprise one of the best represented groups of early tetrapods and demonstrate a classic example of a macroevolutionary transition. The basal synapsid fossil record is of significant interest to paleontolists because it presents an excellent opportunity for studying the evolution of vertebrate morphology. In the present study, neural spine osteohistology is further examined across a broad range of basal synapsid genera with hyperlongate neural spines. Due to the limited availability of specimens and the comparative approach required for destructive analysis, the present study is divided into two major comparative investigations: analysis of hyperlongate neural spine in (1) Spenacodontidae …
Effects Of Natural History On Osmoregulatory Behaviors In Two Stream-Dwelling Frogs (Pseudacris Cadaverina And P. Regilla), Heidy Lorena Contreras
Effects Of Natural History On Osmoregulatory Behaviors In Two Stream-Dwelling Frogs (Pseudacris Cadaverina And P. Regilla), Heidy Lorena Contreras
Theses Digitization Project
Differences in osmoregulatory behaviors were studied in two stream-dwelling tree frogs (Pseudacris cadaverina and P. regilla) with different natural histories. This study supports the idea that the natural history of a species has a strong effect on behavior associated with osmoregulation.
A Geographically Constrained Molecular Phylogeny Of Panamanian Aechmea Species (Bromeliaceae, Subfamily Bromelioideae), Keri Renee Maher
A Geographically Constrained Molecular Phylogeny Of Panamanian Aechmea Species (Bromeliaceae, Subfamily Bromelioideae), Keri Renee Maher
Theses Digitization Project
This study lends strong support to the idea that members of Bromeliaceae have undergone a recent adaptive radiation, and therefore show that, at least in part, diversity in the tropics is due to a fast speciation rate and that the tropics can be a "cradle" for new diversification and exploitation of varying ecological niches through the diversification of ecophysiological traits within a lineage.
Population Genetics And Phylogeography Of The Pygmy Nuthatch In Southern California, Thomas Alan Benson
Population Genetics And Phylogeography Of The Pygmy Nuthatch In Southern California, Thomas Alan Benson
Theses Digitization Project
Uses mitochondrial DNA sequence data to examine the degree of genetic differentiation among sky island populations of two subspecies of pygmy nuthatch (Sitta pygmaea melanotis and Sitta pygmaea leuconucha) occurring in Southern California. Assesses the hypothesis that sky islands are genetically isolated and that migration (gene flow) is restricted among them. Eleven sampling locations throughout Southern California were selected based on representation of subspecies, availability of specimens, and feasibility of collection. Results indicate that pygmy nuthatch populations fragmented in the disjunct mountain ranges of Southern California exhibit low but significant levels of genetic differentiation.
Gender Differences In Anterior Cruciate Ligament Injuries, Carey Ann Balderrama
Gender Differences In Anterior Cruciate Ligament Injuries, Carey Ann Balderrama
Theses Digitization Project
The purpose of this study is to examine the existing literature on ACL (Anterior Cruciate Ligament) injuries as it pertains to gender. The study identifies current strategies for prevention of such injuries and outlines existing thinking on injury prevention programs.
Factors Influencing Purchasing Decision Process Of Low-Carbohydrate Products, Warintra Triyangkulsri
Factors Influencing Purchasing Decision Process Of Low-Carbohydrate Products, Warintra Triyangkulsri
Theses Digitization Project
The purpose of this study was to determine attitudes toward low carbohydrate diets among consumers and the attributes that influence their purchase decision. A growing number of diet trends are spreading across the nation in an effort to improve health and lose weight such as the Atkins diet and the South Beach diet.
Analysis Of Molecular Variation In The Federally Endangered Astragalus Jaegerianus (Fabaceae, Papilionoideae): A Species With A Restricted Geographic Range, George Floyd Walker
Analysis Of Molecular Variation In The Federally Endangered Astragalus Jaegerianus (Fabaceae, Papilionoideae): A Species With A Restricted Geographic Range, George Floyd Walker
Theses Digitization Project
The purpose of this study is to investigate the level and distribution of genetic variation in Astragalus jaegerianus by using molecular markers. The objectives of the study are: to estimate levels of genetic variation within and among populations of Astragalus jaegerianus; to test the hypothesis that levels and patterns of genetic variation in species of restricted ranges and few individuals is low and partitioned at the population level; and to discern whether, or how well, genetic partitioning of Lane Mountain milk vetch correlates with its geographic partitioning in the field.
Parental Perceptions Of Their Child's Weight And Health, Julie Vy Pham
Parental Perceptions Of Their Child's Weight And Health, Julie Vy Pham
Theses Digitization Project
Childhood obesity is a major health problem facing children in the United States. How parents view their children's weight is an important consideration for health care professionals. The purpose of this study was to explore parental perceptions of their children's weight and health.
The Underwater Life Off The Coast Of Southern California, Kathie Lyn Purkey
The Underwater Life Off The Coast Of Southern California, Kathie Lyn Purkey
Theses Digitization Project
This project reviews the basic chemical and geographical features of the ocean, biological classification of marine life, background of the ocean's flora and fauna, and the ocean's environment. These facts are presented through an underwater documentary filmed at various sites along Southern California's coast and complemented with lesson plans designed for grades K - 4.
Smart Sequence Similarity Search (S⁴) System, Zhuo Chen
Smart Sequence Similarity Search (S⁴) System, Zhuo Chen
Theses Digitization Project
Sequence similarity searching is commonly used to help clarify the biochemical and physiological features of newly discovered genes or proteins. An efficient similarity search relies on the choice of tools and their associated subprograms and numerous parameter settings. To assist researchers in selecting optimal programs and parameter settings for efficient sequence similarity searches, the web-based expert system, Smart Sequence Similarity Search (S4) was developed.
Improving Vertical Jump: A Program Design, Micheal Milo Horton
Improving Vertical Jump: A Program Design, Micheal Milo Horton
Theses Digitization Project
The purpose of this project is to review current literature on the mechanics and physiology of the vertical jump and to provide an understanding of the jump itself. The second purpose is to develop a step by step program to increase vertical jump from grade school through high school.
The Postcranial Skeleton Of The Family Limnoscelidae And Its Taxonomic Implications For Understanding Basal Amniotes, Natalia Kazimiera Wideman
The Postcranial Skeleton Of The Family Limnoscelidae And Its Taxonomic Implications For Understanding Basal Amniotes, Natalia Kazimiera Wideman
Theses Digitization Project
The Diadectomorpha is a central taxon in understanding the origin and early evolution of amniotes. It is considered a sister taxon to Amniota and is so similar to amniotes that some researchers have placed it within the Amniota itself. This group is composed of three families: the Limnoscelidae, the Tseajaiidae, and the Diadectidae. Being the most basal member of this group, the family Limnoscelidae is especially important in these studies.
Using The Polymerase Chain Reaction To Determine The Prevalence Of Lyme Disease Bacteria, Borrelia Burgdorferi, In Ixodes Pacificus Ticks From San Bernardino County In Southern California, Richard Allen
Theses Digitization Project
The purpose of this study was to determine the prevalence of Lyme Disease (LD) bacteria in adult Ixodes pacificus ticks collected from the mountains of San Bernardino County in Southern California. Seven hundred fifty four I. pacificus adults were collected from the Pacific Crest Trail and adjacent areas. The Polymerase Chain Reaction (PCR) was used to screen ticks for Borrelia burgdorferi infection by targeting two different DNA loci. Oligonucleotide primers targeting both the ospA and fla genes were used in the assay. Ticks were processed in pools of three, and genomic DNA from the ticks was extracted with a commercial …
The Effects Of R-Flurbiprofen In Reducing Tumors In A Multiple Intestinal Neoplasia Mouse Model, David Douglas Quiggle
The Effects Of R-Flurbiprofen In Reducing Tumors In A Multiple Intestinal Neoplasia Mouse Model, David Douglas Quiggle
Theses Digitization Project
The design of the proposed study was to administer R-FB to 72-day old Min/+ mice for up to 42 days. In order to capture the process of tumor reduction, animals were necropsied at various time points. At each time point animals were evaluated for tumor loads and presence of apoptotic cells along the small intestine. Studies have shown that when R-flurbiprofen (R-FB) is administered in the Min/+ mouse model it can cause the prevention and regression on intestinal tumors.