Open Access. Powered by Scholars. Published by Universities.®
Articles 1 - 14 of 14
Full-Text Articles in Life Sciences
The Genetics Of Skin Cancer: What Genes Drive The Development Of Basal Cell Carcinoma, Squamous Cell Carcinoma, And Melanoma?, Cassandra Poole, Abagail Pack, Elizabeth Whitehead, Virginia Marshall
The Genetics Of Skin Cancer: What Genes Drive The Development Of Basal Cell Carcinoma, Squamous Cell Carcinoma, And Melanoma?, Cassandra Poole, Abagail Pack, Elizabeth Whitehead, Virginia Marshall
Spring Showcase for Research and Creative Inquiry
Skin cancer is one of the most common forms of cancer worldwide. The American Academy of Dermatology estimates that 9500 people in the United States are diagnosed with skin cancer every day, and that 1 in 5 Americans will be diagnosed with skin cancer by age 70. With such a high prevalence of disease, understanding how skin cancer develops and how it can be treated is extremely important. This project aims to analyze the genes involved in the development of the three most common forms of skin cancer: basal cell carcinoma, squamous cell carcinoma, and melanoma.
Comparing Expression Of Green Fluorescent Protein (Gfp) With Different Plasmids, Tinsae Alem, Charles Curbeam, Mackenzie Woody
Comparing Expression Of Green Fluorescent Protein (Gfp) With Different Plasmids, Tinsae Alem, Charles Curbeam, Mackenzie Woody
Spring Showcase for Research and Creative Inquiry
How do different plasmids carrying different promoters affect the Green Fluorescent Protein (GFP) expression? If the appropriate promoter is not used within the bacterias, then the bacterias will not be able to survive and glow.
Techniques Learned By Students To Determine Which Agar Coated Plates Will Show Bacterial Growth And Glow., Lilly Rogers, Hannah Spencer
Techniques Learned By Students To Determine Which Agar Coated Plates Will Show Bacterial Growth And Glow., Lilly Rogers, Hannah Spencer
Spring Showcase for Research and Creative Inquiry
The process in which students conducted a series of experiments to find if agar plates would produce the GFP gene.
The Transformation Of E. Coli Using The Pglo Plasmid, Hailee Banks, Kira Edens
The Transformation Of E. Coli Using The Pglo Plasmid, Hailee Banks, Kira Edens
Spring Showcase for Research and Creative Inquiry
The experiment was based on taking E. coli and transforming those cells using pGLO plasmid. It was questioned whether colonies will grow after genetic modification using GFP and if so, will the colonies present a fluorescent green glow. With the consideration of GFP and pGLO being normally associated with each other, it was hypothesized that the colonies will present a fluorescent green glow after using biotechnology processes. This experimental process undergone various steps to successfully verify the presence of GFP and then transform the E. coli. PCR amplicon via gel electrophoresis, purification of amplicon sequence, and transformation using agar plates …
Encouraging Public Outreach And Education To Drive Covid-19 Vaccination In Farmville, Grace Freeman, Marcia Lanasa, Mitchell Sharry
Encouraging Public Outreach And Education To Drive Covid-19 Vaccination In Farmville, Grace Freeman, Marcia Lanasa, Mitchell Sharry
Spring Showcase for Research and Creative Inquiry
As part of our Biology Capstone, we have created a white paper to communicate the importance of public outreach and education regarding the current COVID-19 vaccines to the Farmville Town Council. Previous research has shown that available vaccinations help to prevent the spread of the COVID-19 virus and highlights the importance of widespread community vaccination. Our recommendation to the Farmville Town Council is to create an educational campaign to encourage vaccination within the Farmville community.
Transformation Of E. Coli And Regulation Of Gfp In Pglo, Melanie Rowland, Emily Edwards
Transformation Of E. Coli And Regulation Of Gfp In Pglo, Melanie Rowland, Emily Edwards
Spring Showcase for Research and Creative Inquiry
Research Question: Will the presence of pGLO plasmid containing GFP gene produce glowing cells? Hypothesis: In the presence of pGLO plasmid containing GFP gene, the production of glowing cells will occur.
The Abundance Of Soil Microbes In Relationship To Proximity To The Urban Area Of Lancer Park In Farmville, Virginia, Christian Michael, Callie Cutrell, Miguel Diaz-Montealegre
The Abundance Of Soil Microbes In Relationship To Proximity To The Urban Area Of Lancer Park In Farmville, Virginia, Christian Michael, Callie Cutrell, Miguel Diaz-Montealegre
Spring Showcase for Research and Creative Inquiry
Soil microbes are microorganisms found in soil that serve various critical roles and functions in the environment, such as decomposition and the cycling of nutrients in ecosystems. Natural and human-caused factors can have positive and/or negative impacts on soil microbes. The objective of this study is to examine the abundance of soil microbes in relationship to proximity to the urban area of Lancer Park in Farmville, Virginia. Soil samples were taken from four locations within Lancer Park: the upper and lower floodplain of Buffalo Creek, the bottom of a large stormwater detention pond, and adjacent to an ephemeral channel connecting …
Combined Effects Of Allelochemical And Pesticide Treatment On The Growth Of Cucumber Plants, Samue Morgan
Combined Effects Of Allelochemical And Pesticide Treatment On The Growth Of Cucumber Plants, Samue Morgan
Spring Showcase for Research and Creative Inquiry
Allelochemicals are biochemicals produced by one plant that inhibits the success of other plants in its vicinity. These allelochemicals are sometimes produced naturally or as a result of stimulus or stress. Ferulic acid is a widespread allelochemical found in cucumbers (Cucumis sativus). Artificial inhibitory chemicals such as the pesticide zeta cypermethrin may create new interactions with ferulic acid. We found that cucumbers acclimate to ferulic acid over time while the inhibitory effects of pesticide remained relatively constant over 14 days.
Activating The Innate Immune Response By Utilizing Macrophages As Aâ Defense For Immunosuppressed Individuals And Covid-19, Ashley Coddington, Christina Amoruso, Emma Rogers
Activating The Innate Immune Response By Utilizing Macrophages As Aâ Defense For Immunosuppressed Individuals And Covid-19, Ashley Coddington, Christina Amoruso, Emma Rogers
Spring Showcase for Research and Creative Inquiry
The activation of the innate immune response by utilizing Interferon-Gamma to activate macrophages will provide for immunosuppressed individuals an additional treatment option for COVID-19.
Covid-19 Vaccine Distribution For The Homeless Population In Virginia, Brandi Joyner, Hunter Gillespie, Terika Williams
Covid-19 Vaccine Distribution For The Homeless Population In Virginia, Brandi Joyner, Hunter Gillespie, Terika Williams
Spring Showcase for Research and Creative Inquiry
Due to the lack of proper personal hygiene, clean water and housing, the homeless population is more susceptible to infections. In addition, the homeless are more likely to have compromised immune systems (i.e., HIV/AIDS) due to illicit drug use and sex work. Furthermore, there is not a current systematic state program that allows feasible access to the COVID-19 vaccine due to limited internet access and/or phone access. We are proposing that the Virginia House of Delegates provide state funding for vaccination drives in areas with high poverty rates. Locations can be at soup kitchens, food banks, domestic abuse shelters, and …
Which Weather And Water Conditions Affect The Biodiversity And Abundance Of Macroinvertebrates The Most?, Alyssa Oppedisano, Phil Anderson, Val Phillips
Which Weather And Water Conditions Affect The Biodiversity And Abundance Of Macroinvertebrates The Most?, Alyssa Oppedisano, Phil Anderson, Val Phillips
Spring Showcase for Research and Creative Inquiry
Macroinvertebrates are important biological monitors that play a valuable role in the metabolism of freshwater food chains. Previous studies have suggested that conditions such as dissolved oxygen, pH, water temperature, precipitation, and air temperature can affect the abundance of macroinvertebrates which can in turn affect the health of freshwater ecosystems. This research aimed to find the relationship between macroinvertebrate biodiversity and various environmental conditions in freshwater ecosystems. Weather data was taken from a weather station at Lancer Park and water data was taken on-site at Wilson stream, both locations in Farmville, Virginia. Sample collection and identification occurred twice a week …
Investigating The Effects Of Cancer Mutations On The Activity Of P300, Meghan Hall
Investigating The Effects Of Cancer Mutations On The Activity Of P300, Meghan Hall
Spring Showcase for Research and Creative Inquiry
Investigating the effects of cancer mutations on the activity of p300
The Use Hela Derived Telomerase On Nk Cells In The Treatment Of Ovarian Cancer, Juwairyah Gunter
The Use Hela Derived Telomerase On Nk Cells In The Treatment Of Ovarian Cancer, Juwairyah Gunter
Spring Showcase for Research and Creative Inquiry
A research proposal for a novel immunotherapy for treating ovarian cancer.
Ability Of Flavonoids To Mimic The Estrogen Receptor To Drive Myeloid Derived Suppressor Cell Differentiation, Megan Bland, Cecilie Elliott, Kathryn Kosiorek
Ability Of Flavonoids To Mimic The Estrogen Receptor To Drive Myeloid Derived Suppressor Cell Differentiation, Megan Bland, Cecilie Elliott, Kathryn Kosiorek
Spring Showcase for Research and Creative Inquiry
Flavonoids are natural compounds found in dietary elements such as soy, grains, and vegetables that have the potential to bind to the estrogen receptor. Activation of the estrogen receptor drives myeloid derived suppressor cell (MDSC) accumulation, cells that increase during cancer, inflammation, and infection. In this study, we are investigating specific flavonoids, such as epigallocatechin-3-gallate (EGCG), kaempferol, naringenin, daidzein, and genistein, for their ability to mimic estrogen. After examination, we expect that MDSC differentiation will decrease upon treatment of the chosen flavonoids, leading to reduced carcinogenic effects.