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Full-Text Articles in Life Sciences

How Does Antibiotic Resistance Spread In Tuberculosis?, Julie A. Spencer Nov 2018

How Does Antibiotic Resistance Spread In Tuberculosis?, Julie A. Spencer

Shared Knowledge Conference

The ancient bacterial disease of tuberculosis (TB) is curable with antibiotics, but according to the World Health Organization, in 2016 over 10 million people became infected with the disease. 600,000 of these cases were resistant to antibiotics, yet the worldwide treatment success rate for drug resistant TB is only 54%. Furthermore, strains exist now that are resistant to all known antibiotics. In the current environment of global travel, this poses a risk for emergent epidemics of drug resistant TB. In this study, I asked: after an antibiotic resistant strain has evolved in someone’s lungs, how does it spread? It is …


Ponderosa Pine Seedling Physiology After Severe Wildfire: Does It Take A Forest To Make A Forest?, Lauren Bansbach Nov 2018

Ponderosa Pine Seedling Physiology After Severe Wildfire: Does It Take A Forest To Make A Forest?, Lauren Bansbach

Shared Knowledge Conference

Ponderosa pine forests are an iconic ecosystem of western North America and provide numerous ecological, economic, and cultural benefits. Historically, these forests experienced regular surface fires that left most large, mature trees surviving. However, suppression of wildfires along with a warming climate have led to catastrophic tree-killing fires that result in vast areas (>200 mi2) dominated by shrubs and grasses. Because of limited survival of tree seedlings in these post-fire habitats, it remains unknown whether ponderosa pines can successfully recolonize severely burned landscapes. Without a mature tree canopy to provide periodic shade, seedlings experience hotter, drier conditions and likely …


The Paradoxical Giant Hummingbird: Comparison Of Andean And Coastal Subspecies With Respect To Blood, Migration, And Genes, Jessie L. Williamson Nov 2018

The Paradoxical Giant Hummingbird: Comparison Of Andean And Coastal Subspecies With Respect To Blood, Migration, And Genes, Jessie L. Williamson

Shared Knowledge Conference

The Giant Hummingbird (Patagona gigas) is twice as large as the next largest hummingbird species and has long been considered paradoxical with respect to flight biomechanics. It is also an extreme outlier in other respects. For example, it is the only hummingbird species that breeds above 4,000 m elevation and also along the beaches of the Pacific Ocean. The high Andean populations of Giant Hummingbird (P. g. peruviana) that we have studied previously have a beta-hemoglobin genotype (serine at beta-hemoglobin A positions 13 and 83) that is characterized by high O2-affinity and is only shared with four unrelated hummingbird taxa …


Assessing Water Policy Implications Of The Changing Agriculture In New Mexico, Trevor A. Birt Nov 2018

Assessing Water Policy Implications Of The Changing Agriculture In New Mexico, Trevor A. Birt

Shared Knowledge Conference

Agriculture is the dominant water sector in New Mexico, responsible for more than 80% of water withdrawals in 2015 (USGS 2018). Water policy needs to be extremely adaptive and informed to meet the needs of not only farmers, but cities, industry and riparian uses. Since 1840, the U.S. Department of Agriculture (USDA) has conducted census surveys assessing all levels of agriculture. These data are physically published at the county, state, and national level on a 5-year cycle, detailing various material counts such as acreage, yields, and water usage, as well as socioeconomic estimates of farm costs, revenues, and hired workers. …


Rainfall Changes Alter Plant Communities In Chihuahuan Desert Grasslands, Timothy Ohlert Nov 2018

Rainfall Changes Alter Plant Communities In Chihuahuan Desert Grasslands, Timothy Ohlert

Shared Knowledge Conference

Variations in New Mexico’s climate have been detected over the past century and are expected to continue into the future. Some of these climatic changes result in more frequent instances of extreme drought events and alterations of monsoon seasonality, with monsoons being pushed later into the fall. Such changes could make our Chihuahuan Desert plant communities less productive, shift the abundance of the plant species, or have other destabilizing impacts. Our experiment manipulated precipitation in two desert grassland communities at the Sevilleta National Wildlife Refuge near Socorro, NM. Some plots were subjected to an extreme drought event, receiving only 33% …


Engage A Voice, Repress Fatigue; The Coincident Evolution Of Hominin Vocalization And A Metabolic Threshold, Galen A. Morton 9935238, Martin L. Morton Nov 2018

Engage A Voice, Repress Fatigue; The Coincident Evolution Of Hominin Vocalization And A Metabolic Threshold, Galen A. Morton 9935238, Martin L. Morton

Shared Knowledge Conference

Physiologically self-protective mechanisms borne from hominin evolutionary history that increase survivability are not unknown to science. In reviewing exercise science literature regarding testing and assessment measures of subjects talking while exercising, a logical question has materialized: To what degree has evolution facilitated synchronization of comfortable oral communication with sustainable exercise intensity? An individual able to engage a voice, represses fatigue. The Talk Test, is a practical strategy whereby a subject deliberately speaks during an exercise protocol. It is a common tool in both kinesiology and clinical fields because it inherently identifies a pivotal metabolic threshold. The coincidence of comfortable ability …


Combined High-Speed Single Particle Tracking Of Membrane Proteins And Super-Resolution Of Membrane-Associated Structures, Hanieh Mazloom Farsibaf, Keith A. Lidke Nov 2018

Combined High-Speed Single Particle Tracking Of Membrane Proteins And Super-Resolution Of Membrane-Associated Structures, Hanieh Mazloom Farsibaf, Keith A. Lidke

Shared Knowledge Conference

Many experiments have shown that the diffusive motion of lipids and membrane proteins are slower on the cell surface than those in artificial lipid bilayers or blebs. One hypothesis that may partially explain this mystery is the effect of the cytoskeleton structures on the protein dynamics. A model proposed by Kusumi [1] is the Fence-Picket Model which describes the cell membrane as a set of compartment regions, each ~ 10 to 200 nm in size, created by direct or indirect interaction of lipids and proteins with actin filaments just below the membrane. To test this hypothesis, we have assembled a …


Temporal Information Guides Prefrontal Preparatory Activity, Jacqueline R. Janowich Nov 2018

Temporal Information Guides Prefrontal Preparatory Activity, Jacqueline R. Janowich

Shared Knowledge Conference

Proactive preparation for an upcoming goal differs from last-minute reactive adaptation, but it is unclear how preparatory mechanisms change based on when in the future a goal needs to be executed. To assess how timing information is integrated into preparatory control, we designed a novel variant of the Dot Pattern Expectancy task, where each cue signaled both task rule and delay duration (known short, known long, or unknown) between cue and probe. We recorded EEG while healthy young adult participants (n=36) performed this task, and found that delay demands elicited distinct prefrontal preparatory activities. Medial prefrontal amplitude was sensitive to …


Mechanisms For The Spread Of Antibiotic Resistance In Tuberculosis, Julie Allison Spencer Nov 2018

Mechanisms For The Spread Of Antibiotic Resistance In Tuberculosis, Julie Allison Spencer

Shared Knowledge Conference

Tuberculosis (TB) is currently the ninth leading cause of death for humans worldwide, causing 10.4 million new infections in 2016. According to the World Health Organization, of these infections, 600,000 were antibiotic resistant. However, the treatment success rate for resistant TB was only 54%. The potential for emergent epidemics of drug resistant TB highlights the need to understand the mechanisms for the spread of resistance. Mycobacterium tuberculosis, the bacterium that causes TB, evolves resistant strains within individuals who are being treated with antibiotics. It has been assumed previously that the resistant characteristics of these strains are spread primarily by the …


The Critical Need For Mental Health Education To Be Mandated In New Mexico's Public Schools, Bonnie L. Murphy Nov 2018

The Critical Need For Mental Health Education To Be Mandated In New Mexico's Public Schools, Bonnie L. Murphy

Shared Knowledge Conference

Based on a review of research and best practices in mental health awareness and skills, this inquiry project argues for state legislative policies that would require mental health awareness and skills in the K-12 curriculum. Mental health affects individual accomplishments in every stage of people’s lives beginning in early childhood and throughout the life cycle. Prevention and treatment of mental illness plays a key role in the ability of an individual to cope with loss and develop resiliency and perseverance in challenging times and to make better decisions that improve the individual’s life and the lives of those around them. …