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Full-Text Articles in Life Sciences
The Effect Of The Dietary Polyphenols Quercetin And Resveratrol On Wound Healing In Bovine Corneal Endothelial Cells In Vitro, Amie E. Abell
The Effect Of The Dietary Polyphenols Quercetin And Resveratrol On Wound Healing In Bovine Corneal Endothelial Cells In Vitro, Amie E. Abell
Mahurin Honors College Capstone Experience/Thesis Projects
The corneal endothelium is a monolayer of cells critical in maintaining a transparent cornea. Its cells are amitotic during adulthood; thus, tissue repair depends primarily on cellular growth and migration. Enhancing repair may improve recovery time from surgical procedures and corneal diseases that damage the endothelium. Inflammation resulting from endothelial injury is characterized by increased concentrations of free radicals in the endothelium and aqueous humor, slowing wound repair. The antioxidant vitamins and antioxidant enzymes neutralize free radicals, but damage can occur when this system is overwhelmed by high concentrations of reactive oxygen species. This project develops an in vitro model …
Zebrafish Cone Contributions And Erg Waveforms As Impacted By Cnqx, Margaret G. Au
Zebrafish Cone Contributions And Erg Waveforms As Impacted By Cnqx, Margaret G. Au
Mahurin Honors College Capstone Experience/Thesis Projects
The effect of the glutamate antagonist CNQX (6-cyano-7-nitroquinoxaline-2,3dione) on Off-bipolar cells in the zebrafish (Dania reria) was examined. CNQX has suppressed the d-wave component of electroretinogram (ERG) in other species. Here, adult zebrafish received an injection ofCNQX or saline solution. They were then presented 200 ms stimuli at 17 wavelengths and several irradiances. Spectral sensitivity was calculated from the b-wave components ofthe ERG responses. Retinal injection of CNQX impacted the a-, b-, and d-waves ofthe ERG, especially at longer wavelengths. Significant differences in the spectral sensitivity functions of the CNQX and saline groups were found at 460 nm and 540 …