Open Access. Powered by Scholars. Published by Universities.®

Life Sciences Commons

Open Access. Powered by Scholars. Published by Universities.®

Honors Theses

2019

Discipline
Institution
Keyword
Publication Type

Articles 151 - 154 of 154

Full-Text Articles in Life Sciences

Assessing The Effects Of Antioxidants On Oxidative Stress In Triple-Negative Breast Cancer Cells Via Protein Carbonylation, Dalton Sheffield Jan 2019

Assessing The Effects Of Antioxidants On Oxidative Stress In Triple-Negative Breast Cancer Cells Via Protein Carbonylation, Dalton Sheffield

Honors Theses

Breast cancer is a highly complex, heterogeneous disease, and potential effective treatment options are being continuously researched in order to provide a method of halting cancer growth and metastasis. One area in particular involves alleviating oxidative stress within cancer cells. Oxidative stress is generally defined as an imbalance between oxidant and antioxidant species in favor of the oxidants. Cancer cells use this oxidative stress to initiate carcinogenesis in cells through different mechanisms, and protein carbonylation is a primary biomarker used to quantify oxidative stress levels. Antioxidant compounds are those used to alleviate oxidative stress within cells. Here breast cancer cells …


Carbon Dioxide Reduction Using Redox-Active Macrocyclic Catalysts, Dawson Kendall Buettner Jan 2019

Carbon Dioxide Reduction Using Redox-Active Macrocyclic Catalysts, Dawson Kendall Buettner

Honors Theses

The current energy crisis experienced by society today is in desperate need of a solution. Through carbon dioxide (CO2) reduction, we can reduce the amount of greenhouse gas that is warming our planet as well as create a source of renewable energy. Significant challenges currently inhibit the reduction of CO2 to more desirable products. Current limitations can be addressed through the design and synthesis of more efficient catalysts that are selective, durable, and operate close to the target thermodynamic potential of CO2 reduction. In this work, three redox-active macrocyclic ligands have been synthesized and studied for the development of potential …


Compositional Differences In Bacterial Communities In Fresh And Saltwater Wetlands Of The Gulf Coast, Mary Grace Bass Jan 2019

Compositional Differences In Bacterial Communities In Fresh And Saltwater Wetlands Of The Gulf Coast, Mary Grace Bass

Honors Theses

Wetlands are important reservoirs for biodiversity and ecosystem services such as nutrient cycling. However, the anthropogenic stressors of sea-level rise and eutrophication threaten these habitats. In this study, I examined the bacterial communities at six locations along the US Gulf Coast between Louisiana and Florida, focusing on how these communities were affected by salinity, depth, and site location. At each of six locations, five 30cm-deep soil cores were taken from a tidal fresh marsh and either a tidal brackish marsh or tidal saltmarsh. Bacterial DNA was extracted from both the surface layer and the root layer of each soil core. …


Protein Templated Silver Nanoclusters, Greyson Keel Jan 2019

Protein Templated Silver Nanoclusters, Greyson Keel

Honors Theses

Nanoclusters are smaller than their nanoparticle counterparts and have unique properties. Most research has been done on gold nanoclusters, but silver nanoclusters are said to be more robust. During the process of trying to create nanoclusters, several methods in the procedure were changed when gathering data: determining a successful silver concentration, working with the correct buffer, mixing gold and silver metals together, observing the effects of pH, and finding a good reducing agent. After experimenting with those changes, a successful protocol was adapted and modified from literature (Journal of Materials Chemistry, 2011, 21, 11205-11212) to produce the protein-templated Ag clusters. …