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Full-Text Articles in Life Sciences

Festival Of Research Abstracts, 2024, College Of Science And Mathematics, Wright State University Jan 2024

Festival Of Research Abstracts, 2024, College Of Science And Mathematics, Wright State University

Festival of Research

The collection of abstracts accepted for the 2024 Festival of Research hosted by the Wright State University College of Science and Mathematics.


Exploration Of C9or72c9-500 Sk2, Sk3 Channel Expression, Teresa L. Garrett Mar 2023

Exploration Of C9or72c9-500 Sk2, Sk3 Channel Expression, Teresa L. Garrett

Festival of Research

ALS (also known as Lou Gehrig's Disease) is a neurodegenerative disease that weakens muscles and impacts physical function. The C9 Gene is responsible for creating proteins that help neurons send and receive signals across the synapse. Small Conductance calcium activated potassium channels (SK channels) affect the hyperpolarization phase of an action potential. Hypothesis: SK2 and SK3 clusters of C9 positive cells should decrease in size and intensity when exposed to a disease state compared to C9 negative controls.


The Effects Of Chronic Hypercarbia On Morphological And Ventilatory Development In Crayfish, Cassandra Poeppelman, Josh Hivner, Lynn K. Hartzler Mar 2023

The Effects Of Chronic Hypercarbia On Morphological And Ventilatory Development In Crayfish, Cassandra Poeppelman, Josh Hivner, Lynn K. Hartzler

Festival of Research

Instances of abnormally high CO2 levels are becoming increasingly common in freshwater ecosystems undergoing eutrophication. Chronic hypercarbia (long-term elevation of the partial pressure of carbon dioxide (Pco2)) is pervasive in these eutrophic ecosystems. Elevated Pco2 increases the ventilation and metabolism of some tadpoles and aquatic frogs and hinders their morphological development23. We expect that chronic hypercarbia will affect most aquatic organisms in the same way, but it remains to be verified that chronic hypercarbic conditions also alter aquatic organisms similarly to intermittent and acute hypercarbic challenges.


The Influence Of Als-Associated Matr3 Toxicity On Cell Size In The Yeast Model, Rahul Shah, Fawaz Ghouse, Widad El-Zein, Quan Zhong, Shulin Ju Mar 2023

The Influence Of Als-Associated Matr3 Toxicity On Cell Size In The Yeast Model, Rahul Shah, Fawaz Ghouse, Widad El-Zein, Quan Zhong, Shulin Ju

Festival of Research

Amyotrophic Lateral Sclerosis (ALS) is a fatal neurodegenerative disease1. The pathology of ALS is described as the progressive degeneration of motor neurons that initially leads to atrophy of the voluntary muscles followed by the involuntary muscles1,2. Ultimately, the cause of death is pulmonary distress due to loss of function of the diaphragm2. Life expectancy after diagnosis is usually one year, and there are currently no cures or effective treatments for this fatal disease3. Approximately 90% of all ALS cases are sporadic meaning that the disease is developed randomly, while around 10% of the cases are familial meaning that the disease …


Festival Of Research Abstracts, 2023, College Of Science And Mathematics, Wright State University Jan 2023

Festival Of Research Abstracts, 2023, College Of Science And Mathematics, Wright State University

Festival of Research

The collection of abstracts accepted for the 2023 Festival of Research hosted by the Wright State University College of Science and Mathematics.