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Articles 1 - 10 of 10
Full-Text Articles in Life Sciences
Introducing Comprehensive Sexuality Education And Hiv Prevention And Treatment Methods Through Pop-Up Clinics To Secondary School Girls In Kwazulu-Natal, South Africa, Eliza I. Tobin, Joaquin Carlos Pinga, Caitlyn Stanya
Introducing Comprehensive Sexuality Education And Hiv Prevention And Treatment Methods Through Pop-Up Clinics To Secondary School Girls In Kwazulu-Natal, South Africa, Eliza I. Tobin, Joaquin Carlos Pinga, Caitlyn Stanya
Capstone Showcase
Human immunodeficiency virus (HIV) is a retrovirus that attacks the immune system leading to people living with HIV (PLHIV) immunodeficient and more susceptible to other infections or diseases (UNAIDS, 2023b). This can lead to acquired immunodeficiency syndrome (AIDS) within 8-10 years of infection (UNAIDS, 2023b). HIV does not always present symptoms, making it hard for people to identify their HIV status without proper screening. The lack of awareness around a person’s status has led HIV to spread worldwide. In addition to the worldwide spread of HIV, there is no cure for the disease, however, antiretroviral therapy (ART) is mainly used …
Effects Of Duckweed On Mosquito Oviposition And Larval Survivorship, Alyssa Gushka
Effects Of Duckweed On Mosquito Oviposition And Larval Survivorship, Alyssa Gushka
Capstone Showcase
Invasive species are those non-natives to habitat and that negatively impact the environment or human health problems. Invasive mosquitoes threaten the environment and humans, as they transmit 17% of infectious diseases including malaria, West Nile virus and yellow fever. Aedes japonicas and Aedes albopictus are invasive mosquitoes that often deposit eggs in artificial containers. Chemical pesticides, such as Bacillus thuringiensis israelensis (BTI), utilizes endospores to release toxins into the larvae. However, BTI creates negative consequences for the environment and other species. Many plants are being examined to see if they can act as natural pesticides. Duckweeds are native to North …
Vitamin D Enhanced Vitamin D Receptor (Vdr) Inhibition Of Nlrp3 Inflammasome Activation Can Attenuate The Development Of Autoimmune Thyroiditis, Alexzon Mandac
Vitamin D Enhanced Vitamin D Receptor (Vdr) Inhibition Of Nlrp3 Inflammasome Activation Can Attenuate The Development Of Autoimmune Thyroiditis, Alexzon Mandac
Capstone Showcase
Autoimmune Thyroiditis (AIT) is a prevalent autoimmune disease affecting approximately 2% of the population. Characterized by the gradual loss of thyroid function through an autoimmune attack on the thyroid gland, the disease manifests symptoms that negatively affect one’s quality of life. The mechanisms behind the disease’s pathophysiology are not fully understood; however, researchers are examining the involvement of the NLRP3 inflammasome in the disease. This thesis will address the question of whether Vitamin D can act as an inhibitor of the NLRP3 inflammasome and attenuate the progression of AIT in mouse model. Current investigations explore the effects of NLRP3 inhibition …
Effects Of Bacillus Thuringiensis Israelensis (Bti) And Mosquito Larvae On Invasive Mosquito Egg-Laying Behavior, Zachary Runkle
Effects Of Bacillus Thuringiensis Israelensis (Bti) And Mosquito Larvae On Invasive Mosquito Egg-Laying Behavior, Zachary Runkle
Capstone Showcase
Invasive Aedes mosquitoes, including Asian tiger mosquitoes (Aedes albopictus) and Asian bush mosquitoes (Aedes japonicus), oviposit eggs in natural and artificial sites containing stagnant water. Aedes species exhibit versatility in novel ecological environments, including flexibility in oviposition site selection and overall habitat conditions, demonstrating their continued pertinence in human society. I examined the effects of the biopesticide BTI and Aedes larvae on oviposition habitat selection in Aedes albopictus and Aedes japonicus mosquitoes by observing the number of eggs oviposited. A total of 6552 and 1362 eggs were collected in experiments one and two, respectively. Females consistently …
Effects Of Environmental Warming On Clarias Gariepinus Growth And Physiology, Dean Cahill
Effects Of Environmental Warming On Clarias Gariepinus Growth And Physiology, Dean Cahill
Capstone Showcase
Fresh water makes up about 0.8% of the Earth’s surface and is home to six percent of its species. Environmental warming is projected to have a significant effect on freshwater systems as the century progresses. They are susceptible to irreversible damage because fresh water availability and temperature is dependent of climate. The Clarias gariepinus, or the African Catfish, is popular among aquaculture in Africa and Asia because of its rapid growth, quick reproduction, and hardiness. The goal of my thesis was to examine the effect of environmental warming and elevated temperatures on the growth and physiology of Clarias gariepinus populations …
How The Amino Acid L-Serine Provides Neuroprotection Against L-Bmaa Induced Alzheimer’S Disease, Joseph Cimino
How The Amino Acid L-Serine Provides Neuroprotection Against L-Bmaa Induced Alzheimer’S Disease, Joseph Cimino
Capstone Showcase
More than 6 million people in America are living with Alzheimer’s Disease (AD) and there are currently no cures or treatments. It is time to move on from the ꞵ-amyloid hypothesis and broaden AD research. New research is suggesting that dietary exposure to a cyanobacterial toxin known as L-BMAA is causing neurodegenerative diseases such as AD, Amyotrophic lateral sclerosis (ALS), and Parkinson’s Disease. L-BMAA is misincorporated during protein folding, in place of the proper amino acid, L-Serine. It has been shown that the naturally occurring amino acid, L-Serine, can provide neuroprotection against L-BMAA, but the mechanism by which L-Serine infers …
Restoration Through Regeneration: An Analysis Of Agriculture In The United States, Rebecca Norine Graham
Restoration Through Regeneration: An Analysis Of Agriculture In The United States, Rebecca Norine Graham
Capstone Showcase
The industrialization of agriculture in the mid-twentieth century has revolutionized global food systems, with enough food produced annually to sustain 10 billion people on a planet of only 7.8 billion people. Such a high-yielding agricultural system comes at a great cost to the Earth’s ecosystem, as industrialized farming has taken on factory-like production methods. Particularly harmful is the livestock sector, with ruminating animals such as cattle contributing to rising global temperatures and environmental degradation. The environmental destruction caused by industrialized animal agriculture can be halted and ultimately reversed through regenerative agriculture. Regenerative agriculture is a restorative farming practice that promotes …
Opioid Use Disorder: The Timeline For Medication Assisted Therapy, Alexander Cristofori
Opioid Use Disorder: The Timeline For Medication Assisted Therapy, Alexander Cristofori
Capstone Showcase
Opioid Use Disorder is patterns of opioid use leading to withdrawal, giving up important life events in order to use opioids, and excessive time spent using opioids, to name a few diagnostic criteria. The clinical progression of the disorder involves periods of acute exacerbation and remission that are cyclic in nature. Treatment is most effective when it includes both pharmacological and psychosocial modalities, referred to as medication assisted therapy (MAT). Three drugs used commonly in MAT-based treatment for OUD from oldest to newest include Methadone, Buprenorphine-naloxone, and Naltrexone. Treatment program models that prioritize total abstinence from the addictive substance attached …
The Efficacy Of Ketamine In Adult Patients With Obsessive Compulsive Disorder With Symptoms Refractory To Standard Of Care Treatment., Brooke Thornton
The Efficacy Of Ketamine In Adult Patients With Obsessive Compulsive Disorder With Symptoms Refractory To Standard Of Care Treatment., Brooke Thornton
Capstone Showcase
First line pharmacologic treatments for adult patients with Obsessive Compulsive Disorder (OCD) involve selective serotonin/norepinephrine reuptake inhibitors (SSRI/SNRIs). These drug classes often fail to deliver timely relief of symptoms as well as maintain longevity of symptom recurrence. This research analyzed the use of ketamine in adult patients suffering with OCD for the purposes of more efficacious management of symptoms. Although ketamine demonstrated a timelier relief of symptoms in some small clinical studies, its effects were ultimately unable to be sustained long term. Additionally, a wide range of adverse effects including dissociation, and rebound symptoms were observed. As a result, large …
Modeling Gene Expression With Differential Equations, Madison Kuduk
Modeling Gene Expression With Differential Equations, Madison Kuduk
Capstone Showcase
Gene expression is the process by which the information stored in DNA is convertedinto a functional gene product, such as protein. The two main functions that makeup the process of gene expression are transcription and translation. Transcriptionand translation are controlled by the number of mRNA and protein in the cell. Geneexpression can be represented as a system of first order differential equations for the rateof change of mRNA and proteins. These equations involve transcription, translation,degradation and feedback loops. In this paper, I investigate a system of first orderdifferential equations to model gene expression proposed by Hunt, Laplace, Miller andPham in …