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Articles 1 - 30 of 1011
Full-Text Articles in Life Sciences
The Value Of Support: Stem Intervention Programs Impact Student Persistence And Belonging., Erin E. Shortlidge, Mackenzie J. Gray, Suzanne Estes, Emma C. Goodwin
The Value Of Support: Stem Intervention Programs Impact Student Persistence And Belonging., Erin E. Shortlidge, Mackenzie J. Gray, Suzanne Estes, Emma C. Goodwin
Biology Faculty Publications and Presentations
In response to unwaveringly high attrition from STEM pathways, STEM Intervention Programs (SIPs) support STEM students in effort to increase retention. Using mixed methods (survey and focus groups), we studied students at one university who were either supported or unsupported by SIPs to understand how students may differ in experiences believed to contribute to STEM persistence. We evaluated: sense of belonging, scientific self-efficacy, scientific community values, scientific identity, and STEM involvement. The enrollment status of students two and a half years postsurvey was also tracked. SIP students reported significantly higher science identity and sense of belonging and were more involved …
Oil Identification Of Harp Seal And Other Select Marine Mammals, Meghan Pinedo, Deborah A. Duffield, Dalin N. D’Alessandro, Erin R. Price, Edgard O. Espinoza
Oil Identification Of Harp Seal And Other Select Marine Mammals, Meghan Pinedo, Deborah A. Duffield, Dalin N. D’Alessandro, Erin R. Price, Edgard O. Espinoza
Biology Faculty Publications and Presentations
Because of the rich omega-3 fatty acids content, harp seal (Pagophilus groenlandicus) oil is a popular supplement that is packaged as pills in Canada and sold for medicinal purposes, although this practice is banned in the United States. Due to US regulations, it is important to be able to distinguish between fish oil and seal oil, but the taxonomic determination of oils provenance has been a difficult problem to solve. In this study, Direct Analysis in Real Time time-of-flight mass spectrometry (DART TOFMS) was used to analyze the chemotypes of blubber samples collected from seven species of …
Autism Risk Gene Cul3 Alters Neuronal Morphology Via Caspase-3 Activity In Mouse Hippocampal Neurons, Qiang-Qiang Xia, Anju Singh, Jing Wang, Zhong Xin Xuan, Jeffrey D. Singer, Craig M. Powell
Autism Risk Gene Cul3 Alters Neuronal Morphology Via Caspase-3 Activity In Mouse Hippocampal Neurons, Qiang-Qiang Xia, Anju Singh, Jing Wang, Zhong Xin Xuan, Jeffrey D. Singer, Craig M. Powell
Biology Faculty Publications and Presentations
Autism Spectrum Disorders (ASDs) are neurodevelopmental disorders (NDDs) in which children display differences in social interaction/communication and repetitive stereotyped behaviors along with variable associated features. Cul3, a gene linked to ASD, encodes CUL3 (CULLIN-3), a protein that serves as a key component of a ubiquitin ligase complex with unclear function in neurons. Cul3 homozygous deletion in mice is embryonic lethal; thus, we examine the role of Cul3 deletion in early synapse development and neuronal morphology in hippocampal primary neuronal cultures. Homozygous deletion of Cul3 significantly decreased dendritic complexity and dendritic length, as well as axon formation. Synaptic spine density significantly …
Demography With Drones: Detecting Growth And Survival Of Shrubs With Unoccupied Aerial Systems, Peter J. Olsoy, Andrii Zaiats, Donna M. Delparte, Matthew J. Germino, Bryce A. Richardson, Anna V. Roser, Jennifer S. Forbey, Megan E. Cattau, T. Trevor Caughlin
Demography With Drones: Detecting Growth And Survival Of Shrubs With Unoccupied Aerial Systems, Peter J. Olsoy, Andrii Zaiats, Donna M. Delparte, Matthew J. Germino, Bryce A. Richardson, Anna V. Roser, Jennifer S. Forbey, Megan E. Cattau, T. Trevor Caughlin
Biology Faculty Publications and Presentations
Large-scale disturbances, such as megafires, motivate restoration at equally large extents. Measuring the survival and growth of individual plants plays a key role in current efforts to monitor restoration success. However, the scale of modern restoration (e.g., >10,000 ha) challenges measurements of demographic rates with field data. In this study, we demonstrate how unoccupied aerial system (UAS) flights can provide an efficient solution to the tradeoff of precision and spatial extent in detecting demographic rates from the air. We flew two, sequential UAS flights at two sagebrush (Artemisia tridentata) common gardens to measure the survival and growth of …
Season Of Grazing Interacts With Soil Texture, Selecting For Associations Of Biocrust Morphogroups, Lea A. Condon, Roger Rosentreter, Kari E. Veblen, Peter S. Coates
Season Of Grazing Interacts With Soil Texture, Selecting For Associations Of Biocrust Morphogroups, Lea A. Condon, Roger Rosentreter, Kari E. Veblen, Peter S. Coates
Biology Faculty Publications and Presentations
Livestock grazing, a widespread land use in semi-arid systems, is often placed in opposition to the perpetuation of biological soil crusts (“biocrusts”: lichens, mosses, and algal crusts including cyanobacteria) that live on the soil surface and provide ecosystem functions. The composition of biocrusts and vascular plants varies with climate, soils, and disturbance. In general, ruderal mosses and light algal crusts make up greater proportions of biocrusts in the presence of disturbance, although morphogroups of biocrusts respond differently to various disturbances. It is unknown if there are scenarios under which grazing can occur and ruderal components of biocrust could be maintained. …
Effective Dispersal Patterns In Prairie Plant Species Across Human-Modified Landscapes., Elizabeth C. Hendrickson, Mitchell B. Cruzan
Effective Dispersal Patterns In Prairie Plant Species Across Human-Modified Landscapes., Elizabeth C. Hendrickson, Mitchell B. Cruzan
Biology Faculty Publications and Presentations
Effective dispersal among plant populations is dependent on vector behaviour, landscape features and availability of adequate habitats. To capture landscape feature effects on dispersal, studies must be conducted at scales reflecting single-generation dispersal events (mesoscale). Many studies are conducted at large scales where genetic differentiation is due to dispersal occurring over multiple generations, making it difficult to interpret the effects of specific landscape features on vector behaviour. Genetic structure at the mesoscale may be determined by ecological and evolutionary processes, such as the consequences of vector behaviour on patterns of gene flow. We used chloroplast haplotypes and nuclear genome SNP …
Continuous Mowing Differentially Affects Floral Defenses In The Noxious And Invasive Weed Solanum Elaeagnifolium In Its Native Range, Alejandro Vasquez, Alexa Alaniz, Robert K. Dearth, Rupesh R. Kariyat
Continuous Mowing Differentially Affects Floral Defenses In The Noxious And Invasive Weed Solanum Elaeagnifolium In Its Native Range, Alejandro Vasquez, Alexa Alaniz, Robert K. Dearth, Rupesh R. Kariyat
Biology Faculty Publications and Presentations
In weeds, disturbance has been found to affect life history traits and mediate trophic interactions. In urban landscapes, mowing is an important disturbance, and we previously showed that continuous mowing leads to enhanced fitness and defense traits in Solanum elaeagnifolium, Silverleaf Nightshade (SLN). However, most studies have been focused on foliar defenses, ignoring floral defenses. In this study we examined whether continuous mowing affected floral defenses in SLN using mowed and unmowed populations in South Texas, their native range. We found flowers of mowed SLN plants larger but lighter than unmowed plants. Additionally, flowers on plants that were mowed …
Effects Of Wind Turbine Noise On Songbird Behavior During Nonbreeding Season, Yael Lehnardt, Jesse R. Barber, Oded Berger-Tal
Effects Of Wind Turbine Noise On Songbird Behavior During Nonbreeding Season, Yael Lehnardt, Jesse R. Barber, Oded Berger-Tal
Biology Faculty Publications and Presentations
Anthropogenic noise is one of the fastest growing, globally widespread pollutants, affecting countless species worldwide. Despite accumulating evidence of the negative impacts of wind turbines on wildlife, little is known about how the noise they generate affects ecological systems. Songbirds may be susceptible to noise pollution due to their reliance on vocal communication and thus, in this field study, we examined how songbirds are affected by wind turbine noise. We broadcasted noise produced by one wind turbine in a migratory stopover site during the nonbreeding season. Throughout the study, we repeatedly monitored the acoustic environment and songbird community before, during, …
Rhizobia-Legume Symbiosis Mediates Direct And Indirect Interactions Between Plants, Herbivores And Their Parasitoids, Carlos Bustos-Segura, Adrienne L. Godschalx, Lucas Malacari, Sergio Rasmann, Fanny Deiss, Daniel Ballhorn, Betty Benrey
Rhizobia-Legume Symbiosis Mediates Direct And Indirect Interactions Between Plants, Herbivores And Their Parasitoids, Carlos Bustos-Segura, Adrienne L. Godschalx, Lucas Malacari, Sergio Rasmann, Fanny Deiss, Daniel Ballhorn, Betty Benrey
Biology Faculty Publications and Presentations
Microorganisms associated with plant roots significantly impact the quality and quantity of plant defences. However, the bottom-up effects of soil microbes on the aboveground multitrophic interactions remain largely under studied. To address this gap, we investigated the chemically- mediated effects of nitrogen-fixing rhizobia on legume-herbivore-parasitoid multitrophic interactions. To address this, we initially examined the cascading effects of the rhizobia bean association on herbivore caterpillars, their parasitoids, and subsequently investigated how rhizobia influence on plant volatiles and extrafloral nectar. Our goal was to understand how these plant- mediated effects can affect parasitoids. Lima bean plants (Phaseoulus lunatus) inoculated with rhizobia exhibited …
Proteomic Dataset For Decellularization Of Porcine Auricular Cartilage, Roxanne N. Stone, Xinzhu Pu, Julia Thom Oxford
Proteomic Dataset For Decellularization Of Porcine Auricular Cartilage, Roxanne N. Stone, Xinzhu Pu, Julia Thom Oxford
Biology Faculty Publications and Presentations
Objectives Osteoarthritis (OA) is a major concern in the United States and worldwide. Development and validation of robust decellularization techniques is critical in generating suitable bioscaffolds for future OA treatment options.
Data descriptions In the present study, proteins from porcine auricular cartilage before and after decellularization were extracted, digested, and identified using liquid chromatography-tandem mass spectrometry (LC-MS/MS). The data represents protein profiles of both non-decellularized and decellularized porcine auricular cartilage. This data is intended to be useful to scientists who are interesting in generating biomaterials for potential relevant clinical applications using decellularized cartilage tissue.
Overlapping Extractive Land Use Rights Increases Deforestation And Forest Degradation In Managed Natural Production Forests, Bingcai Liu, Anand Roopsind, Brent Sohngen
Overlapping Extractive Land Use Rights Increases Deforestation And Forest Degradation In Managed Natural Production Forests, Bingcai Liu, Anand Roopsind, Brent Sohngen
Biology Faculty Publications and Presentations
Guyana manages an estimated 5.3 million hectares of old-growth tropical forests, 29% of its total forest area, for timber extraction. Individuals and companies can apply for time-limited leases that allocate access, management, and extraction rights for timber through a concession system. In many tropical regions, including Guyana, a lack of integrated land use planning often leads to overlapping extractive and forest use rights for logging and mining. Overlapping land rights in turn create uncertainty and limit investments toward sustainable forest management, affecting deforestation and forest degradation rates. In this study, we use matched fixed-effect and difference-in-differences panel data models to …
The Role Of Nad+ And Nad+-Boosting Therapies In Inflammatory Response By Il-13, Anton D. Pugel, Alyssa M. Schoenfeld, Sara Z. Alsaifi, Jocelyn R. Holmes, Brad E. Morrison
The Role Of Nad+ And Nad+-Boosting Therapies In Inflammatory Response By Il-13, Anton D. Pugel, Alyssa M. Schoenfeld, Sara Z. Alsaifi, Jocelyn R. Holmes, Brad E. Morrison
Biology Faculty Publications and Presentations
The essential role of nicotinamide adenine dinucleotide+ (NAD+) in redox reactions during oxidative respiration is well known, yet the coenzyme and regulator functions of NAD+ in diverse and important processes are still being discovered. Maintaining NAD+ levels through diet is essential for health. In fact, the United States requires supplementation of the NAD+ precursor niacin into the food chain for these reasons. A large body of research also indicates that elevating NAD+ levels is beneficial for numerous conditions, including cancer, cardiovascular health, inflammatory response, and longevity. Consequently, strategies have been created to elevate …
Ubiquitous Filter Feeders Shape Open Ocean Microbial Community Structure And Function, Anne W. Thompson, Györgyi Nyerges, Kylee M. Brevick, Kelly Sutherland
Ubiquitous Filter Feeders Shape Open Ocean Microbial Community Structure And Function, Anne W. Thompson, Györgyi Nyerges, Kylee M. Brevick, Kelly Sutherland
Biology Faculty Publications and Presentations
The mechanism of mortality plays a large role in how microorganisms in the open ocean contribute to global energy and nutrient cycling. Salps are ubiquitous pelagic tunicates that are a well-known mortality source for large phototrophic microorganisms in coastal and high-latitude systems, but their impact on the immense populations of smaller prokaryotes in the tropical and subtropical open ocean gyres is not well quantified. We used robustly quantitative techniques to measure salp clearance and enrichment of specific microbial functional groups in the North Pacific Subtropical Gyre, one of the largest ecosystems on Earth. We discovered that salps are a previously …
Applied Soft Classes And Fuzzy Confusion In A Patchwork Semi-Arid Ecosystem: Stitching Together Classification Techniques To Preserve Ecologically-Meaningful Information, Josh Enterkine, T. Trevor Caughlin, Hamid Dashti, Nancy F. Glenn
Applied Soft Classes And Fuzzy Confusion In A Patchwork Semi-Arid Ecosystem: Stitching Together Classification Techniques To Preserve Ecologically-Meaningful Information, Josh Enterkine, T. Trevor Caughlin, Hamid Dashti, Nancy F. Glenn
Biology Faculty Publications and Presentations
Dryland ecosystems have complex vegetation communities, including subtle transitions between communities and heterogeneous coverage of key functional groups. This complexity challenges the capacity of remote sensing to represent land cover in a meaningful way. Many remote sensing methods to map vegetation in drylands simplify fractional cover into a small number of functional groups that may overlook key ecological communities. Here, we investigate a remote sensing process that further advances our understanding of the link between remote sensing and ecologic community types in drylands. We propose a method using k-means clustering to establish soft classes of vegetation cover communities from detailed …
9s1r Nullomer Peptide Induces Mitochondrial Pathology, Metabolic Suppression, And Enhanced Immune Cell Infiltration, In Triple-Negative Breast Cancer Mouse Model, Nilufar Ali, Cody Wolf, Swarna Kanchan, Shivakumar R. Veerabhadraiah, Laura Bond, Matthew W. Turner, Cheryl L. Jorcyk, Greg Hampikian
9s1r Nullomer Peptide Induces Mitochondrial Pathology, Metabolic Suppression, And Enhanced Immune Cell Infiltration, In Triple-Negative Breast Cancer Mouse Model, Nilufar Ali, Cody Wolf, Swarna Kanchan, Shivakumar R. Veerabhadraiah, Laura Bond, Matthew W. Turner, Cheryl L. Jorcyk, Greg Hampikian
Biology Faculty Publications and Presentations
Nullomers are the shortest strings of absent amino acid (aa) sequences in a species or group of species. Primes are those nullomers that have not been detected in the genome of any species. 9S1R is a 5-aa peptide prime sequence attached to 5-arginine aa, used to treat triple negative breast cancer (TNBC) in an in vivo mouse model. This unique peptide, administered with a trehalose carrier (9S1R-NulloPT), offers enhanced solubility and exhibits distinct anti-cancer effects against TNBC. In our study, we investigated the effect of 9S1R-NulloPT on tumor growth, metabolism, metastatic burden, tumor immune-microenvironment (TME), and transcriptome of aggressive mouse …
Leveraging High Resolution Classifications And Random Forests For Hindcasting Decades Of Mesic Ecosystem Dynamics In The Landsat Time Series, N. E. Kolarik, N. Shrestha, T. Caughlin, J. S. Brandt
Leveraging High Resolution Classifications And Random Forests For Hindcasting Decades Of Mesic Ecosystem Dynamics In The Landsat Time Series, N. E. Kolarik, N. Shrestha, T. Caughlin, J. S. Brandt
Biology Faculty Publications and Presentations
Mesic ecosystems are fundamental to conservation efforts in semi-arid systems, but are threatened by climate change and development. Newer earth observation datasets, including Sentinel-1 and −2, provide opportunities to monitor mesic ecosystems at meaningful spatial scales, but are insufficient for measuring decadal-scale changes. Conversely, the Landsat time series has decades of data, but images are spatially coarse relative to many of the mesic ecosystem areas that sustain dryland systems, resulting in classifications with mixed pixels inadequate for effective monitoring. We developed a workflow that uses 10-m classifications produced from fusion of the Sentinel-1 and −2 time series (2017–2020) to estimate …
Low Spatial Habitat Overlap Of Herbivores In The High Arctic Tundra, Virve Ravolainen, Ingrid M. G. Paulsen, Isabell Eischeid, Jennifer Sorensen Forbey, Eva Fuglei, Tomáš Hájek, Brage B. Hansen, Leif Egil Loe, Petr Macek, Jesper Madsen, Eeva M. Soininen, James D. M. Speed, Audun Stien, Hans Tømmervik, Åshild Ønvik Pedersen
Low Spatial Habitat Overlap Of Herbivores In The High Arctic Tundra, Virve Ravolainen, Ingrid M. G. Paulsen, Isabell Eischeid, Jennifer Sorensen Forbey, Eva Fuglei, Tomáš Hájek, Brage B. Hansen, Leif Egil Loe, Petr Macek, Jesper Madsen, Eeva M. Soininen, James D. M. Speed, Audun Stien, Hans Tømmervik, Åshild Ønvik Pedersen
Biology Faculty Publications and Presentations
Herbivores play a crucial role in shaping tundra ecosystems through their effects on vegetation, nutrient cycling, and soil abiotic factors. Understanding their habitat use, co-occurrence, and overlap is therefore essential for informing ecosystem-based management and conservation. In the High Arctic, only a marginal proportion of the land area is vegetated, and climate change is impacting herbivore population sizes and their habitats. In this study, we assessed the spatial habitat overlap of a vertebrate herbivore community based on: 1) regional predictive summer habitat suitability models for the resident Svalbard reindeer (Rangifer tarandus platyrhynchus), resident Svalbard rock ptarmigan (Lagopus …
Tarantula Toxin Transcripts And Toxin Structure Prediction By Alphafold, Christine Vega, Rebekkah Sepulveda, Ying Jia
Tarantula Toxin Transcripts And Toxin Structure Prediction By Alphafold, Christine Vega, Rebekkah Sepulveda, Ying Jia
Biology Faculty Publications and Presentations
Tarantula venom predominantly comprises peptides and small proteins (venom toxins). To explore this further, we generated a combined gland cDNA library from five different tarantula species. Subsequently we randomly sequenced 752 clones, which led to the identification of sixteen distinct toxin groups, including one novel group. Each group consists of a minimum of three identical sequences. A comprehensive analysis of these toxin groups was carried out, and we simulated the 3D structures of certain predicted toxins. These transcripts can be used to the production of venom toxins through recombinant techniques, offering promising applications in various biomedical applications.
Genomic Surveillance Of Sars-Cov-2 Sequence Variants At Universities In Southwest Idaho, Jennifer R. Chase, Laura Bond, Daniel J. Vail, Milan Sengthep, Adriana Rodriguez, Joe Christianson, Stephanie F. Hudon, Julia Thom Oxford
Genomic Surveillance Of Sars-Cov-2 Sequence Variants At Universities In Southwest Idaho, Jennifer R. Chase, Laura Bond, Daniel J. Vail, Milan Sengthep, Adriana Rodriguez, Joe Christianson, Stephanie F. Hudon, Julia Thom Oxford
Biology Faculty Publications and Presentations
Although the impact of the SARS-CoV-2 pandemic on major metropolitan areas is broadly reported and readily available, regions with lower populations and more remote areas in the United States are understudied. The objective of this study is to determine the progression of SARS-CoV-2 sequence variants in a frontier and remote intermountain west state among university-associated communities. This study was conducted at two intermountain west universities from 2020 to 2022. Positive SARS-CoV-2 samples were confirmed by quantitative real-time reverse transcription-polymerase chain reaction and variants were identified by the next-generation sequencing of viral genomes. Positive results were obtained for 5355 samples, representing …
A Genus In The Bacterial Phylum Aquificota Appears To Be Endemic To Aotearoa-New Zealand, Jean F. Power, Carlo R. Carere, Holly E. Welford, Daniel T. Hudson, Kevin C. Lee, John W. Moreau, Anna-Louise Reysenbach, Thijs J.G. Ettema, Multiple Additional Authors
A Genus In The Bacterial Phylum Aquificota Appears To Be Endemic To Aotearoa-New Zealand, Jean F. Power, Carlo R. Carere, Holly E. Welford, Daniel T. Hudson, Kevin C. Lee, John W. Moreau, Anna-Louise Reysenbach, Thijs J.G. Ettema, Multiple Additional Authors
Biology Faculty Publications and Presentations
Allopatric speciation has been difficult to examine among microorganisms, with prior reports of endemism restricted to sub-genus level taxa. Previous microbial community analysis via 16S rRNA gene sequencing of 925 geothermal springs from the Taupō Volcanic Zone (TVZ), Aotearoa-New Zealand, revealed widespread distribution and abundance of a single bacterial genus across 686 of these ecosystems (pH 1.2-9.6 and 17.4-99.8 °C). Here, we present evidence to suggest that this genus, Venenivibrio (phylum Aquificota), is endemic to Aotearoa-New Zealand. A specific environmental niche that increases habitat isolation was identified, with maximal read abundance of Venenivibrio occurring at pH 4-6, 50-70 °C, and …
Preparing Teaching Assistants To Facilitate Course-Based Undergraduate Research Experiences (Cures) In The Biological Sciences: A Call To Action, Erin Shortlidge, Amie M. Kern, Emma Goodwin, Jeffrey T. Olimpo
Preparing Teaching Assistants To Facilitate Course-Based Undergraduate Research Experiences (Cures) In The Biological Sciences: A Call To Action, Erin Shortlidge, Amie M. Kern, Emma Goodwin, Jeffrey T. Olimpo
Biology Faculty Publications and Presentations
Course-based undergraduate research experiences (CUREs) offer an expanding avenue to engage students in real-world scientific practices. Increasingly, CUREs are instructed by graduate teaching assistants (TAs), yet TAs may be underprepared to facilitate and face unique barriers when teaching CUREs. Consequently, unless TAs are provided professional development (PD) and resources to teach CUREs effectively, they and their students may not reap the assumed benefits of CURE instruction. Here, we describe three perspectives – that of the CURE TA, the CURE designer/facilitator, and the CURE student – that are collectively intended to inform the development of tentative components of CURE TA PD. …
Genetic And Environmental Drivers Of Migratory Behavior In Western Burrowing Owls And Implications For Conservation And Management, Kelly Barr, Christen M. Bossu, Rachel A. Bay, Eric C. Anderson, Jim Belthoff, Lynne A. Trulio, Debra Chromczak, Colleen L. Wisinski, Thomas B. Smith, Kristen C. Ruegg
Genetic And Environmental Drivers Of Migratory Behavior In Western Burrowing Owls And Implications For Conservation And Management, Kelly Barr, Christen M. Bossu, Rachel A. Bay, Eric C. Anderson, Jim Belthoff, Lynne A. Trulio, Debra Chromczak, Colleen L. Wisinski, Thomas B. Smith, Kristen C. Ruegg
Biology Faculty Publications and Presentations
Migration is driven by a combination of environmental and genetic factors, but many questions remain about those drivers. Potential interactions between genetic and environmental variants associated with different migratory phenotypes are rarely the focus of study. We pair low coverage whole genome resequencing with a de novo genome assembly to examine population structure, inbreeding, and the environmental factors associated with genetic differentiation between migratory and resident breeding phenotypes in a species of conservation concern, the western burrowing owl (Athene cunicularia hypugaea). Our analyses reveal a dichotomy in gene flow depending on whether the population is resident or migratory, …
Doxorubicin-Induced Modulation Of Tgf-Β Signaling Cascade In Mouse Fibroblasts: Insights Into Cardiotoxicity Mechanisms, Conner Patricelli, Parker Lehmann, Julia Thom Oxford, Xinzhu Pu
Doxorubicin-Induced Modulation Of Tgf-Β Signaling Cascade In Mouse Fibroblasts: Insights Into Cardiotoxicity Mechanisms, Conner Patricelli, Parker Lehmann, Julia Thom Oxford, Xinzhu Pu
Biology Faculty Publications and Presentations
Doxorubicin (DOX)-induced cardiotoxicity has been widely observed, yet the specific impact on cardiac fibroblasts is not fully understood. Additionally, the modulation of the transforming growth factor beta (TGF-β) signaling pathway by DOX remains to be fully elucidated. This study investigated DOX’s ability to modulate the expression of genes and proteins involved in the TGF-β signaling cascade in mouse fibroblasts from two sources by assessing the impact of DOX treatment on TGF-β inducible expression of pivotal genes and proteins within fibroblasts. Mouse embryonic fibroblasts (NIH3T3) and mouse primary cardiac fibroblasts (CFs) were treated with DOX in the presence of TGF-β1 to …
Germ Cell Recovery, Cryopreservation And Transplantation In The California White Sturgeon, Acipenser Transmontanus, Amie L. Romney, Danielle M. Myers, Fatima R. Martin, Tawney N. Scanlan, Stuart A. Meyers
Germ Cell Recovery, Cryopreservation And Transplantation In The California White Sturgeon, Acipenser Transmontanus, Amie L. Romney, Danielle M. Myers, Fatima R. Martin, Tawney N. Scanlan, Stuart A. Meyers
Biology Faculty Publications and Presentations
The white sturgeon (Acipenser transmontanus) is the largest freshwater fish in North America. Because of the unique life history characteristics of sturgeon, including longevity, late maturation and long spawning intervals, their aquaculture can be a significant investment of resources. As a result of habitat loss and overharvesting, natural populations of white sturgeon are threatened and there is a growing effort to improve conservation aquaculture programs. Germ cell transplantation is an innovative technology previously demonstrated in a variety of fish species to be able to produce a surrogate broodstock. The technique relies upon optimal donor germ cell recovery and transplantation into …
Drivers Of Plankton Community Structure In Intermittent And Continuous Coastal Upwelling Systems–From Microbes And Microscale In-Situ Imaging To Large Scale Patterns, Moritz Schmid, Su Sponaugle, Anne W. Thompson, Kelly T. Sutherland, Robert Cowen
Drivers Of Plankton Community Structure In Intermittent And Continuous Coastal Upwelling Systems–From Microbes And Microscale In-Situ Imaging To Large Scale Patterns, Moritz Schmid, Su Sponaugle, Anne W. Thompson, Kelly T. Sutherland, Robert Cowen
Biology Faculty Publications and Presentations
Eastern Boundary Systems support major fisheries whose early life stages depend on upwelling production. Upwelling can be highly variable at the regional scale, with substantial repercussions for new productivity and microbial loop activity. Studies that integrate the classic trophic web based on new production with the microbial loop are rare due to the range in body forms and sizes of the taxa. Underwater imaging can overcome this limitation, and with machine learning, enables fine resolution studies spanning large spatial scales. We used the In-situ Ichthyoplankton Imaging System (ISIIS) to investigate the drivers of plankton community structure in the northern California …
Big Boned: How Fat Storage And Other Adaptations Influenced Large Theropod Foraging Ecology, Cameron Pahl, Luis A. Ruedas
Big Boned: How Fat Storage And Other Adaptations Influenced Large Theropod Foraging Ecology, Cameron Pahl, Luis A. Ruedas
Biology Faculty Publications and Presentations
Dinosaur foraging ecology has been the subject of scientific interest for decades, yet much of what we understand about it remains hypothetical. We wrote an agent-based model (ABM) to simulate meat energy sources present in dinosaur environments, including carcasses of giant sauropods, along with living, huntable prey. Theropod dinosaurs modeled in this environment (specifically allosauroids, and more particularly, Allosaurus Marsh, 1877) were instantiated with heritable traits favorable to either hunting success or scavenging success. If hunter phenotypes were more reproductively successful, their traits were propagated into the population through their offspring, resulting in predator specialists. If selective pressure favored scavenger …
Foxo1 Promotes The Expression Of Canonical Wnt Target Genes In Examined Basal-Like Breast And Glioblastoma Multiforme Cancer Cells, Shania Pintor, Alma Lopez, David Flores, Brianda Lozoya, Bipul Soti, Rishi Pokhrel, Joaquin Negrete, Michael W. Persans, Robert Gilkerson, Bonnie Gunn, Megan Keniry
Foxo1 Promotes The Expression Of Canonical Wnt Target Genes In Examined Basal-Like Breast And Glioblastoma Multiforme Cancer Cells, Shania Pintor, Alma Lopez, David Flores, Brianda Lozoya, Bipul Soti, Rishi Pokhrel, Joaquin Negrete, Michael W. Persans, Robert Gilkerson, Bonnie Gunn, Megan Keniry
Biology Faculty Publications and Presentations
Basal-like breast cancer (BBC) and glioblastoma multiforme (GBM) are aggressive cancers associated with poor prognosis. BBC and GBM have stem cell-like gene expression signatures, which are in part driven by forkhead box O (FOXO) transcription factors. To gain further insight into the impact of FOXO1 in BBC, we treated BT549 cells with AS1842856 and performed RNA sequencing. AS1842856 binds to unphosphorylated FOXO1 and inhibits its ability to directly bind to DNA. Gene Set Enrichment Analysis indicated that a set of WNT pathway target genes, including lymphoid enhancer-binding factor 1 (LEF1) and transcription factor 7 (TCF7), were …
Biocrusts Indicators Of Livestock Grazing Effects On Soil Stability In Sagebrush Steppe: A Case Study From A Long-Term Experiment In The Northern Great Basin, Stella M. Copeland, Lea A. Condon, Roger Rosentreter, Jesse E. D. Miller, Maya Kahn-Abrams
Biocrusts Indicators Of Livestock Grazing Effects On Soil Stability In Sagebrush Steppe: A Case Study From A Long-Term Experiment In The Northern Great Basin, Stella M. Copeland, Lea A. Condon, Roger Rosentreter, Jesse E. D. Miller, Maya Kahn-Abrams
Biology Faculty Publications and Presentations
Biocrusts are sensitive to changes in livestock grazing intensity in arid rangelands and may be useful indicators of ecosystem functions, particularly soil properties like soil stability, which may suggest the potential for soil erosion. We compared biocrust community composition and surface soil stability in a big sagebrush (Artemisia tridentata) steppe rangeland in the northwestern Great Basin in several paired sites, with or without long-term cattle grazing exclusion, and similar soils (mostly sandy loams), climate, and vegetation composition. We found that livestock grazing was associated with both lower surface soil stability and cover of several biocrust morphogroups, especially lichens, compared with …
Background Acoustics In Terrestrial Ecology, Clinton D. Francis, Jennifer N. Phillips, Jesse R. Barber
Background Acoustics In Terrestrial Ecology, Clinton D. Francis, Jennifer N. Phillips, Jesse R. Barber
Biology Faculty Publications and Presentations
The way in which terrestrial organisms use the acoustic realm is fundamentally important and shapes behavior, populations, and communities, but how background acoustics, or noise, influence the patterns and processes in ecology is still relatively understudied. In this review, we summarize how background acoustics have traditionally been studied from the signaling perspective, discuss what is known from a receiver's perspective, and explore what is known about population- and community-level responses to noise. We suggest that there are major gaps linking animal physiology and behavior in noise to fitness; that there is a limited understanding of variation in hearing within and …
Sex And Stress Modulate Pupal Defense Response In Tobacco Hornworm, Sukhman Singh, Sakshi Watts, Ishveen Kaur, Isabella Rodriguez, Jessica Ayala, Dariela Rodriguez, Elian Martin, Rupesh R. Kariyat
Sex And Stress Modulate Pupal Defense Response In Tobacco Hornworm, Sukhman Singh, Sakshi Watts, Ishveen Kaur, Isabella Rodriguez, Jessica Ayala, Dariela Rodriguez, Elian Martin, Rupesh R. Kariyat
Biology Faculty Publications and Presentations
In insects, larval and adult defenses against predators have been well studied. However, pupal (also known as resting stage) defenses have been overlooked and not examined thoroughly. Although some pupa possess antipredator strategies such as hairs, spines, cryptic coloration, and exudation of chemicals, few studies have tested these responses and the factors affecting them. Here, we investigated the behavioral responses in tobacco hornworm Manduca sexta that pupates in soil by introducing an external stimulus using vibrations from an electric toothbrush to mimic predation. We observed that M. sexta made violent wriggling (twitching), followed by pulsating movements in response to the …