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Full-Text Articles in Life Sciences
The Hox Protein Conundrum: The “Specifics” Of Dna Binding For Hox Proteins And Their Partners, Bony De Kumar, Diane C. Darland
The Hox Protein Conundrum: The “Specifics” Of Dna Binding For Hox Proteins And Their Partners, Bony De Kumar, Diane C. Darland
Biology Faculty Publications
Homeotic genes (Hox genes) are homeodomain-transcription factors involved in conferring segmental identity along the anterior-posterior body axis. Molecular characterization of HOX protein function raises some interesting questions regarding the source of the binding specificity of the HOX proteins. How do HOX proteins regulate common and unique target specificity across space and time? This review attempts to summarize and interpret findings in this area, largely focused on results from in vitro and in vivo studies in Drosophila and mouse systems. Recent studies related to HOX protein binding specificity compel us to reconsider some of our current models for transcription factor-DNA …
Pre-Existing Microfilarial Infections Of American Robins (Passeriformes: Turdidae) And Common Grackles (Passeriformes: Icteridae) Have Limited Impact On Enhancing Dissemination Of West Nile Virus In Culex Pipiens Mosquitoes (Diptera: Culicidae), Jefferson A. Vaughan, Juanita Hinson, Elizabeth S. Andrews, Michael J. Turrell
Pre-Existing Microfilarial Infections Of American Robins (Passeriformes: Turdidae) And Common Grackles (Passeriformes: Icteridae) Have Limited Impact On Enhancing Dissemination Of West Nile Virus In Culex Pipiens Mosquitoes (Diptera: Culicidae), Jefferson A. Vaughan, Juanita Hinson, Elizabeth S. Andrews, Michael J. Turrell
Biology Faculty Publications
Microfilariae (MF) are the immature stages of filarial nematode parasites and inhabit the blood and dermis of all classes of vertebrates, except fish. Concurrent ingestion of MF and arboviruses by mosquitoes can enhance mosquito transmission of virus compared to when virus is ingested alone. Shortly after being ingested, MF penetrate the mosquito’s midgut and may introduce virus into the mosquito’s hemocoel, creating a disseminated viral infection much sooner than normal. This phenomenon is known as microfilarial enhancement. Both American Robins and Common Grackles harbor MF—that is, Eufilaria sp. and Chandlerella quiscali von Linstow (Spirurida: Onchocercidae), respectively. We compared infection and …