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Articles 61 - 61 of 61
Full-Text Articles in Life Sciences
Development And Function Of Retinal Ganglion Cell Circuits, Nai-Wen Tien
Development And Function Of Retinal Ganglion Cell Circuits, Nai-Wen Tien
Arts & Sciences Electronic Theses and Dissertations
The function of our nervous system relies on specific patterns of synaptic connections between diverse neuronal cell types. My thesis research addressed how cell-type-specific patterns of connectivity emerge in the developing mouse retina and how they enable mature retinal neurons to detect specific sensory stimuli.
Spike trains of the approximately 40 retinal ganglion cell (RGC) types in mammals encode specific features and events in the visual world, and are the sole source of visual information to the brain. Recent studies have begun to dissect the presynaptic circuits underlying diverse RGC light responses, but how cell-type-specific retinal circuits emerge during development …